Yes Clinic Review

7.8
★★★★☆3.9/5

Semaglutide & tirzepatide GLP-1 weight-loss telehealth · Independently scored 7.8/10

Best for: flat per-dose pricing, and seeing every price without a quiz or an account

Price is where Yes Clinic scores best in our breakdown.

Semaglutide

$129/mo · 3-month plan rate

Tirzepatide

$149/mo · 3-month plan rate
Same price at every dose

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not stated

Coaching

Not stated

See plans →

No insurance neededVetted by our editors

Compare top-rated alternatives ↓

Yes Clinic sells compounded semaglutide and tirzepatide at one flat price that does not rise as your dose is titrated up: $129/mo for semaglutide and $149/mo for tirzepatide, with the consultation, shipping and membership all at $0. Every price is published on the product page without a quiz or an account. The trade-off is that the smallest plan is a three-month prepay charged upfront.

By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
CompoundedSemaglutideTirzepatideFlat Dose PricingNo MembershipFree Shipping

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Vetted alternatives to Yes Clinic

7.7/ 10
Verified partner

Ro

Best for: FDA-approved brand GLP-1s, including the Wegovy pill and Foundayo, with insurance help

★★★★☆3.9/5

Editorial score · methodology

$149/mosemaglutide
+ required membership
BrandSemaglutideTirzepatideOrforglipron
Get StartedRead full Ro review →
8.3/ 10
Verified partner

Collective

Best for: the lowest flat medication price if you can absorb an annual membership fee

★★★★☆4.2/5

Editorial score · methodology

$59/mosemaglutide
+ required membership
$69/motirzepatide
+ required membership
CompoundedSemaglutideTirzepatide
Get StartedRead full Collective review →
8.3/ 10
Verified partner

CoreAge Rx

Best for: lowest-price compounded semaglutide and tirzepatide with one flat price at every dose

★★★★☆4.2/5

Editorial score · methodology

$79/mosemaglutide
“starting at” price
$129/motirzepatide
“starting at” price
CompoundedSemaglutideTirzepatideNAD+SermorelinLegitScript Verified
Get StartedRead full CoreAge Rx review →
Yes Clinic
3.9 / 5
Our editorial rating
Visit Yes Clinic →

from $129/mo (3-month plan rate) · no insurance needed

Yes Clinic at a glance

Type
GLP-1 telehealth provider
Medications
Semaglutide, Tirzepatide
Starting price
$129/mo (3-month plan rate)
Pricing model
Flat: dose increases don't raise the monthly price
What's included
Medication · Consult · Shipping
FDA status
No FDA warning letter on record

How we scored Yes Clinic

Each dimension is scored algorithmically from Yes Clinic’s published pricing, drugs offered, verification status, and disclosed inclusions, using the same six-dimension framework we apply to every provider.

Value25%

9.1/10

At $129/mo (3-month plan rate), Yes Clinic runs about 28% below the $179 median for GLP-1 providers (each program's lowest listed ongoing monthly price for compounded semaglutide). Pricing is flat across doses, so there is no escalation markup as you titrate up.

Effectiveness25%

8.2/10

Yes Clinic offers both semaglutide and tirzepatide, the two GLP-1 molecules with the strongest published weight-loss trial outcomes.

User Experience15%

7.5/10

Online intake and platform experience (consult included in the price); 6 platform features disclosed.

Trust & Safety15%

7.4/10

Core details confirmed by our editors; no FDA warning letters on file.

Accessibility10%

6.2/10

Yes Clinic's exact state footprint isn't published. Confirm coverage in your state before signing up.

Support10%

6.0/10

Yes Clinic provides standard clinician follow-up; no extended coaching or community program is disclosed.

6scored dimensions
678providers compared

Each checked against the provider’s own site.

Value 25%Effectiveness 25%User Experience 15%Trust & Safety 15%Accessibility 10%Support 10%

Providers that don’t post pricing up front score lower on Value and carry a cost-transparency note in their review. Read the full methodology →

How we verified this Yes Clinic review

Last checked September 2026
  • Confirmed current pricing across 2 dose/plan tiers
  • Confirmed what the monthly price does and doesn't include
  • Checked the FDA warning-letter database for enforcement actions
  • Walked the provider's public sign-up flow, stopping before payment

Pricing, availability, and compliance facts come from the provider's own site and primary regulatory records. See the sources below. Editorial confidence in this data: medium.

