He & She MD Review

He & She MD: a GLP-1 program that gets cheap only if you commit

He & She MD is a nationwide cash-pay telehealth clinic built around one product line it calls the GLP-1 Platinum program. Compounded injectable semaglutide costs $99 a month at its cheapest, but that rate is the annual plan, and the full year is charged as a single payment up front. Month to month, the same medication is $199. Tirzepatide works the same way, $299 monthly falling to $159 on the annual plan, and there is an oral semaglutide route for people who would rather not handle a needle. That bottom rung sits well under the category median of $169, and you are only billed if a clinician actually prescribes you something.

How the pricing actually works (and what the headline hides)

The number He & She MD advertises is a commitment price, not a monthly one. The ladder has four rungs — month to month, three months, six months, and annual — and the per-month rate drops at every step: semaglutide runs $199, then $149, then $139, then $99; tirzepatide runs $299, then $209, then $199, then $159. Every rung below month to month is prepaid for the whole term, so the cheapest advertised rate is also the largest single charge you will make. Separately, the homepage sells six-month starter rates that renew higher once the term is up. None of this is a teaser-then-cancel trap, but budget for the rung you can actually afford rather than the sticker on the homepage.

• Annual: the lowest per-month rate at $99, but the entire year is charged in one payment
• Six-month: the middle rung, and the term the homepage starter rates are tied to
• Month to month: no commitment at $199 for semaglutide or $299 for tirzepatide, the rate every other rung discounts from
• Billing safeguard: no charge unless a clinician writes you a prescription, and the clinic states there are no membership fees

The medications and who fills them

This is where He & She MD is more transparent than most. It offers compounded semaglutide and tirzepatide as injections, an oral semaglutide option, and brand-name access to Ozempic, Wegovy and Zepbound for patients who want the FDA-approved finished products. The compounding is handled by two named, FDA-registered pharmacies the clinic discloses by name: F&F Pharmacies Inc (operating as Jungle Jims Pharmacy in Fairfield, Ohio) and Specialty Medical Drugstore LLC (operating as GoGoMeds). Naming the actual pharmacy partners is a trust signal a lot of competitors skip, and it lets you verify the supply chain yourself.

What you get besides the vial

Every plan bundles the things that usually carry separate fees elsewhere. Medication, injection supplies, free shipping, ongoing provider support and unlimited messaging are all included, and the Platinum program adds GLP-1-specific coaching with nutrition guidance plus in-app progress tracking. The messaging being unlimited matters in practice: you are not rationing questions or paying per follow-up when you need a dose adjustment or hit a side effect. For a first-time GLP-1 patient who wants hand-holding rather than a prescription dropped in the mail, that wraparound support is a real part of the value here.

Coverage and the fine print

He & She MD ships to 49 states and DC. The one hard exclusion is Louisiana, and it will not deliver to PO boxes anywhere, so a street address is required. It is a cash-pay operation, meaning insurance billing is not part of the model, you pay out of pocket. That is standard for compounded-GLP-1 telehealth, but worth knowing if you were hoping to run this through a plan.

Trust, oversight, and the honest caveat

On the safety side, He & She MD is LegitScript-certified, which is the certification most serious telehealth pharmacies carry and a baseline most fly-by-night operations cannot pass. There are no FDA warning letters on file against it, and our verification confidence is high, the pricing and program details were live-confirmed from the company's own site and its disclosures are specific rather than vague. The honest caveat, which the clinic itself states in its FDA disclaimer, is that compounded GLP-1s are not FDA-approved finished products the way brand Ozempic or Zepbound are. That is a category-wide reality for compounded telehealth, not a He & She MD failing, but if having an FDA-reviewed product matters to you, lean on the brand-name access it offers rather than the compounded tiers.

Who should choose it, and who should skip it

• Choose it if you can prepay a full year and want the lowest per-month price, or want to pick between an injection and an oral tablet
• Choose it if you specifically want a provider that names its pharmacies and carries LegitScript certification
• Skip it if you live in Louisiana, need to bill insurance, or only want FDA-approved brand medication and nothing compounded
• Skip it if you cannot commit up front, because the month-to-month rate is roughly double the annual one

Bottom line

He & She MD earns its spot on price, but only for patients who can commit. At $99 a month the annual plan sits well below the $169 category median; at $199 month to month it is unremarkable, and the gap between those two numbers is the whole story. Either way it names its pharmacies, carries LegitScript certification, bundles coaching and unlimited clinician messaging, and charges you nothing unless you are actually prescribed. Go in clear-eyed about which rung of the ladder you are buying, and confirm your rate at checkout before you commit. See how we weigh these factors in our scoring methodology.

Shopping around? Sunlight ($88/month) and bmiMD ($99/month) are the nearest alternatives to He & She MD in our rankings.