Best GLP-1 Providers in South Carolina (2026)

Compare 140 GLP-1 telehealth providers available in South Carolina. Average compounded semaglutide cost: $195/mo.

140 providers$195/mo averageTelehealth legal

WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more

Featured Partners · South Carolina

Featured GLP-1 providers serving South Carolina

WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more

  1. Top pick

    Compounded from

    $199/mo

    Save $1,150/mo vs Wegovy
    Get started →
  2. Compounded from

    $147/mo

    Save $1,202/mo vs Wegovy
    Get started →
  3. 8.2

    Compounded from

    $129/mo

    Save $1,220/mo vs Wegovy
    Get started →
  4. Compounded from

    $249/mo

    Save $1,100/mo vs Wegovy
    Get started →
  5. Compounded from

    $99/mo

    Save $1,250/mo vs Wegovy
    Get started →
  6. Compounded from

    $99/mo

    Save $1,250/mo vs Wegovy
    Get started →

See by medication

Looking for a specific GLP-1? Browse South Carolina providers by drug.

About GLP-1s in South Carolina

South Carolina permits telehealth GLP-1 prescriptions. South Carolina Medicaid (Healthy Connections) covers GLP-1s only for type 2 diabetes.

  • South Carolina's adult obesity rate is 35.4%
  • Healthy Connections Medicaid restricts GLP-1 coverage to diabetes
  • Charleston is a growing Southeast telehealth market

All GLP-1 Providers Available in South Carolina

8.3/ 10
Verified partner

Found

Best for: mainstream telehealth GLP-1 access

★★★★4.2/5

Editorial score · methodology

$99/mo
CompoundedSemaglutideTirzepatideOrforglipron (foundayo)Semaglutide (wegovy)Tirzepatide (zepbound)Semaglutide (ozempic)Tirzepatide (mounjaro)
Get StartedRead full Found review →
8.1/ 10
Verified partner

RxSpan MD

Best for: shoppers wanting physician-led, pharmacy-transparent compounded GLP-1 with brand-name options

★★★★4.1/5

Editorial score · methodology

$179/mo
CompoundedSemaglutideTirzepatideLegitScript Verified
Get StartedRead full RxSpan MD review →
8.0/ 10
Verified partner

Strut Health

Best for: oral-lozenge compounded GLP-1 access

★★★★4/5

Editorial score · methodology

$99/mo
CompoundedSemaglutideTirzepatideLegitScript Verified
Get StartedRead full Strut Health review →
7.8/ 10
Verified partner

Yucca Health

Best for: mainstream telehealth GLP-1 access

★★★3.9/5

Editorial score · methodology

$146/mo
CompoundedSemaglutideTirzepatideNad+ (peptide, non-glp-1)Sermorelin (peptide, non-glp-1)
Get StartedRead full Yucca Health review →
7.8/ 10
Verified partner

Care Bare Rx

Best for: LGBTQ+-inclusive compounded GLP-1 telehealth

★★★3.9/5

Editorial score · methodology

$199/mo
CompoundedSemaglutideTirzepatide
Get StartedRead full Care Bare Rx review →
Browse all 140 providers in South Carolina A–Z

Also consider: 286 providers with undisclosed state coverage

These providers offer GLP-1 weight loss service (verified on their own websites) but do not publish a complete state-availability list publicly — their intake flow determines eligibility. We have not independently confirmed South Carolina coverage for the providers below. Start the signup intake to check whether they serve your state before proceeding.

8.1/ 10
Verified partner

GobyMeds

Best for: budget-conscious shoppers

★★★★4.1/5

Editorial score · methodology

$93/mo
CompoundedSemaglutideTirzepatideTirzepatide (zepbound)Semaglutide (wegovy)
Get StartedRead full GobyMeds review →
7.6/ 10
Verified partner

RNK Health

Best for: compounded GLP-1 alongside NAD+, peptide and longevity add-ons

★★★3.8/5

Editorial score · methodology

$197/mo
CompoundedSemaglutideTirzepatide
Get StartedRead full RNK Health review →
7.6/ 10
Verified partner

SkinnyRx

Best for: mainstream telehealth GLP-1 access

★★★3.8/5

Editorial score · methodology

$149.25/mo
CompoundedSemaglutideTirzepatideFDA Warning
Get StartedRead full SkinnyRx review →
6.9/ 10
Verified partner

YourEra

Best for: $99 first-month entry pricing on compounded GLP-1s

★★★3.5/5

Editorial score · methodology

$99/mo
CompoundedSemaglutideTirzepatideLegitScript Verified
Get StartedRead full YourEra review →
8.0/ 10
Verified partner

ShedRx

Best for: mainstream telehealth GLP-1 access

★★★★4/5

Editorial score · methodology

$149/mo
CompoundedSemaglutideTirzepatideOrforglipronMetformin + naltrexone + topiramate
Get StartedRead full ShedRx review →
7.7/ 10
Verified partner

TrimRx

Best for: best overall value

★★★3.9/5

Editorial score · methodology

$135/mo
CompoundedSemaglutideTirzepatideTirzepatide (mounjaro)Tirzepatide (zepbound)Semaglutide (wegovy)
Get StartedRead full TrimRx review →
Browse all 286 providers with undisclosed South Carolina coverage A–Z

Top Cities for GLP-1 Treatment in South Carolina

Telehealth providers ship to all South Carolina addresses, but demand is highest in these metro areas:

Prefer an in-person clinic? Browse the South Carolina GLP-1 clinic directory →

Insurance & Medicaid in South Carolina

South Carolina Medicaid GLP-1 Coverage
Diabetes only

Most insurance plans in South Carolina cover GLP-1s for type 2 diabetes (Ozempic, Mounjaro), but coverage for obesity-only indications (Wegovy, Zepbound) is much more limited and often requires prior authorization. If your insurance won't cover brand-name GLP-1s, compounded semaglutide through telehealth is typically the most affordable option at around $195/mo.

For the exact criteria, drug list, and appeal process, read our South Carolina Medicaid GLP-1 coverage & prior-authorization guide. For coverage backdoors, Zepbound is FDA-approved for obstructive sleep apnea, and Wegovy for kidney and cardiovascular indications, which some plans cover even when they exclude weight-loss-only use.

Obesity in South Carolina

According to CDC data, 35.4% of South Carolina adults have obesity (BMI of 30 or higher). This places South Carolina at #11 out of 50 states. Access to GLP-1 medications like semaglutide and tirzepatide has expanded significantly through telehealth, helping South Carolina residents get clinically supervised weight loss treatment from home.

To choose a medication, compare the clinical-trial results behind each drug, see our best semaglutide and tirzepatide provider rankings, or track the next-generation GLP-1 pipeline.

Frequently Asked Questions

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Get South Carolina Price Alerts

Be the first to know about new providers and price changes in South Carolina.