What we checked

Provider's own pricing page
$129–$149/mo across 2 dose/plan tiers (checked September 2026)
FDA warning-letter register
No letter on file for this provider

What to expect when you sign up with Yes Clinic

We walked Yes Clinic’s public signup flow in September 2026 to document the process (the steps, pricing transparency, and what’s required) before you commit. (We don’t create accounts, enter medical information, or check out; this is the observable funnel, not a prescribing outcome.)

  1. 1Open the weight-loss category or a product page: every plan and price is visible with no quiz and no account
  2. 2Pick semaglutide or tirzepatide and choose a 3-month or 6-month plan
  3. 3Add to cart
  4. 4A separate 60-second quiz exists for people who want a recommendation first
Price shown before you start
  • The site states outright that no quiz and no account are needed to see any price
  • The dose slider demonstrates the flat-price claim: moving the dose leaves the price unchanged
  • There is no one-month option, so the real entry cost is $387 or $447 upfront rather than the headline monthly figure
  • Consultation, shipping and membership are each itemized at $0
  • The live Terms of Use still shows an unfilled {GOVERNING_LAW_STATE} placeholder, so governing law is undetermined

Yes Clinic customer support

Email
support@yesclinic.com

GLP-1 medications Yes Clinic offers

Tap any medication to read our plain-English guide: how it works, dosing, side effects, and what the trials found.

SemaglutideTirzepatide

Pricing

Prices re-verified

3-month plan, $387 charged upfrontCompounded
$129/mo
semaglutide

$387 for 3 months works out to $129/mo; 6 months is $699 ($116.50/mo) and is labeled "price locked". No single-month plan is offered, and the price is flat at every dose.

3-month plan, $447 charged upfrontCompounded
$149/mo
tirzepatide

$447 for 3 months and $894 for 6 months both work out to $149/mo, labeled "price locked". No single-month plan is offered, and the price is flat at every dose.

Ready to get started?

Plans and promotions change often, so check Yes Clinic's current pricing and active discounts before you decide.

See Yes Clinic pricing →

What we like

  • Flat price at every dose ($129/mo semaglutide, $149/mo tirzepatide) that does not climb as you titrate
  • At $129/mo semaglutide sits only $20 below tirzepatide, so stepping up costs little
  • No email wall to see cost: "Every price is on this page. No quiz and no account needed to see it"
  • Consultation ($30), shipping and membership are all listed at $0: "the price on the tile is the whole price"
  • Full refund if you cancel before the pharmacy dispenses; cancel yourself from your account
  • Bilingual site with a working EN/ES toggle

Watch-outs

  • Smallest plan is a 3-month prepay, so $387 or $447 is charged upfront rather than billed monthly
  • Their live Terms of Use still contains an unfilled template placeholder: governed by the laws of the State of {GOVERNING_LAW_STATE}
  • No pharmacy partner is named despite a "LegitScript Certified" banner in the footer
  • No state list published: "Services are not available in all states"
  • Product pages' underlying code has listed different prices than the ones shown, so go by the figure on screen
  • Support is email-only; no phone number published

Is Yes Clinic worth it?

What Yes Clinic is selling, in one line, is flat per-dose pricing, and seeing every price without a quiz or an account. It runs $129/month (3-month plan rate) at every dose; there's no clean category median to weigh that against, but it's a published number rather than one you find out only after signing up. Its flat, all-dose pricing helps anyone worried about cost climbing as they titrate up.

It charges the same price at every dose.

How much Yes Clinic costs

Compounded semaglutide runs $129/month (3-month plan rate) and compounded tirzepatide runs $149/month (3-month plan rate).

Because Yes Clinic's headline figure is a 3-month plan rate, we don't set it against the roughly $179 market median for this category. That median is each program's lowest listed ongoing monthly price for compounded semaglutide, so compare Yes Clinic with the month-to-month prices of the alternatives below instead.

Brightmeds (about $129/month) is one of the closest alternatives to weigh Yes Clinic against.

Medications: what Yes Clinic prescribes

Yes Clinic prescribes semaglutide (the active drug in Wegovy and Ozempic) and tirzepatide (the active drug in Zepbound and Mounjaro), the two molecules with the strongest published weight-loss trial outcomes. Rather than brand-name pens, you get a compounded formulation from a licensed pharmacy, which is why the monthly cost is lower. Just know compounded drugs aren't FDA-approved as finished products, the standard caveat in this market.

Who Yes Clinic is best for, and who should skip it

A good fit if you…

  • want a straightforward telehealth GLP-1 program and are comfortable comparing it against the alternatives below.

Look elsewhere if you…

  • specifically want an FDA-approved brand-name pen instead of a compounded formulation, which this provider doesn't fill.
  • need to bill insurance, since like most of this market it's cash-pay with no claims filed on your behalf.

