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RxSpan MD Review

8.1
★★★★☆4.1/5

Semaglutide & tirzepatide GLP-1 weight-loss telehealth · Independently scored 8.1/10

Best for: physician-led, pharmacy-transparent compounded GLP-1 with brand-name options

RxSpan MD stands out for its medical oversight and the pharmacy behind it.

Semaglutide

$249/mo

Tirzepatide

$329/mo

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Included

See plans →

No insurance neededVetted by our editors

RxSpan MD is a physician-led telehealth practice founded by Dr. John Diaz, a board-certified plastic surgeon, offering compounded GLP-1 weight loss (semaglutide and tirzepatide from $249/mo, as injections or oral capsules) plus brand-name Wegovy, Zepbound and Ozempic. It's unusually transparent: it names its 503A pharmacy partners (Belmar, Strive, Epiq Scripts, Casa Pharma) and medical group, ships free, and includes unlimited 24/7 support. Available in all 50 states.

By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
CompoundedSemaglutideTirzepatideBrand-name availablePhysician-ledLegitScript VerifiedShips to all 50 states

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RxSpan MD logo
4.1 / 5
Our editorial rating
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from $249/mo · no insurance needed

RxSpan MD at a glance

Type
GLP-1 telehealth provider
Medications
Semaglutide, Tirzepatide
Starting price
$249/mo
What's included
Medication · Consult · Shipping · Coaching
Availability
All 50 states
FDA status
No FDA warning letter on record

How we scored RxSpan MD

Each dimension is scored algorithmically from RxSpan MD’s published pricing, drugs offered, verification status, and disclosed inclusions, using the same six-dimension framework we apply to every provider.

Value25%

6.6/10

At $249/mo, RxSpan MD runs about 39% above the $179 median for GLP-1 providers (each program's lowest listed ongoing monthly price for compounded semaglutide).

Effectiveness25%

8.8/10

RxSpan MD offers both semaglutide and tirzepatide, the two GLP-1 molecules with the strongest published weight-loss trial outcomes. FDA-approved brand options are available alongside compounded versions.

User Experience15%

7.8/10

Online intake and platform experience (consult included in the price); 7 platform features disclosed.

Trust & Safety15%

9.7/10

Key details fully confirmed by our editors; no FDA warning letters on file; dispenses through an accredited compounding pharmacy; discloses which pharmacy makes its medication.

Accessibility10%

8.7/10

RxSpan MD treats patients in all 50 states.

Support10%

7.6/10

Coaching/dietitian access included.

6scored dimensions
642providers compared

Each checked against the provider’s own site.

Value 25%Effectiveness 25%User Experience 15%Trust & Safety 15%Accessibility 10%Support 10%

Providers that don’t post pricing up front score lower on Value and carry a cost-transparency note in their review. Read the full methodology →

How we verified this RxSpan MD review

Last checked August 2026
  • Confirmed current pricing across 7 dose/plan tiers
  • Confirmed availability in all 50 states
  • Confirmed what the monthly price does and doesn't include
  • Verified the compounding pharmacy partner and its accreditation
  • Checked the FDA warning-letter database for enforcement actions
  • Walked the public intake/checkout flow on the provider's site

Pricing, availability, and compliance facts come from the provider's own site and primary regulatory records. See the sources below. Editorial confidence in this data: high.

What we checked

Provider's own pricing page
$249–$1,349/mo across 7 dose/plan tiers (checked September 2026)
State pharmacy licensing & LegitScript status
LegitScript Verified
FDA warning-letter register
No letter on file for this provider
Compounding pharmacy partners
Belmar Pharmacy, Strive Pharmacy, Epiq Scripts, Casa Pharma Rx

What to expect when you sign up with RxSpan MD

We walked RxSpan MD’s public signup flow in July 2026 to document the process (the steps, pricing transparency, and what’s required) before you commit. (We don’t create accounts, enter medical information, or check out; this is the observable funnel, not a prescribing outcome.)

