TMates Review

Best for: nationwide compounded GLP-1 availability including Puerto Rico

TMates is a Miami-based telehealth platform offering compounded semaglutide ($199/mo) and tirzepatide ($297/mo) across all 50 states plus Puerto Rico, operating on a messaging-first model with independent licensed prescribers and third-party compounding pharmacies.

Medium confidence · Last verified 2026-04-09 via manual · How we verify provider data

6.3
★★★☆☆3.2
CompoundedSemaglutideTirzepatideAll 50 States + PR

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The Bottom Line

TMates is a solid telehealth option with balanced features and pricing.

Score: 6.3/10Best for: nationwide compounded GLP-1 availability including Puerto RicoFrom: $199/mo

Score Breakdown

Value
7
Effectiveness
6
User Experience
6
Trust & Safety
5
Accessibility
8
Support
6

Pricing

DoseFormPrice/mo
Startingcompounded$199
Startingcompounded$297

Pros

  • All-inclusive monthly pricing covers medication, consultations, nutrition coaching, and 24/7 support with no separate membership fee
  • Available in all 50 US states plus Puerto Rico and other US territories
  • Both compounded semaglutide and tirzepatide offered
  • Fast stated turnaround (intake to medication delivery in 2–3 days)

Cons

  • No disclosed third-party accreditations (no verified LegitScript, PCAB, ACHC, or NABP) — weaker pharmacy-oversight signal than competitors
  • BBB rating B+ (not accredited) with 8 complaints filed, most involving billing and cancellation friction
  • Trustpilot reviews show partial-refund and contact-difficulty reports, and some customer posts allege reviews have been removed
  • Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
  • Pharmacy partners not publicly named — TMates explicitly disclaims both medical practice and pharmacy dispensing responsibility, routing both to independent third parties
  • Also sells Schedule III testosterone products and other wellness SKUs alongside GLP-1s — worth knowing about for readers who want a GLP-1-focused provider

Ready to start with TMates?

Starting at $199/month. See current pricing and start your free consultation.

Sources & methodology

Our TMates review applies the same 6-dimension scoring framework we use for every provider. Pricing, FDA approval status, compounding rules, and clinical-trial efficacy claims are sourced from the primary regulatory and peer-reviewed literature below.

Sources & methodology — as of April 2026
  1. 1.Weight Loss Rankings — GLP-1 Pricing Index 2026 (our independent dataset)WeightLossRankings.org.
  2. 2.FDA — Compounding and the 503A Pharmacy FrameworkU.S. Food & Drug Administration.
  3. 3.FDA — Drug Shortages Database (current shortage listings)U.S. Food & Drug Administration.
  4. 4.PCAB — Pharmacy Compounding Accreditation Board StandardsAccreditation Commission for Health Care (ACHC) / PCAB.
  5. 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)Kaiser Family Foundation.
  6. 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)New England Journal of Medicine.PMID: 33567185.
  7. 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDAU.S. Food & Drug Administration.
  8. 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDAU.S. Food & Drug Administration.
  9. 9.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)New England Journal of Medicine.PMID: 35658024.
  10. 10.FDA — Zepbound (tirzepatide) Approval History via Drugs@FDAU.S. Food & Drug Administration.
  11. 11.FDA — Mounjaro (tirzepatide) Prescribing Information via Drugs@FDAU.S. Food & Drug Administration.
  12. 12.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Garvey WT et al.)New England Journal of Medicine.PMID: 40334173.

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Frequently Asked Questions

Ready to start with TMates?

Starting at $199/month. See current pricing and start your free consultation.