Trust, safety, and medical oversight

We found no FDA warning letter on file for it, though a clean record isn't the same as an endorsement, so read the rest of this review for the full picture. As with any compounded program, the most important step you can take is confirming which licensed pharmacy fills your prescription and what's in the formulation, and we explain how in our scoring methodology.

Bottom line

Yes Clinic is a reasonable telehealth GLP-1 option; weigh its pricing and coverage against the alternatives below before deciding.

The Bottom Line

Price is where Yes Clinic scores best in our breakdown.

Score: 7.8/10Best for: flat per-dose pricing, and seeing every price without a quiz or an accountFrom: $129/mo (3-month plan rate)

Ready to start with Yes Clinic?

From $129/mo (3-month plan rate). See current pricing and start your free consultation.

Visit Yes Clinic →

Yes Clinic might not be your best fit if…

We rank editorially, so here’s where a different provider we track may serve you better.

  • If you want brand-name Ozempic, Wegovy, Mounjaro or Zepbound, consider altRX.
  • If the lowest possible monthly price is your top priority, consider YourEra (from $89/mo).
  • If you want built-in coaching and behavior-change support, consider Ro.
See all alternatives to Yes Clinic →

Head-to-head

Compare Yes Clinic vs…

Yes Clinic scores7.8/10

Side-by-side pricing, medications and scores. Pick a matchup.

Scores are our independent editorial ratings out of 10.

Frequently Asked Questions

Yes Clinic sells compounded semaglutide and tirzepatide at one flat price that does not rise as your dose is titrated up: $129/mo for semaglutide and $149/mo for tirzepatide, with the consultation, shipping and membership all at $0. Every price is published on the product page without a quiz or an account. The trade-off is that the smallest plan is a three-month prepay charged upfront. We scored it 7.8/10 across our six-dimension editorial framework.
Yes. Yes Clinic is a legitimate telehealth provider. Our editors independently verified its pricing and offering and scored it 7.8/10 across our six-dimension framework. As with any medication, consult a licensed clinician before starting.
Yes Clinic starts at $129/month (3-month plan rate). The price is flat across doses, so it doesn't increase as you titrate up. See the pricing table above for every tier.
Yes Clinic doesn't use public promo or coupon codes. Third-party sites advertising "Yes Clinic discount codes" are typically fake; any current offer applies automatically through the link on this page.
Yes Clinic hasn't published its exact state footprint. Confirm coverage in your state before signing up.
Yes Clinic offers semaglutide (the active drug in Wegovy/Ozempic) and tirzepatide (the active drug in Zepbound/Mounjaro). These are dispensed as compounded formulations.
Yes Clinic dispenses compounded GLP-1s made by a licensed compounding pharmacy, with the same active ingredient as the brand drugs at a lower cash price. Compounded drugs are not FDA-approved as finished products; we cover what that means in the review.
Yes Clinic is a cash-pay program. No insurance is required, which is why the monthly price is transparent up front.
Yes Clinic's price includes medication, the clinician consult and shipping. See the "what's included" strip near the top of this review.
You complete an online intake, a licensed clinician looks at whether a GLP-1 fits your situation, and, if you're approved, your medication ships to your door. You can begin the consultation directly on Yes Clinic's site.
We don't find any safety warnings on file (no FDA action). The concerns our review flags are mostly transparency-related: Smallest plan is a 3-month prepay, so $387 or $447 is charged upfront rather than billed monthly; Their live Terms of Use still contains an unfilled template placeholder: governed by the laws of the State of {GOVERNING_LAW_STATE}; No pharmacy partner is named despite a "LegitScript Certified" banner in the footer; No state list published: "Services are not available in all states". None are safety issues, but they're worth weighing before you sign up.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Sources

The primary regulatory filings and peer-reviewed studies cited throughout this Yes Clinic review:

Sources & methodology (as of November 2026)
  1. 1.Weight Loss Rankings — GLP-1 Pricing Index 2026 (our independent dataset)— WeightLossRankings.org.
  2. 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
  3. 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
  4. 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
  5. 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
  6. 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
  7. 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
  8. 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
  9. 9.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
  10. 10.FDA — Zepbound (tirzepatide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
  11. 11.FDA — Mounjaro (tirzepatide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
  12. 12.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Garvey WT et al.)— New England Journal of Medicine.PMID: 40334173.

See Yes Clinic's current pricing

Plans from $129/mo (3-month plan rate). Start your free consultation to check eligibility and today's price.

Visit Yes Clinic →