TotalRx Review
7.4
★★★★☆3.7/5
Semaglutide & tirzepatide GLP-1 weight-loss telehealth · Independently scored 7.4/10
Best for: low-cost compounded semaglutide or tirzepatide on a prepaid 12-month plan
Price is where TotalRx scores best in our breakdown.
Semaglutide
$129/mo
Tirzepatide
$174/mo
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
See plans →See plans at TotalRx →
Compare top-rated alternatives ↓No insurance needed · Vetted by our editors
TotalRx is a new GLP-1 telehealth brand run by Coravita Health that offers compounded semaglutide and tirzepatide, prescribed through the OpenLoop clinician network and filled by four named pharmacies. Plans run from $129/mo for semaglutide and $174/mo for tirzepatide on a 12-month prepay, or $199 and $249 month to month, with a price-for-life pitch while the plan stays active.
By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
CompoundedSemaglutideTirzepatideLegitScript VerifiedFree ShippingHSA/FSA Eligible
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CompoundedSemaglutideTirzepatideFDA Warning
Get StartedRead full MEDVi review →6.9/ 10
Verified partnerDudeMeds
Best for: men seeking no-fee compounded or brand-name GLP-1 injections
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$175/mosemaglutide
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CompoundedSemaglutideTirzepatideNAD+
Get StartedRead full DudeMeds review →8.1/ 10
Verified partnerOak
Best for: compounded semaglutide and tirzepatide at a low starting price, with a full price list before you sign up
★★★★☆4.1/5
Editorial score · methodology
$133/mosemaglutide
$199/motirzepatide
CompoundedSemaglutideTirzepatideGlutathioneNAD+
Get StartedRead full Oak review →TotalRx at a glance
- Type
- GLP-1 telehealth provider
- Medications
- Semaglutide, Tirzepatide
- Starting price
- $129/mo
- What's included
- Medication · Consult · Shipping
- FDA status
- No FDA warning letter on record
How we scored TotalRx
Each dimension is scored algorithmically from TotalRx’s real pricing, drugs offered, verification status, and disclosed inclusions — using the same six-dimension framework we apply to every provider.
Value25%
8.3/10At $129/mo, TotalRx runs about 28% below the $179 median for GLP-1 providers.
Effectiveness25%
7.8/10TotalRx offers both semaglutide and tirzepatide — the two GLP-1 molecules with the strongest published weight-loss trial outcomes.
User Experience15%
7.1/10Online intake and platform experience — consult included in the price; 6 platform features disclosed.
Trust & Safety15%
7.5/10Core details confirmed by our editors; no FDA warning letters on file; discloses which pharmacy makes its medication.
Accessibility10%
6.2/10TotalRx's exact state footprint isn't published — confirm coverage in your state before signing up. FSA/HSA cards are accepted.
Support10%
5.6/10TotalRx provides standard clinician follow-up; no extended coaching or community program is disclosed.
6scored dimensions
642providers compared
Each checked against the provider’s own site.
Value 25%Effectiveness 25%User Experience 15%Trust & Safety 15%Accessibility 10%Support 10%
Providers that don’t post pricing up front score lower on Value and carry a cost-transparency note in their review. Read the full methodology →
How we verified this TotalRx review
Last checked October 2026- Confirmed current pricing across 4 dose/plan tiers
- Confirmed what the monthly price does and doesn't include
- Verified the compounding pharmacy partner and its accreditation
- Checked the FDA warning-letter database for enforcement actions
- Walked the public intake/checkout flow on the provider's site
Pricing, availability, and compliance facts come from the provider's own site and primary regulatory records — see the sources below. Editorial confidence in this data: medium.
What we checked
- Provider's own pricing page
- $129–$249/mo across 4 dose/plan tiers — checked October 2026
- State pharmacy licensing & LegitScript status
- LegitScript Verified
- FDA warning-letter register
- No letter on file for this provider
- Compounding pharmacy partners
- RedRock Pharmacy, Health Warehouse, Precision Medicine, Triad Rx
What to expect when you sign up with TotalRx
We walked TotalRx’s public signup flow in October 2026 to document the process — the steps, pricing transparency, and what’s required — before you commit. (We don’t create accounts, enter medical information, or check out; this is the observable funnel, not a prescribing outcome.)
