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Joi + Blokes Review

Best for: GLP-1 alongside men's and women's hormone-health programs

Joi + Blokes is a hormone-first telehealth platform with parallel programs for women (Joi) and men (Blokes), now expanded to compounded GLP-1s for weight loss. The integrated hormone-plus-GLP-1 stack is its differentiator versus pure weight-loss telehealth — useful for patients already on testosterone or perimenopausal hormone protocols. Compounded semaglutide runs $99 the first month then $199/mo, and tirzepatide $149 then $299/mo, both billed quarterly.

By Eli Marsden · Founding Editor
Editorially reviewed (not clinically reviewed) · How we verify contentLast reviewed
8.0
★★★★4
CompoundedSemaglutideTirzepatideHealth CoachingHormone HealthMen + Women ProgramsQuarterly Billing
$99/mo

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Not disclosed

Lab work

Billed separately

Coaching

Included

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No insurance neededVetted by our editors

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The Bottom Line

Joi + Blokes is one of the most affordable GLP-1 options on the market.

Score: 8/10Best for: GLP-1 alongside men's and women's hormone-health programsFrom: $99/mo
Joi + Blokes logo
4.0 / 5
Our editorial rating
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from $99/mo · no insurance needed

Joi + Blokes at a glance

Type
GLP-1 telehealth provider
Medications
Semaglutide, Tirzepatide
Starting price
$99/mo
What's included
Medication · Consult · Coaching
FDA status
No FDA warning letter on record

How we scored Joi + Blokes

Each dimension is scored algorithmically from Joi + Blokes’s real pricing, drugs offered, verification status, and disclosed inclusions — using the same six-dimension framework we apply to every provider.

Value25%

9.1/10

At $99/mo, Joi + Blokes runs about 42% below the $170 median for GLP-1 providers.

Effectiveness25%

8.1/10

Joi + Blokes offers both semaglutide and tirzepatide — the two GLP-1 molecules with the strongest published weight-loss trial outcomes.

User Experience15%

7.4/10

Online intake and platform experience — consult included in the price; 7 platform features disclosed.

Trust & Safety15%

8.0/10

Core details confirmed by our editors; no FDA warning letters on file; dispenses through an accredited compounding pharmacy (last checked 2026-06-05).

Accessibility10%

6.1/10

Joi + Blokes's exact state footprint isn't published — confirm coverage in your state before signing up.

Support10%

7.8/10

Coaching/dietitian access included.

How we verified this Joi + Blokes review

Last checked 2026-06-05
  • Confirmed current pricing across 4 dose/plan tiers
  • Confirmed what the monthly price does and doesn't include
  • Checked the FDA warning-letter database for enforcement actions
  • Walked the public intake/checkout flow on the provider's site

Pricing, availability, and compliance facts come from the provider's own site and primary regulatory records — see the sources below. Editorial confidence in this data: medium.

GLP-1 medications Joi + Blokes offers

Tap any medication to read our plain-English guide — how it works, dosing, side effects, and what the trials found.

Peptides Joi + Blokes offers

Beyond GLP-1s, Joi + Blokes also offers these peptides — tap any for our evidence-based guide.

Pricing

Compounded semaglutide (first month)Compounded
$99/mo
semaglutide
Compounded semaglutide (months 2+, billed quarterly)Compounded
$199/mo
semaglutide
Compounded tirzepatide (first month)Compounded
$149/mo
tirzepatide
Compounded tirzepatide (months 2+, billed quarterly)Compounded
$299/mo
tirzepatide

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Plans and promotions change often — check Joi + Blokes's current pricing and active discounts before you decide.

