StackMD Review
Semaglutide & tirzepatide GLP-1 weight-loss telehealth · Independently scored 7.5/10
Best for: shoppers who want an exact price for their specific dose before committing
StackMD is a solid telehealth option with balanced features and pricing.
What the monthly price covers
Medication
Included
Provider visits
Not disclosed
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
No insurance needed · Vetted by our editors
StackMD is a New York telehealth platform (Medical 360 HC PLLC) selling compounded semaglutide and tirzepatide, both formulated with B12 and glycine, alongside NAD+, sermorelin and other longevity peptides. It prices every dose strength openly instead of quoting one 'from' number: semaglutide runs $125 to $225 a month across five strengths and tirzepatide $199 to $449 across six. There are no membership fees, and prescribing is handled by its named partner SamaritanMD.
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Vetted alternatives to StackMD
Direct Meds
Best for: listed for transparent disclosure — see FDA warning and BBB complaint pattern before considering
Editorial score · methodology
Maximus
Best for: men seeking compounded GLP-1 alongside testosterone optimization
Editorial score · methodology
Sesame Care
Best for: Brand-name GLP-1s (Wegovy, Zepbound) at LillyDirect/NovoCare cash prices — no compounding
Editorial score · methodology
StackMD at a glance
- Type
- GLP-1 telehealth provider
- Medications
- Semaglutide, Tirzepatide
- Starting price
- $125/mo (Published per-dose ladder on /product/semaglutide-compounded-glp-1: 1mg $125, 2mg $149, 4mg $175, 6mg $199, 10mg $225 — all 1ml vials of semaglutide with B12 and glycine, billed as a monthly plan ('Plans starting at just $125/month'). No membership or platform fee on top.)
- Pricing model
- Scales with dose — higher doses cost more
- What's included
- Medication · Shipping
- Availability
- All 50 states
- FDA status
- No FDA warning letter on record
How we scored StackMD
Each dimension is scored algorithmically from StackMD’s real pricing, drugs offered, verification status, and disclosed inclusions — using the same six-dimension framework we apply to every provider.
Value25%
8.3/10At $125/mo, StackMD runs about 26% below the $169 median for GLP-1 providers. Note the price scales with dose, so budget for higher tiers as you titrate.
Effectiveness25%
7.8/10StackMD offers both semaglutide and tirzepatide — the two GLP-1 molecules with the strongest published weight-loss trial outcomes.
User Experience15%
6.9/10Online intake and platform experience; 8 platform features disclosed.
Trust & Safety15%
7.0/10Core details confirmed by our editors; no FDA warning letters on file (last checked 2026-07-24).
Accessibility10%
8.4/10StackMD treats patients in all 50 states. FSA/HSA cards are accepted.
Support10%
5.6/10StackMD provides standard clinician follow-up; no extended coaching or community program is disclosed.
Providers that don’t post pricing up front score lower on Value and carry a cost-transparency note in their review. Read the full methodology →
How we verified this StackMD review
Last checked July 2026- Confirmed current pricing across 2 dose/plan tiers
- Confirmed availability in all 50 states
- Confirmed what the monthly price does and doesn't include
- Checked the FDA warning-letter database for enforcement actions
- Walked the public intake/checkout flow on the provider's site
Pricing, availability, and compliance facts come from the provider's own site and primary regulatory records — see the sources below. Editorial confidence in this data: medium.
GLP-1 medications StackMD offers
Tap any medication to read our plain-English guide — how it works, dosing, side effects, and what the trials found.
Pricing
Prices re-verified
Published per-dose ladder on /product/semaglutide-compounded-glp-1: 1mg $125, 2mg $149, 4mg $175, 6mg $199, 10mg $225 — all 1ml vials of semaglutide with B12 and glycine, billed as a monthly plan ('Plans starting at just $125/month'). No membership or platform fee on top.
Published per-dose ladder on /product/tirzepatide-compounded-glp-1-gip: 5mg $199, 10mg $249, 15mg $299, 20mg $349, 25mg $399, 30mg $449 — all 2ml vials of tirzepatide with B12 and glycine. A patient titrated to a high dose pays more than double the advertised starting price.
Ready to get started?
Plans and promotions change often — check StackMD's current pricing and active discounts before you decide.
