He & She MD Review

He & She MD: a GLP-1 program you have to prepay

He & She MD is a nationwide cash-pay telehealth clinic built around one product line it calls the GLP-1 Platinum program. There is no month-to-month plan anymore, and the shortest term is three months, paid up front. On that plan, compounded injectable semaglutide costs $149 a month, and the per-month rate falls to $99 on the annual plan. Tirzepatide works the same way, $209 on three months falling to $159 on the annual plan. There are oral semaglutide and oral tirzepatide routes for people who would rather not handle a needle. The three-month semaglutide rate sits below the category median of $179, and you are only billed if a clinician actually prescribes you something.

How we get the category median: $179 is the middle value of the cheapest ongoing monthly price (not a first-month promo) at each of the 508 GLP-1 providers we track.

How the pricing actually works (and what the headline hides)

The number He & She MD advertises is a commitment price, not a monthly one. The injectable ladder has three rungs, three months, six months and annual, and the per-month rate drops at every step. Semaglutide runs $149, then $139, then $99. Tirzepatide runs $209, then $199, then $159. Every rung is prepaid for the whole term, so the cheapest advertised rate is also the largest single charge you will make. The oral programs list $209 a month to start for semaglutide, then $239, and $269 to start for tirzepatide, then $299. Neither oral card says how long the starting rate lasts or how the billing works. Budget for the rung you can actually afford rather than the sticker on the homepage.

• Annual: the lowest per-month rate at $99 for semaglutide, but the entire year is charged in one payment
• Six-month: the middle rung, at $139 for semaglutide or $199 for tirzepatide
• Three-month: the shortest commitment on offer, at $149 for semaglutide or $209 for tirzepatide
• Billing safeguard: no charge unless a clinician writes you a prescription, and the clinic states there are no membership fees

The homepage adds some noise. Its countdown banner says the offer has ended while still advertising the $99 rate. Its footnotes describe older starter rates that no longer match the plan cards. Go by the plans page instead, and confirm your rate at checkout before you pay.

The medications and who fills them

This is where He & She MD is more transparent than most. It offers compounded semaglutide and tirzepatide as injections or oral options. It also offers brand-name access to Ozempic, Wegovy and Zepbound for patients who want the FDA-approved finished products. The compounding is handled by two FDA-registered pharmacies the clinic discloses by name: F&F Pharmacies Inc (operating as Jungle Jims Pharmacy in Fairfield, Ohio) and Specialty Medical Drugstore LLC (operating as GoGoMeds). Its medical group is Wasef Health, PC. Naming the actual partners is a trust signal a lot of competitors skip. It lets you look up the supply chain yourself.

What you get besides the vial

Every plan bundles the things that usually carry separate fees elsewhere. Medication, injection supplies, free shipping, ongoing provider support and unlimited messaging are all included, and the Platinum program adds GLP-1-specific coaching with nutrition guidance plus in-app progress tracking. The messaging being unlimited matters in practice: you are not rationing questions or paying per follow-up when you need a dose adjustment or hit a side effect. For a first-time GLP-1 patient who wants hand-holding rather than a prescription dropped in the mail, that wraparound support is a real part of the value here.

Coverage and the fine print

He & She MD ships to 49 states and DC. The one hard exclusion is Louisiana, and it will not deliver to PO boxes anywhere, so a street address is required. It is a cash-pay operation, so you pay out of pocket. You can cancel at any time by email or from your account. Membership fees already paid are non-refundable, though, so canceling partway through a prepaid term does not bring money back.

Trust, oversight, and the honest caveat

He & She MD displays a LegitScript certification badge, and there are no FDA warning letters on file against it. Its pricing and pharmacy partners are published on its own site. The weak spot is the legal paperwork, because its terms of service read like an unedited template. They carry a placeholder where the support phone number should be, and they mention services this clinic does not sell. No support phone number is published at all; support runs through support@heandshemd.com. The other caveat, which the clinic itself states in its FDA disclaimer, is that compounded GLP-1s are not FDA-approved finished products. If an FDA-reviewed product matters to you, lean on the brand-name access rather than the compounded plans.

Who should choose it, and who should skip it

• Choose it if you can prepay at least three months and want a low per-month price, or want to pick between an injection and an oral option
• Choose it if you specifically want a provider that names its pharmacies and its medical group
• Skip it if you live in Louisiana, need to bill insurance, or only want FDA-approved brand medication and nothing compounded
• Skip it if you want to pay month to month, because no monthly plan is offered

Bottom line

He & She MD earns its spot on price, but only for patients who can commit. At $149 a month the three-month plan sits below the $179 category median, and the annual plan drops semaglutide to $99. Every injectable option is prepaid, and fees you have already paid do not come back if you cancel. It names its pharmacies, bundles coaching and unlimited clinician messaging, and charges you nothing unless you are actually prescribed. The template-style terms of service are a reason for some caution before you hand over a card. Go in clear-eyed about which rung you are buying, and confirm your rate at checkout. See how we weigh these factors in our scoring methodology.

Shopping around? AgelessRx ($139/month) and Gala ($149/month) are the nearest alternatives to He & She MD in our rankings.