Jyra Health Review
Semaglutide & tirzepatide GLP-1 weight-loss telehealth · Independently scored 7.7/10
Best for: low-cost compounded semaglutide or tirzepatide with flat pricing at every dose
Jyra Health scores highest on state availability and ease of access.
Semaglutide
Tirzepatide
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not stated
Coaching
Not stated
No insurance needed · Vetted by our editors
Jyra Health is an online weight-loss and longevity telehealth clinic offering compounded semaglutide at $169/month and compounded tirzepatide at $229/month month-to-month, or $99 and $133 a month on a 3-month plan paid upfront. Prices stay flat at every dose and include the consultation, prescription and free express shipping, with no membership or insurance. It names its partner compounding pharmacies in Texas and Florida. Compounded medications are not FDA-approved, which the site discloses.
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Jyra Health at a glance
- Type
- GLP-1 telehealth provider
- Medications
- Semaglutide, Tirzepatide
- Starting price
- $169/mo
- Pricing model
- Flat: dose increases don't raise the monthly price
- What's included
- Medication · Consult · Shipping
- Availability
- All 50 states
- FDA status
- No FDA warning letter on record
How we scored Jyra Health
Each dimension is scored algorithmically from Jyra Health’s published pricing, drugs offered, verification status, and disclosed inclusions, using the same six-dimension framework we apply to every provider.
Value25%
8.0/10At $169/mo, Jyra Health runs about 6% below the $179 median for GLP-1 providers (each program's lowest listed ongoing monthly price for compounded semaglutide). Pricing is flat across doses, so there is no escalation markup as you titrate up.
Effectiveness25%
8.2/10Jyra Health offers both semaglutide and tirzepatide, the two GLP-1 molecules with the strongest published weight-loss trial outcomes.
User Experience15%
7.5/10Online intake and platform experience (consult included in the price); 8 platform features disclosed.
Trust & Safety15%
7.4/10Core details confirmed by our editors; no FDA warning letters on file.
Accessibility10%
8.4/10Jyra Health treats patients in all 50 states.
Support10%
6.0/10Jyra Health provides standard clinician follow-up; no extended coaching or community program is disclosed.
Each checked against the provider’s own site.
Providers that don’t post pricing up front score lower on Value and carry a cost-transparency note in their review. Read the full methodology →
How we verified this Jyra Health review
Last checked October 2026- Confirmed current pricing across 2 dose/plan tiers
- Confirmed availability in all 50 states
- Confirmed what the monthly price does and doesn't include
- Checked the FDA warning-letter database for enforcement actions
- Walked the provider's public sign-up flow, stopping before payment
Pricing, availability, and compliance facts come from the provider's own site and primary regulatory records. See the sources below. Editorial confidence in this data: medium.
What we checked
- Provider's own pricing page
- $169–$229/mo across 2 dose/plan tiers (checked October 2026)
- FDA warning-letter register
- No letter on file for this provider
What to expect when you sign up with Jyra Health
We walked Jyra Health’s public signup flow in October 2026 to document the process (the steps, pricing transparency, and what’s required) before you commit. (We don’t create accounts, enter medical information, or check out; this is the observable funnel, not a prescribing outcome.)
- 1Click Get Started and choose Weight Loss or Longevity.
- 2Read two intro screens on how GLP-1 medication works and what to expect (questionnaire about 3 minutes, physician review within 48 hours).
- 3Enter your email address to create an account or log in (we stopped here).
- 4Complete the health questionnaire; a licensed provider reviews it and, if approved, medication ships with free express delivery.
- Prices are on the homepage before you start: semaglutide $169 for 1 month or $99/mo on 3 months; tirzepatide $229 or $133/mo.
- The 3-month price is 'a one-time purchase paid upfront' ($297 or $399), which the treatment pages state clearly.
- Account creation with your email comes before any health questions.
- Turnaround is inconsistent: the homepage says about 24 hours for approval, while the intake says within 48 hours.
- Refund page: full refund if medication hasn't shipped, none after; plans auto-renew and you can cancel or pause anytime.
- Support by phone (346) 590-7290 and email, Monday to Friday 8am to 5pm Central.
Jyra Health customer support
- Phone
- (346) 590-7290
- Hours
- Mon-Fri 8am-5pm CST
GLP-1 medications Jyra Health offers
Tap any medication to read our plain-English guide: how it works, dosing, side effects, and what the trials found.