  1. 1Select your weight-loss goal from a quiz (Light 1-20 lbs, Medium 25-50 lbs, High 50+ lbs, or exploring).
  2. 2Take the online assessment/intake.
  3. 3A physician-guided review determines whether GLP-1 treatment is prescribed.
  4. 4If prescribed, medication is delivered via free, expedited delivery.
Price shown before you start
  • Every plan price is public before intake: the weight-loss category page opens a monthly / 3-month / 6-month / 12-month picker on each of the seven products.
  • A sitewide banner offers 'Save 10% on any order' with code STARTNOW, and the 12-month tier is now shown only with that code applied.
  • GLP-1 options advertised: compounded GLP-1, brand-name GLP-1, and microdosing GLP-1.
  • 'Free, expedited delivery' and '24/7 access to a dedicated team' claimed; no refund, cancellation, labs, or video-visit terms stated.
  • Public product/pricing detail is thin (category page returned 'No products found').

RxSpan MD customer support

GLP-1 medications RxSpan MD offers

Tap any medication to read our plain-English guide: how it works, dosing, side effects, and what the trials found.

Peptides RxSpan MD offers

Beyond GLP-1s, RxSpan MD also offers these peptides. Tap any for our evidence-based guide.

Pricing

Prices re-verified

Semaglutide InjectionCompounded
$249/mo
semaglutide

Month-to-month rate. Prepay equivalents on the weight-loss plan picker: $219/mo for 3 months, $199/mo for 6, and $175/mo for 12 with the sitewide STARTNOW code, billed as one upfront payment of $2,094.

Semaglutide CapsulesCompounded
$249/mo
semaglutide

Month-to-month rate. Prepay equivalents: $219/mo for 3 months, $199/mo for 6, and $162/mo for 12 with the STARTNOW code, billed as one upfront payment of $1,933.

Tirzepatide InjectionCompounded
$329/mo
tirzepatide

Month-to-month rate. Prepay equivalents: $309/mo for 3 months ($927 upfront), $289/mo for 6, and $243/mo for 12 with the STARTNOW code, billed as one upfront payment of $2,905.

Tirzepatide CapsulesCompounded
$349/mo
tirzepatide

Month-to-month rate. Prepay equivalents: $299/mo for 3 months ($897 upfront), $289/mo for 6, and $243/mo for 12 with the STARTNOW code, billed as one upfront payment of $2,905.

ZepboundBrand-name
$1,069/mo
tirzepatide

Monthly plan only ($1,069/mo).

OzempicBrand-name
$1,299/mo
semaglutide

Monthly plan only ($1,299/mo).

WegovyBrand-name
$1,349/mo
semaglutide

Monthly plan only ($1,349/mo).

Ready to get started?

Plans and promotions change often, so check RxSpan MD's current pricing and active discounts before you decide.

See RxSpan MD pricing →

RxSpan MD compounding-pharmacy partners

Each partner below is a 503A or 503B pharmacy that RxSpan MD routes prescriptions through.

Compare every compounding pharmacy we’ve reviewed →

What we like

  • Physician-led: founded by Dr. John Diaz, a board-certified plastic surgeon with 20+ years' experience
  • Compounded semaglutide and tirzepatide from $249/mo (injection or oral capsules), plus brand-name Wegovy, Zepbound and Ozempic
  • Names its 503A pharmacy partners (Belmar, Strive, Epiq Scripts, Casa Pharma) and medical group
  • LegitScript-certified (#50405601); free expedited shipping and unlimited 24/7 support included
  • Available in all 50 states via a 2-minute assessment

Watch-outs

  • Compounded pricing ($249 semaglutide / $329 tirzepatide) sits mid-to-high versus the cheapest telehealth options
  • Brand-name GLP-1 is priced steeply (Wegovy $1,349, Ozempic $1,299, Zepbound $1,069)
  • Multi-vertical practice (also hair, sexual health, longevity), not weight-loss-only
  • You pay at checkout before a clinician reviews you, and the site says a prescription is not guaranteed

RxSpan MD: a surgeon-led telehealth menu with every price out in the open

RxSpan MD publishes every price before you type a single letter of your name. Compounded semaglutide runs $249 a month on a month-to-month plan, injection or capsule, and compounded tirzepatide starts at $329. The number each card leads with, though, is the 12-month prepaid rate with a promo code already applied, billed as one upfront payment. The monthly figure sits above it in strikethrough gray.

