NewSelf Review

NewSelf: one of the cheapest compounded GLP-1 options, with a flat-price twist

NewSelf is built around a single, blunt promise: pay the same low price no matter how high your dose climbs. Its compounded semaglutide starts at $100 a month and its compounded tirzepatide isn't far behind — both among the lowest figures in our dataset, well under the $169 category median. If your main goal is to start a GLP-1 without draining your bank account, NewSelf earns a serious look. The catch is that this is a compounded-only, fairly young platform that also dabbles in 'AI health optimization' and longevity, so you're trusting a leaner operation than the big telehealth names.

How the flat-rate pricing actually works

Most GLP-1 providers raise your monthly bill every time your dose steps up — a slow squeeze that turns an affordable starter price into something much steeper by the time you reach a maintenance dose. NewSelf throws that model out. Its pricing cards say it plainly: 'One Price. Any Dose. Others charge more for higher doses — we don't.' So the semaglutide dose ladder (roughly the lowest microgram step up to the top maintenance dose) all bills at the same rate, and the same goes for tirzepatide across its full range.

There are two price tiers per drug: a 'best price' rate (the $100-a-month figure for semaglutide) and a slightly higher 'regular' rate. The lower number is the one NewSelf markets hardest, so confirm at checkout which tier you actually land in. Either way, there are no membership or program fees layered on top — NewSelf states the medication, the medical visit, and shipping are all bundled into the monthly price.

• Semaglutide+: from $100/mo at the best-price tier, with a modestly higher regular rate
• Tirzepatide+: a low-three-figure best-price rate, with a higher regular rate
• Every dose, one price — no escalation as you titrate up
• No membership fee — the visit and shipping are included, not add-ons

What's in the syringe: B12- and B6-enhanced compounds

NewSelf doesn't sell brand-name Wegovy, Ozempic, Zepbound, or Mounjaro — everything here is compounded. Its two products are 'Semaglutide+', combined with B12 and glycine, and 'Tirzepatide+', combined with B6 and glycine. The added vitamins are a common compounding flourish (B12 is often pitched for energy, glycine as a stabilizer); they're a nice-to-have, not a clinically proven booster, so don't choose NewSelf for the additives alone. Choose it for the price and the pharmacy practices behind it.

The trust signals that actually matter here

Cheap compounded GLP-1s are everywhere, and most of the risk lives in the pharmacy. This is where NewSelf is more transparent than many budget rivals. It is LegitScript certified, it works with 503A licensed pharmacies, and — importantly — it advertises third-party testing for potency, sterility, and endotoxicity. That last item matters: endotoxin and sterility testing are exactly the checks you want on an injectable, and a lot of low-cost sellers stay silent about them. NewSelf has an FDA warning letter on file, covered in the regulatory notice below.

Be clear-eyed about the ceiling, though. 503A pharmacies compound for individual prescriptions and aren't held to the same large-scale manufacturing standards as the FDA-registered 503B outsourcing facilities some competitors use. That's normal for this price tier, but it's a real difference. You can see how we weigh pharmacy accreditation, testing, and oversight in our scoring methodology.

Coverage, speed, and getting started

NewSelf covers 48 states plus Puerto Rico. The two gaps are Mississippi and Louisiana — if you live there, this one's off the table entirely. The intake starts with a free online visit ('Start My FREE Visit'), and NewSelf advertises a fast turnaround: from signup to treatment in as little as four days, with free shipping. For a budget provider, that's a genuinely quick path from click to first injection.

Who should pick NewSelf — and who shouldn't

NewSelf is a strong fit if you're paying cash, want the lowest realistic monthly cost, and expect to titrate to a higher maintenance dose where the flat-price model pays off most. It's also a good pick if you specifically want a compounder that publishes its sterility and potency testing rather than hand-waving about quality.

• Choose it if: you want rock-bottom monthly cost and plan to reach a higher dose where flat pricing saves the most
• Choose it if: you value visible third-party testing and LegitScript certification on a compounded product
• Skip it if: you live in Mississippi or Louisiana, or you want brand-name Wegovy, Zepbound, or insurance billing
• Skip it if: you'd rather use a 503B outsourcing facility or a longer-established telehealth brand

The bottom line

NewSelf is one of the best raw-value plays in compounded GLP-1 care: a sub-$169 price that doesn't balloon as your dose rises, no membership fees, fast free shipping, and unusually open pharmacy testing for the money. The honest caveats are that it's compounded-only, runs on 503A pharmacies rather than 503B, skips two states, and sits inside a broader, still-maturing wellness platform. If those trade-offs don't faze you, NewSelf delivers a lot of treatment for a little money. Confirm your exact price tier and your state's availability before you commit, and you'll know exactly what you're signing up for.

If you're weighing alternatives, bmiMD ($99/month) and Brightmeds ($100/month) are among the closest options we track to NewSelf.