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What we like

  • Separate programs for women (Joi) and men (Blokes) — most GLP-1 telehealth is gender-agnostic
  • Trustpilot 4.6/5 from 1,254+ reviews — among the strongest review signals in the category
  • Monthly price includes medication, dosing support, clinician consults, and health coaching
  • Integrated hormone + GLP-1 programs help patients on testosterone or perimenopausal protocols
  • First-month discount ($99 sema / $149 tirz) lowers the barrier to trying GLP-1s

Watch-outs

  • Billed quarterly — a 3-month commitment up front, not month-to-month
  • Different pricing in NY and NJ — verify your state's cost before committing
  • Per-state availability isn't listed; it's zip-code gated behind signup
  • Months 2+ cost more ($199 sema / $299 tirz) than the headline intro price
  • No FDA-approved Wegovy — compounded only on the GLP-1 side; Zepbound carries a separate visit fee
  • No LegitScript or PCAB accreditation badge visible

Joi + Blokes: the hormone-first platform that added GLP-1s

Most GLP-1 telehealth treats you as a generic weight-loss patient. Joi + Blokes does the opposite. It started as two hormone-health brands under one roof — Joi for women, Blokes for men — and bolted compounded GLP-1s onto programs already built around testosterone, perimenopause, and metabolic labs. That heritage is the whole reason to consider it. If you only want the cheapest shot in the mail, this isn't your pick. If you're a man on testosterone or a woman navigating perimenopausal hormone shifts and you want the GLP-1 layered into that same protocol, very few competitors are built to do it.

Two doors, one platform

The split into Joi and Blokes is more than branding. Nearly all GLP-1 telehealth is gender-agnostic — the same intake, the same coaching script, regardless of whether your weight is being pushed by low testosterone or by a hormonal transition. Here, men enter through Blokes and women through Joi, and the surrounding hormone programs are designed for those bodies specifically. For the right patient that's genuinely useful. For someone who just wants a clean, standalone weight-loss program, the hormone framing is extra surface area you don't need.

How the pricing actually works

The headline rate is $99 for your first month of compounded semaglutide, then a higher monthly rate after that. Compounded tirzepatide follows the same shape — a discounted first month, then a step up. The first-month discount is real and lowers the barrier to trying a GLP-1, but read past it: the ongoing months cost more than the teaser, so budget for the standing rate, not the intro.

The bigger thing to understand is the billing cadence. This is billed quarterly, not month-to-month. You're committing to a three-month block up front, not paying as you go. That's fine if you've decided you're in — GLP-1s take weeks to titrate and most people shouldn't be quitting in week three anyway — but it's a real commitment, and it's the single biggest difference between this and a cancel-anytime competitor.

One more pricing wrinkle: New York and New Jersey are priced differently than the rest of the country, and per-state availability isn't published openly — it's gated behind a zip-code check at signup. If you're in either of those states, confirm your actual number before you commit rather than trusting the national headline.

What's in the price — and what isn't

To its credit, the monthly fee is genuinely bundled. It covers your medication, dosing support, clinician consultations, and health coaching — including 1:1 coaching billed as unlimited health-coach visits. So the quarterly charge isn't a membership fee stacked on top of a separate drug cost; it's the all-in number.

  • Included: the compounded medication itself, dosing/titration support, clinician consults, and 1:1 health coaching
  • Not included: lab work. Functional labs are optional add-ons priced separately — useful if you want deeper metabolic insight, but not part of the monthly plan and not required to start
  • Watch for: brand-name Zepbound is referenced on the broader weight-loss side but carries a separate visit fee — it's not part of the headline GLP-1 program

Compounded only — know what that means

On the GLP-1 side, this is a compounded-only operation. You're getting compounded semaglutide or compounded tirzepatide, not FDA-approved Wegovy or Mounjaro through the core program. Compounded drugs are made by a pharmacy to order rather than mass-manufactured by the brand, which is how the price stays low — but it also means you're not getting the brand-name product the big trials studied. That's a legitimate trade-off thousands of patients accept, but you should make it knowingly. If brand-name only is a hard requirement for you, this isn't the right door.

Trust and oversight: strong reviews, thin badges

The customer-satisfaction signal here is one of the strongest in the category: a 4.6 out of 5 on Trustpilot across well over a thousand reviews — a sample size that's hard to fake and rare among GLP-1 startups. No FDA warning letters turn up for the company either. Those are real positives.