What we like
- Publishes an exact price for every dose strength rather than a single 'from' figure — semaglutide $125-$225, tirzepatide $199-$449
- Names both its legal entity (Medical 360 HC PLLC) and its prescribing telehealth partner, SamaritanMD
- No membership or platform fee — the medication price is the whole price
- States plainly that its compounded medications are 'not FDA-approved and have not been evaluated by the FDA for safety, efficacy, or quality'
- Telehealth offered in all 50 states per its terms, with free discreet shipping and FSA/HSA eligibility
- Discloses the full formulation, including the B12 and glycine compounded into both GLP-1s
Watch-outs
- All sales are final — 'No refunds are issued except as described below', and dispensed medication cannot be returned
- Compounding pharmacies are never named, only 'a licensed third-party pharmacy'
- Price rises steeply with dose: tirzepatide runs $199 at 5mg to $449 at 30mg
- Billing and refunds are handled by SamaritanMD — StackMD 'has no authority to issue refunds' on its behalf
- Terms impose binding arbitration in New York and waive jury trial and class-action participation
- Both GLP-1s are compounded with added B12 and glycine rather than the single active ingredient
- Availability of specific treatments may still vary by state despite the all-50-states claim
- No LegitScript certification or pharmacy accreditation displayed
Is StackMD worth it? Our verdict
StackMD positions itself around one thing: shoppers who want an exact price for their specific dose before committing. It runs $125/month — toward the affordable end of the market. It treats patients in all 50 states, so access isn't a barrier.
On top of the prescription itself, StackMD points to No membership fees, No insurance needed, and HSA/FSA eligible.
How much StackMD actually costs
- Compounded semaglutide — $125/month
- Compounded tirzepatide — $199/month
That puts StackMD below the roughly $169 median ongoing price across the GLP-1 providers we track — a real cost advantage.
For a direct comparison, Oak runs semaglutide and tirzepatide from $119/month — worth pricing against StackMD before you commit.
Medications: what StackMD prescribes
StackMD prescribes semaglutide (the active drug in Wegovy and Ozempic) and tirzepatide (the active drug in Zepbound and Mounjaro) — the two molecules with the strongest published weight-loss trial outcomes. These are dispensed as compounded formulations from a licensed pharmacy, which is how the price stays below brand-name pens. Compounded drugs aren't FDA-approved as finished products — the standard trade-off across the compounded-GLP-1 market.
Who StackMD is best for — and who should skip it
A good fit if you…
- are focused on the lowest ongoing monthly cost.
- live anywhere in the US and want guaranteed access.
Look elsewhere if you…
- specifically want an FDA-approved brand-name pen.
- need to bill insurance — like most of this market, it's cash-pay.
Trust, safety, and medical oversight
StackMD treats patients in all 50 states. We found no FDA warning letters on file for the provider. As with any compounded program, the most important step you can take is confirming which licensed pharmacy fills your prescription and what's in the formulation — we explain how in our scoring methodology.
Bottom line
StackMD earns its place on the shortlist mainly on price: at $125/month it's one of the more affordable ways to stay on a GLP-1, without obvious corners cut on access or oversight.
The Bottom Line
StackMD is a solid telehealth option with balanced features and pricing.
Ready to start with StackMD?
Starting at $125/month. See current pricing and start your free consultation.
StackMD might not be your best fit if…
We rank editorially, so here’s where a different provider we track may serve you better.
- If you want brand-name Ozempic, Wegovy, Mounjaro or Zepbound, consider GobyMeds.
- If the lowest possible monthly price is your top priority, consider Sesame Care (from $59/mo).
- If you want built-in coaching and behavior-change support, consider Found.
Frequently Asked Questions
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Sources
The primary regulatory filings and peer-reviewed studies cited throughout this StackMD review:
Sources & methodology — as of July 2026
- 1.Weight Loss Rankings — GLP-1 Pricing Index 2026 (our independent dataset)— WeightLossRankings.org.
- 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
- 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
- 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
- 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
- 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
- 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 9.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
- 10.FDA — Zepbound (tirzepatide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 11.FDA — Mounjaro (tirzepatide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 12.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Garvey WT et al.)— New England Journal of Medicine.PMID: 40334173.
See StackMD's current pricing
Plans start at $125/month. Start your free consultation to check eligibility and today's price.