GLP-1 & Weight Loss Clinics in South Carolina

164 NPI-verified obesity-medicine, endocrinology, and bariatric practices across 75 South Carolina cities — sourced directly from the CMS National Provider registry. The directory also lists 313 facility-type clinics and 34 primary-care clinicians statewide whose CMS taxonomy also includes obesity medicine (see the Taxonomy Mix and per-city bands below).

South Carolina at a Glance

NPI-verified clinics
511
CMS national registry
Cities with a listing
75
Across South Carolina
Obesity-medicine + endo (core)
171
Primary taxonomy match
Bariatric surgery practices
277
Surgical taxonomy

Taxonomy Mix

Of the 511 South Carolina practices in this directory, 171 carry a core obesity-medicine or endocrinology taxonomy (6 Obesity Medicine, 165 Endocrinology, Diabetes & Metabolism), 2 are multi-specialty or primary-care clinic facilities, 277 carry a bariatric-surgery taxonomy, 3 carry a bariatric-medicine-adjacent combination taxonomy, 51 are family or internal medicine practices, and 7 are nurse-practitioner or physician-assistant enumerations.

Top Cities by Clinic Count

Cities with at least 3 clinics and 1 named, address-resolved practice have their own dedicated page. Smaller cities are listed below with their clinic count.

CityClinicsCore taxonomy
Charleston7033
Columbia4716
Greenville3116
Spartanburg2810
Mt Pleasant256
Myrtle Beach2313
West Columbia198
Florence1711
Rock Hill152
Anderson147
Greenwood111
Summerville116
Conway105
Sumter102
Bluffton91

All South Carolina Cities (75)

Browse all 75 South Carolina cities in this directory A–Z

In-Person vs Telehealth in South Carolina

The clinics in this directory are in-person obesity-medicine, endocrinology, and bariatric-surgery practices — a good fit if you want a local relationship, have complex needs, or need in-person documentation for insurance. Many South Carolina residents instead use a licensed telehealth provider that ships compounded semaglutide or tirzepatide directly to their address. Featured South Carolina telehealth partners:

Featured Partners · South Carolina

Featured GLP-1 providers serving South Carolina

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  1. Top pick
    8.1
    RxSpan MD

    Compounded from

    $179/mo

    Save $1,170/mo vs Wegovy
    Get started →
  2. 8.0
    Strut Health

    Compounded from

    $99/mo

    Save $1,250/mo vs Wegovy
    Get started →
  3. 7.8
    Yucca Health

    Compounded from

    $146/mo

    Save $1,203/mo vs Wegovy
    Get started →
  4. 7.6
    Sprout Health

    Compounded from

    $149/mo

    Save $1,200/mo vs Wegovy
    Get started →
  5. 7.5
    PeterMD

    Compounded from

    $215.67/mo

    Save $870.33/mo vs Zepbound
    Get started →
  6. 7.8
    Care Bare Rx

    Compounded from

    $199/mo

    Save $1,150/mo vs Wegovy
    Get started →
See all 155 GLP-1 providers serving South Carolina ↓

See our full list of GLP-1 telehealth providers serving South Carolina for pricing and reviews, or compare the best semaglutide and tirzepatide providers nationwide.

Frequently Asked Questions

Our directory lists 164 South Carolina practices whose true primary specialty on file is obesity medicine, endocrinology, or bariatric care, plus 313 clinics and medical centers and 34 primary-care clinicians whose CMS record also lists an obesity-medicine or endocrinology taxonomy — 511 in total across 75 South Carolina cities. Every count comes from the CMS National Provider registry (NPPES) taxonomy on file, not a survey of services.
The registry records each practice's specialty taxonomy, not the specific medications it prescribes or its current service menu. bariatric surgery is the most common taxonomy bucket among South Carolina listings in this directory (277 of 511 practices). Obesity-medicine and endocrinology practices commonly prescribe GLP-1 medications like semaglutide (Wegovy, Ozempic) and tirzepatide (Zepbound, Mounjaro), but we can't confirm any individual South Carolina clinic's offerings from the registry alone — call the practice directly to confirm availability, pricing, and new-patient status before booking.
It depends on your insurance and the medication. An in-person visit plus a brand-name prescription (Wegovy or Zepbound) can run $1,000-$1,350 per month without insurance, while licensed telehealth providers shipping compounded semaglutide or tirzepatide directly to South Carolina addresses average around $195/month cash-pay. See our full list of GLP-1 telehealth providers serving South Carolina in the "Prefer Telehealth?" section above.
Every listing is sourced from the CMS National Provider registry (NPPES), the federal database of enumerated healthcare providers. Across South Carolina we verified 164 primary-specialty practices, 313 facility-type listings, and 34 primary-care clinicians carrying a secondary obesity-medicine taxonomy this way — Charleston has the most listings of any South Carolina city in the directory, with 70. Listing reflects the taxonomy on file — it is not an endorsement, and not a confirmation of GLP-1 availability, cash-pay pricing, or new-patient status.