Pricing
Prices re-verified
$169/mo, flat at every dose; includes consult, prescription and free express shipping. Longer plan: 3-mo $99/mo ($297 upfront).
$229/mo, flat at every dose; includes consult, prescription and free express shipping. Longer plan: 3-mo $133/mo ($399 upfront).
Ready to get started?
Plans and promotions change often, so check Jyra Health's current pricing and active discounts before you decide.
What we like
- Month-to-month compounded semaglutide $169/mo and tirzepatide $229/mo, with no membership and no hidden fees
- 3-month plans cut the cost to $99/mo semaglutide or $133/mo tirzepatide
- Same price at every dose and at every renewal
- Names its partner compounding pharmacies, with addresses
- Free provider review; you are not charged for medication if you are not eligible
- Free express shipping, and providers available in all 50 states
- Phone and email support with published weekday hours
Watch-outs
- The advertised $99 and $133 prices require paying 3 months upfront ($297 or $399)
- Compounded medications are not FDA-approved (the site discloses this), not brand Wegovy, Zepbound, Ozempic, or Mounjaro
- Displays a self-hosted LegitScript badge rather than a verifiable seal
- No refund once medication has shipped
- Some partner pharmacies don't ship to every state, so your pharmacy depends on where you live
- You must create an account before answering any health questions
Is Jyra Health worth it?
Jyra Health built its program around one core idea: low-cost compounded semaglutide or tirzepatide with flat pricing at every dose. It runs $169/month at every dose, squarely in the middle of what this category charges, so what you get for it matters more here than the number itself. Its flat, all-dose pricing helps anyone worried about cost climbing as they titrate up.
Jyra Health charges the same price at every dose.
How much Jyra Health costs
Compounded semaglutide runs $169/month and compounded tirzepatide runs $229/month.
That's roughly in line with the ~$179/month median across the GLP-1 providers we track (each program's lowest listed ongoing monthly price for compounded semaglutide).
For a direct comparison, HealthRX runs semaglutide and tirzepatide from $165/month, so compare it with Jyra Health before you commit.
Medications: what Jyra Health prescribes
Jyra Health prescribes semaglutide (the active drug in Wegovy and Ozempic) and tirzepatide (the active drug in Zepbound and Mounjaro), the two most-studied weight-loss molecules on the market today. Rather than brand-name pens, you get a compounded formulation from a licensed pharmacy, which is why the monthly cost is lower. Just know compounded drugs aren't FDA-approved as finished products, the standard caveat in this market.
Who Jyra Health is best for, and who should skip it
A good fit if you…
- live anywhere in the US and want the certainty that your state is already covered.
Look elsewhere if you…
- specifically want an FDA-approved brand-name pen instead of a compounded formulation, which this provider doesn't fill.
- need to bill insurance, since like most of this market it's cash-pay with no claims filed on your behalf.
Trust, safety, and medical oversight
Jyra Health treats patients in all 50 states, and we found no FDA warning letter on file for it. As with any compounded program, the most important step you can take is confirming which licensed pharmacy fills your prescription and what's in the formulation, and we explain how in our scoring methodology.
Bottom line
Jyra Health is a reasonable telehealth GLP-1 option; weigh its pricing and coverage against the alternatives below before deciding.
The Bottom Line
Jyra Health scores highest on state availability and ease of access.
Ready to start with Jyra Health?
From $169/mo. See current pricing and start your free consultation.
Jyra Health might not be your best fit if…
We rank editorially, so here’s where a different provider we track may serve you better.
Head-to-head
Compare Jyra Health vs…
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Scores are our independent editorial ratings out of 10.
Frequently Asked Questions
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Sources
The primary regulatory filings and peer-reviewed studies cited throughout this Jyra Health review:
Sources & methodology (as of November 2026)
- 1.Weight Loss Rankings — GLP-1 Pricing Index 2026 (our independent dataset)— WeightLossRankings.org.
- 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
- 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
- 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
- 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
- 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
- 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 9.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
- 10.FDA — Zepbound (tirzepatide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 11.FDA — Mounjaro (tirzepatide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 12.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Garvey WT et al.)— New England Journal of Medicine.PMID: 40334173.
See Jyra Health's current pricing
Plans from $169/mo. Start your free consultation to check eligibility and today's price.