It's a physician-led practice founded by Dr. John Diaz, a board-certified plastic surgeon, and it sells more than weight loss. The same storefront carries hair-loss, sexual-health, and longevity products. For GLP-1 buyers the draw is a rare combination: named compounding pharmacies, named prescribers with NPI numbers, and brand-name Wegovy, Ozempic, and Zepbound on the same page as the compounded versions.

How the pricing works

Pick a medication on the weight-loss page and a plan picker opens beneath it with four tiers for each compounded product: monthly, 3-month, 6-month, and 12-month. For semaglutide injection the monthly tier is $249, the 3-month tier takes about 12% off that, the 6-month tier about 20%, and the 12-month tier lands roughly 30% below it “with STARTNOW promo”. The 12-month tier is billed as one upfront payment covering the full year, and the card says it “Auto-renews”.

STARTNOW is a sitewide banner: “Save 10% on any order — use code STARTNOW.” Select the monthly plan and the total-if-prescribed line drops 10% below the $249 list price. Whether the discount carries into the second month isn't stated anywhere on the site. Assume it doesn't, and budget from the list price.

Tirzepatide follows the same shape: injection is $329 monthly, the 3-month and 6-month tiers trim roughly 6% and 12%, and the 12-month tier with the code lands about a quarter below the monthly rate. Capsules run $349 monthly and drop further on the 3-month plan than the injection does. The cheapest number on the whole menu is semaglutide capsules on a 12-month prepay, about 35% under the monthly rate.

The overview under the picker says the price “includes consult, medication, supplies, shipping, and support”. There's no membership fee and no separate consult charge, and plans are “Pre-paid monthly, quarterly, semi-annually, or annually”, with payment taken before anyone reviews your case: “Prescription is not guaranteed.” What happens to your money if you're declined isn't published, and the Terms of Service has no refund clause at all.

Against a category median of about $179, the monthly rate is mid-pack. The 12-month tiers are competitive, but only if you're sure you'll stay on the medication for a full year.

How we get the market median: $179 is the middle value of each program's lowest listed ongoing monthly price for compounded semaglutide (month to month, not a first-month promo, a prepaid plan or a price with a membership on top), across the 112 programs that publish one.

Medications, forms, and the dose question

All seven products sit on one page, four of them compounded: semaglutide injection, semaglutide capsules, tirzepatide injection, and tirzepatide capsules. Three are brand: Ozempic at $1,299, Zepbound at $1,069, and Wegovy at $1,349, each on a monthly plan only with no multi-month tier. RxSpan doesn't sell Mounjaro or the Wegovy pill, so the only oral options are the compounded capsules.

The compounded products list vitamin B12 as an added ingredient. The medication pages say dosing “is usually started low and increased gradually”, but RxSpan doesn't publish its own ladder in milligrams. If you want to know whether you'd move through the standard 0.25 mg to 2.4 mg semaglutide steps, or the 2.5 mg to 15 mg tirzepatide range, you'll have to ask the prescriber. Our semaglutide and tirzepatide pages cover what those ladders look like. Closer lab monitoring is the draw at GoodLife Health, whose primary care membership includes a lab panel every 90 days alongside brand-name GLP-1s, with the medication billed separately.

The price is flat across doses, so the 12-month rate you sign at is the rate you keep, on a starter dose and a maintenance dose alike. Dose-scaled competitors get expensive in month four; RxSpan doesn't.

The homepage also advertises a “Microdosing GLP-1” option. There's no microdosing product or price anywhere on the weight-loss menu, so treat that as a conversation with the provider, not a plan you can buy.

Dr. Diaz's own comparison page ranks the compounded capsules last for evidence, says there is no FDA-approved oral tirzepatide, and cites the trial doses behind each brand, which is unusually candid for a seller's page.