- 1Homepage shows 'From $129/mo' semaglutide and 'From $174/mo' tirzepatide cards and a Start my assessment button
- 2The assessment opens on 'What do you want to treat first?'; weight loss is the only live option, the others say coming soon
- 3A roughly 40-screen health intake follows: height, weight, goal weight, sex, date of birth, conditions, medications, vitals
- 4A results screen labeled 'Eligibility review · Cleared' shows a GLP-1 match score, then asks for name, state, email and phone
- 5After contact details: treatment choice, plan picker (monthly, 3, 6 or 12 months), Stripe checkout, then optional add-ons
- 6A clinician licensed in your state reviews the intake, 'usually within 24 hours', with a video or phone visit 'where required'
Price shown before you start
- Walked the public funnel only: we stopped at the first health question (height). No account was created, no data was entered and nothing was paid
- Headline prices are on the homepage, but the full plan picker only appears after you hand over name, email and phone
- The plan list on the site shows 'Monthly' is a 4-week supply and '12-Month' is a 48-week supply billed upfront
- The 94/100 'match score' is a fixed value in the form, not something calculated from your answers
- The intake's BMI cut-off is 22, well below the BMI 27–30 range in the FDA labels for GLP-1 weight-loss drugs; the clinician still decides
- Payment comes first: 'Charged at checkout · refunded in full if not prescribed'
- Post-checkout upsells in the plan data: an 'Expedited live visit' at $49.95 and a 'TotalRx Comfort Kit' at $29
- We did not take the medication and cannot report outcomes
TotalRx customer support
- support@totalrx.com
- Hours
- Mon–Fri 8am–8pm ET (email; typical response within 1 business day)
GLP-1 medications TotalRx offers
Tap any medication to read our plain-English guide — how it works, dosing, side effects, and what the trials found.
Pricing
Prices re-verified
12-month plan (48-week supply, $1,548 paid upfront)Compounded
$129/mo
semaglutide
$129/mo is the average of one $1,548 upfront charge for a 48-week supply. 6-month plan $139/mo ($834 upfront, 24 weeks); 3-month plan $149/mo ($447 upfront, 12 weeks).
Monthly plan (4-week supply, renews every 4 weeks)Compounded
$199/mo
semaglutide
No-commitment option. Each 'month' is a 4-week supply, so a year of renewals is 13 charges.
12-month plan (48-week supply, $2,088 paid upfront)Compounded
$174/mo
tirzepatide
$174/mo is the average of one $2,088 upfront charge for a 48-week supply. 6-month plan $189/mo ($1,134 upfront, 24 weeks); 3-month plan $199/mo ($597 upfront, 12 weeks).
Monthly plan (4-week supply, renews every 4 weeks)Compounded
$249/mo
tirzepatide
No-commitment option. Each 'month' is a 4-week supply, so a year of renewals is 13 charges.
Ready to get started?
Plans and promotions change often — check TotalRx's current pricing and active discounts before you decide.
TotalRx compounding-pharmacy partners
Each partner below is a 503A or 503B pharmacy that TotalRx routes prescriptions through.
What we like
- Names all four dispensing pharmacies in its terms, with addresses and phone numbers
- Names its clinical network: OpenLoop Healthcare Partners PC
- Publishes every plan price, from $129/mo semaglutide and $174/mo tirzepatide on a 12-month plan
- Month-to-month option at $199 semaglutide or $249 tirzepatide, with no prepay required
- Full refund if a clinician finds you ineligible after you are charged at checkout
- Free cold shipping and a stated 1–2 business day ship time after approval
Watch-outs
- The $129 and $174 headline prices require one upfront charge of $1,548 or $2,088 for a 48-week supply
- A plan 'month' is a 4-week supply, so month-to-month means 13 charges a year
- Markets 'price for life', but its terms say it may change subscription prices
- You pay at checkout before a clinician reviews your intake
- The intake shows every applicant the same 94/100 'match score' before a clinician has looked at it
- Support is email only during weekday hours; no phone line is published
- New brand with no Trustpilot or BBB profile yet
- Compounded GLP-1s are not shipped to Louisiana
Is TotalRx worth it?
What TotalRx is selling, in one line, is low-cost compounded semaglutide or tirzepatide on a prepaid 12-month plan. It runs $129/month — toward the affordable end of the category, so cost isn't the reason to look elsewhere. It's a fairly plain, no-frills entry in the GLP-1 providers category, without a lot of extra add-ons layered on top of the medication itself.
TotalRx is LegitScript-certified and takes HSA/FSA payment.
How much TotalRx actually costs
Compounded semaglutide runs $129–$199/month depending on plan and compounded tirzepatide runs $174–$249/month depending on plan.
That puts TotalRx below the roughly $179 median ongoing price across the GLP-1 providers we track — a real cost advantage.
Live Vital (about $130/month) is one of the closest alternatives to weigh TotalRx against.
