Arc-1 Review
Best for: patients seeking per-dose compounded GLP-1 without subscriptions
Arc-1 offers compounded semaglutide (from $249.99) and compounded tirzepatide (from $299.99) as per-dose purchases, not monthly subscriptions. Longevity-focused platform also offering ED medication, B12, NAD+, Rapamycin, Sermorelin, and Metformin.
Medium confidence · Last verified 2026-04-10 via WebFetch · How we verify provider data
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The Bottom Line
Arc-1 is a solid telehealth option with balanced features and pricing.
Score Breakdown
Drugs Offered
Arc-1 prescribes the following GLP-1 medications. Tap a drug to read our clinical guide with FDA label info, dosing schedules, side effects, and trial data.
Pricing
| Dose | Form | Price/mo |
|---|---|---|
| Compounded Semaglutide 0.5mg | compounded | $250 |
| Compounded Semaglutide 1mg | compounded | $350 |
| Compounded Tirzepatide 2.5mg | compounded | $300 |
| Compounded Tirzepatide 5mg | compounded | $400 |
✓ Pros
- •Both compounded semaglutide and tirzepatide available
- •Per-dose purchasing — no subscription or membership required
- •25% off + free shipping promotional offer
- •Broader longevity formulary (Rapamycin, NAD+, Sermorelin)
✗ Cons
- •No visible LegitScript or PCAB accreditation
- •No legal entity name or address disclosed
- •State availability not disclosed
- •Pricing is per-dose not monthly — higher doses are very expensive ($1,085-$1,585 for semaglutide 1.75-2.5mg)
- •No named clinicians or pharmacy partners
Ready to start with Arc-1?
Starting at $250/month. See current pricing and start your free consultation.
Sources & methodology
Our Arc-1 review applies the same 6-dimension scoring framework we use for every provider. Pricing, FDA approval status, compounding rules, and clinical-trial efficacy claims are sourced from the primary regulatory and peer-reviewed literature below.
Sources & methodology — as of May 2026
- 1.Weight Loss Rankings — GLP-1 Pricing Index 2026 (our independent dataset)— WeightLossRankings.org.
- 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
- 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
- 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
- 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
- 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
- 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 9.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
- 10.FDA — Zepbound (tirzepatide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 11.FDA — Mounjaro (tirzepatide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 12.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Garvey WT et al.)— New England Journal of Medicine.PMID: 40334173.
Alternatives to Arc-1
Belle Health
Best for: Cost-sensitive patients comfortable with the Feb-2026 FDA warning, wanting flat-rate pricing and dietitian-included support
Editorial score · methodology
Editorial score · methodology
Frequently Asked Questions
Glossary references
Key terms in this article, linked to their canonical definitions.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Ready to start with Arc-1?
Starting at $250/month. See current pricing and start your free consultation.