What signing up looks like

The intake starts at the plan picker, not after it. Choose a product, choose a tier, press Next, and the first screen asks for your first name, last name, email, and gender assigned at birth. That's where a window-shopper stops, because there's no anonymous quiz to test eligibility first.

The homepage calls it a 2-minute assessment in one place and says it “Takes about 5 minutes” in another. The How-It-Works section lists a “Virtual Consult” step, but the FAQ walks that back: “Not always. Many members are approved based on their assessment alone.”

After approval the prescription goes to one of four named 503A pharmacies: Belmar, Strive, Epiq Scripts, or Casa Pharma Rx. Which one fills yours isn't stated, and delivery is described only as “Free Expedited Delivery” with no day count published. Refills and check-ins run through the same provider, and the plan renews automatically at the term you chose. Support is “Unlimited 24/7”, with unlimited appointments and messaging included.

RxSpan says it serves “all 50 U.S. states”, with the caveat that specific services vary by state licensure.

Trust and safety

The trust picture is better than most compounded storefronts. The prescribers are named: Lion MD, led by Dr. Ana Lisa Carr and Dr. Kelly Tenbrink, both with NPI numbers on the site, and the pharmacies are named with phone numbers. The legal entity, RxSpan MD LLC, is in the Terms with a Beverly Hills address. A LegitScript seal sits in the footer, and there are no FDA warning letters against the company.

What's missing is the paperwork around your money. No refund policy, no statement about what a declined applicant gets back, and no explanation of how “Auto-renews” squares with “Cancel or change plans anytime”. The medication pages carry the standard compounded-drug disclosure: not FDA-approved, not reviewed for safety or effectiveness. RxSpan also doesn't say whether it takes insurance or HSA/FSA cards. Insured patients have another route in Knownwell, an obesity-medicine practice that accepts insurance for branded GLP-1s and runs clinics in four metro areas, though it doesn't post self-pay medication prices.

Who should choose it, and who should skip it

Choose RxSpan MD if you want the full price grid before giving anyone your email, if named pharmacies and named prescribers matter to you, and if you'd like to move between compounded and brand-name medication without switching providers. The 12-month capsule plan, about 35% under the monthly rate, is a low number for someone who already knows they'll stay the course.

Skip it if you're not ready to commit to a year, because the monthly rate is ordinary and the savings only arrive with prepay. Skip it if you need a refund policy in writing before you pay. And skip it if you want a clinic that only does weight loss, because the hair and sexual-health products share the same storefront.

RxSpan MD is a transparent-pricing compounded GLP-1 provider with a strong disclosure record and a weak refund record. Read the plan picker carefully, do the math on the upfront payment, and check the STARTNOW price on the checkout screen before you commit. See our scoring methodology for how those factors are weighed.

The Bottom Line

RxSpan MD stands out for its medical oversight and the pharmacy behind it.

Score: 8.1/10Best for: physician-led, pharmacy-transparent compounded GLP-1 with brand-name optionsFrom: $249/mo

Ready to start with RxSpan MD?

From $249/mo. See current pricing and start your free consultation.

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Editorial score · methodology

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BrandSemaglutideTirzepatideOrforglipron
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Best for: lowest-price compounded semaglutide and tirzepatide with one flat price at every dose

★★★★☆4.2/5

Editorial score · methodology

$79/mosemaglutide
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CompoundedSemaglutideTirzepatideNAD+SermorelinLegitScript Verified
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Head-to-head

Compare RxSpan MD vs…

RxSpan MD scores8.1/10

Side-by-side pricing, medications and scores. Pick a matchup.

All 46 RxSpan MD comparisons

Scores are our independent editorial ratings out of 10.