Medications: what TotalRx prescribes
TotalRx prescribes semaglutide (the active drug in Wegovy and Ozempic) and tirzepatide (the active drug in Zepbound and Mounjaro) — the pair backed by the largest published weight-loss trials. The medication is compounded at a licensed pharmacy rather than sold as a brand pen, which is what keeps the price down. The trade-off is the one every compounded provider shares: compounded drugs aren't FDA-approved as finished products.
Who TotalRx is best for — and who should skip it
A good fit if you…
- are focused on the lowest ongoing monthly cost — $129/month is below the roughly $179 median we track across the category.
Look elsewhere if you…
- specifically want an FDA-approved brand-name pen instead of a compounded formulation — that's not what this provider fills.
- need to bill insurance, since like most of this market it's cash-pay with no claims filed on your behalf.
Trust, safety, and medical oversight
TotalRx names the pharmacy that fills its prescriptions, and we found no FDA warning letter on file for it. As with any compounded program, the most important step you can take is confirming which licensed pharmacy fills your prescription and what's in the formulation — we explain how in our scoring methodology.
Bottom line
TotalRx earns its place on the shortlist mainly on price: at $129/month it's one of the more affordable ways to stay on a GLP-1, without obvious corners cut on access or oversight.
The Bottom Line
Price is where TotalRx scores best in our breakdown.
Score: 7.4/10Best for: low-cost compounded semaglutide or tirzepatide on a prepaid 12-month planFrom: $129/mo
Ready to start with TotalRx?
Starting at $129/month. See current pricing and start your free consultation.
TotalRx might not be your best fit if…
We rank editorially, so here’s where a different provider we track may serve you better.
- If you want brand-name Ozempic, Wegovy, Mounjaro or Zepbound, consider altRX.
- If the lowest possible monthly price is your top priority, consider Collective (from $59/mo).
- If you want built-in coaching and behavior-change support, consider MEDVi.
Frequently Asked Questions
TotalRx is a new GLP-1 telehealth brand run by Coravita Health that offers compounded semaglutide and tirzepatide, prescribed through the OpenLoop clinician network and filled by four named pharmacies. Plans run from $129/mo for semaglutide and $174/mo for tirzepatide on a 12-month prepay, or $199 and $249 month to month, with a price-for-life pitch while the plan stays active. We scored it 7.4/10 across our six-dimension editorial framework.
Yes — TotalRx is a legitimate telehealth provider. Our editors independently verified its pricing and offering and scored it 7.4/10 across our six-dimension framework. As with any medication, consult a licensed clinician before starting.
TotalRx starts at $129/month. See the pricing table above for every tier.
TotalRx doesn't use public promo or coupon codes — its $129/month is an all-inclusive cash price with no insurance or coupons needed. Third-party sites advertising "TotalRx discount codes" are typically fake; any current offer applies automatically through the link on this page.
TotalRx hasn't published its exact state footprint. Confirm coverage in your state before signing up.
TotalRx offers semaglutide (the active drug in Wegovy/Ozempic) and tirzepatide (the active drug in Zepbound/Mounjaro). These are dispensed as compounded formulations.
TotalRx dispenses compounded GLP-1s made by a licensed compounding pharmacy — the same active ingredient as the brand drugs at a lower cash price. Compounded drugs are not FDA-approved as finished products; we cover what that means in the review.
TotalRx is a cash-pay program (no insurance required) and accepts FSA/HSA cards.
TotalRx's price includes medication, the clinician consult and shipping. See the "what's included" strip near the top of this review.
You complete an online intake, a licensed clinician reviews whether a GLP-1 is appropriate for you, and — if approved — your medication ships to your door. You can begin the consultation directly on TotalRx's site.
We don't find any safety warnings on file (no FDA action). The concerns our review flags are mostly transparency-related: The $129 and $174 headline prices require one upfront charge of $1,548 or $2,088 for a 48-week supply; A plan 'month' is a 4-week supply, so month-to-month means 13 charges a year; Markets 'price for life', but its terms say it may change subscription prices; You pay at checkout before a clinician reviews your intake. None are safety issues, but they're worth weighing before you sign up.
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Sources
The primary regulatory filings and peer-reviewed studies cited throughout this TotalRx review:
Sources & methodology — as of October 2026
- 1.Weight Loss Rankings — GLP-1 Pricing Index 2026 (our independent dataset)— WeightLossRankings.org.
- 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
- 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
- 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
- 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
- 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
- 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 9.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
- 10.FDA — Zepbound (tirzepatide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 11.FDA — Mounjaro (tirzepatide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 12.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Garvey WT et al.)— New England Journal of Medicine.PMID: 40334173.
See TotalRx's current pricing
Plans start at $129/month. Start your free consultation to check eligibility and today's price.
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