The caveats are about transparency, not safety complaints. We couldn't find a LegitScript or PCAB accreditation badge displayed, and the legal entity or parent company behind the two brands isn't disclosed on the main pages. None of that is evidence of wrongdoing — plenty of legitimate operators are quiet about corporate structure — but it does mean our verification confidence lands at medium rather than high. You're leaning on the review volume and a clean regulatory record more than on visible third-party credentials. See our scoring methodology for how we weigh that.

Who should choose it — and who should skip it

  • Choose it if: you're already in (or want to start) a hormone-health protocol — men's testosterone or women's perimenopausal care — and want a GLP-1 managed in the same place, and you're comfortable committing a quarter at a time
  • Skip it if: you want month-to-month flexibility, you require brand-name (non-compounded) medication, you live in NY or NJ and don't want to chase down state-specific pricing, or visible accreditation badges are a dealbreaker for you

Bottom line

Joi + Blokes is a niche pick that knows its lane. The integrated hormone-plus-GLP-1 stack is a real differentiator the gender-agnostic competition can't match, the bundle is honest about what it includes, and the review track record is excellent. The friction is the quarterly commitment, the compounded-only formulary, the NY/NJ pricing variance, and the missing accreditation badges. At $99 to start and a category-median rate of roughly $170 elsewhere, it's competitively priced — but the reason to come here isn't the price, it's the hormone-health context. Pick it for that, go in eyes-open on the three-month commitment, and confirm your state's number before you sign.

For a side-by-side, Telos Rx ($49/month) and bmiMD ($99/month) are the most comparable options to weigh against Joi + Blokes.

Ready to start with Joi + Blokes?

Starting at $99/month. See current pricing and start your free consultation.

Joi + Blokes might not be your best fit if…

We rank editorially, so here’s where a different provider we track may serve you better.

  • If you want brand-name Ozempic, Wegovy, Mounjaro or Zepbound, consider Gala.
  • If the lowest possible monthly price is your top priority, consider Telos Rx (from $49/mo).

Alternatives to Joi + Blokes

8.6/ 10
Verified partner

Enhance MD

Best for: lab-monitored compounded GLP-1 with mandatory video visit

★★★★4.3

Editorial score · methodology

$49/mo
CompoundedSemaglutideTirzepatide
Get StartedRead full Enhance MD review →
8.5/ 10
Verified partner

Embody

Best for: lowest first-month entry pricing on compounded GLP-1s

★★★★4.3

Editorial score · methodology

$99/mo
CompoundedSemaglutideTirzepatide
Get StartedRead full Embody review →
8.5/ 10
Verified partner

TrimRx

Best for: best overall value

★★★★4.3

Editorial score · methodology

$179/mo
CompoundedSemaglutide
Get StartedRead full TrimRx review →

Frequently Asked Questions

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Sources

The primary regulatory filings and peer-reviewed studies cited throughout this Joi + Blokes review:

Sources & methodology — as of July 2026
  1. 1.Weight Loss Rankings — GLP-1 Pricing Index 2026 (our independent dataset)WeightLossRankings.org.
  2. 2.FDA — Compounding and the 503A Pharmacy FrameworkU.S. Food & Drug Administration.
  3. 3.FDA — Drug Shortages Database (current shortage listings)U.S. Food & Drug Administration.
  4. 4.PCAB — Pharmacy Compounding Accreditation Board StandardsAccreditation Commission for Health Care (ACHC) / PCAB.
  5. 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)Kaiser Family Foundation.
  6. 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)New England Journal of Medicine.PMID: 33567185.
  7. 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDAU.S. Food & Drug Administration.
  8. 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDAU.S. Food & Drug Administration.
  9. 9.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)New England Journal of Medicine.PMID: 35658024.
  10. 10.FDA — Zepbound (tirzepatide) Approval History via Drugs@FDAU.S. Food & Drug Administration.
  11. 11.FDA — Mounjaro (tirzepatide) Prescribing Information via Drugs@FDAU.S. Food & Drug Administration.
  12. 12.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Garvey WT et al.)New England Journal of Medicine.PMID: 40334173.

Ready to start with Joi + Blokes?

Starting at $99/month. See current pricing and start your free consultation.