Frequently Asked Questions

RxSpan MD holds LegitScript certification (seal #50405601), a third-party standard confirming an online healthcare provider meets US legal and pharmacy compliance requirements. The practice was founded by Dr. John Diaz, a board-certified plastic surgeon with over 20 years of experience, and treatment plans are carried out under the Lion MD medical group. It also publicly names its 503A compounding pharmacy partners (Belmar Pharmacy, Strive Pharmacy, Epiq Scripts, and Casa Pharma Rx), an unusually transparent disclosure in the compounded GLP-1 space.
RxSpan MD is a physician-led telehealth practice founded by Dr. John Diaz that offers compounded and brand-name GLP-1 weight loss: semaglutide and tirzepatide as injections or oral capsules, plus brand-name Wegovy, Ozempic, and Zepbound for patients who prefer an FDA-approved finished product. All prescriptions are reviewed by physicians within the Lion MD medical group and dispensed by named 503A compounding pharmacies. The service is available in all 50 states and also covers longevity, hair, and sexual health under the same platform.
Compounded semaglutide (injection or oral capsules) is $249 per month, and compounded tirzepatide starts at $329 per month for injections and $349 per month for oral capsules. Brand-name options run significantly higher: Zepbound is $1,069 per month, Ozempic $1,299, and Wegovy $1,349. Free expedited shipping and unlimited 24/7 support are included with every plan. RxSpan MD does not publicly state whether it accepts insurance; reach their team at info@rxspanmd.com or 844-357-3601 for insurance or HSA/FSA eligibility questions.
RxSpan MD is one of the few compounded GLP-1 providers that publicly names its 503A pharmacy partners: Belmar Pharmacy, Strive Pharmacy, Epiq Scripts, and Casa Pharma Rx. All four are licensed 503A compounding pharmacies subject to state board of pharmacy oversight, and RxSpan MD's LegitScript certification requires continuous compliance monitoring. Which pharmacy fills your specific prescription depends on your medication type and state of residence; your care team can confirm the dispensing pharmacy once your plan is approved.
You complete a brief online assessment (estimated at about two minutes), and a licensed physician within the Lion MD medical group reviews your intake and creates a personalized treatment plan. Once prescribed, medication is dispensed by one of RxSpan MD's named 503A pharmacy partners and shipped free via expedited delivery. The plan includes unlimited appointments, messaging, and 24/7 support, so ongoing dose adjustments and check-ins happen through the same portal without additional fees.
Every RxSpan MD plan includes physician-prescribed medication, free expedited shipping, doctor-led coaching, and unlimited 24/7 support with no hidden fees. The compounded tier uses named 503A pharmacies; the brand-name tier (Wegovy, Ozempic, Zepbound) gives patients access to FDA-approved finished drug products at a higher monthly cost. As with all compounded GLP-1 services, compounded semaglutide and tirzepatide are not FDA-approved as finished drug products; only the active pharmaceutical ingredient holds FDA approval.
RxSpan MD doesn't use public promo or coupon codes: its $249/month includes the medication and the clinician visits, with no insurance or coupons needed. Third-party sites advertising "RxSpan MD discount codes" are typically fake; any current offer applies automatically through the link on this page.
We don't find any safety warnings on file (no FDA action). The concerns our review flags are mostly transparency-related: Compounded pricing ($249 semaglutide / $329 tirzepatide) sits mid-to-high versus the cheapest telehealth options; Brand-name GLP-1 is priced steeply (Wegovy $1,349, Ozempic $1,299, Zepbound $1,069); Multi-vertical practice (also hair, sexual health, longevity), not weight-loss-only; You pay at checkout before a clinician reviews you, and the site says a prescription is not guaranteed. None are safety issues, but they're worth weighing before you sign up.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Sources

The primary regulatory filings and peer-reviewed studies cited throughout this RxSpan MD review:

Sources & methodology (as of October 2026)
  1. 1.Weight Loss Rankings — GLP-1 Pricing Index 2026 (our independent dataset)— WeightLossRankings.org.
  2. 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
  3. 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
  4. 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
  5. 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
  6. 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
  7. 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
  8. 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
  9. 9.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
  10. 10.FDA — Zepbound (tirzepatide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
  11. 11.FDA — Mounjaro (tirzepatide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
  12. 12.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Garvey WT et al.)— New England Journal of Medicine.PMID: 40334173.

See RxSpan MD's current pricing

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