Lean Rx Review
Best for: Patients wanting compounded GLP-1 in injectable, sublingual, or tablet form
Lean Rx is a Sacramento-based telehealth technology platform offering compounded GLP-1 weight loss medications. Patients complete an online medical history and a telehealth call with an independent licensed provider, who prescribes when appropriate, then receive medication shipped home. Lean Rx offers compounded semaglutide from $266 per month and tirzepatide from $399 per month, in injectable, sublingual, and tablet forms. It advertises upfront pricing with no hidden fees, and notes it is a technology platform, not a healthcare provider. No state list is published.
Medium confidence · Last verified 2026-06-04 · How we verify provider data
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The Bottom Line
Lean Rx is a solid telehealth option with balanced features and pricing.
Score Breakdown
Drugs Offered
Lean Rx prescribes the following GLP-1 medications. Tap a drug to read our clinical guide with FDA label info, dosing schedules, side effects, and trial data.
Pricing
| Dose | Form | Price/mo |
|---|---|---|
| Starting | compounded | $266 |
| Starting | compounded | $399 |
✓ Pros
- •Both semaglutide and tirzepatide offered
- •Three formulations: injectable, sublingual, and tablet
- •Upfront pricing with no hidden fees advertised
- •Semaglutide starts at a low $266/month
- •Telehealth call with a licensed provider before prescribing
✗ Cons
- •Compounded-only; no FDA-approved branded options
- •No published state availability list
- •Platform is technology only, not a healthcare provider itself
- •Provider credentials not detailed on site
Ready to start with Lean Rx?
Starting at $266/month. See current pricing and start your free consultation.
Sources & methodology
Our Lean Rx review applies the same 6-dimension scoring framework we use for every provider. Pricing, FDA approval status, compounding rules, and clinical-trial efficacy claims are sourced from the primary regulatory and peer-reviewed literature below.
Sources & methodology — as of June 2026
- 1.Weight Loss Rankings — GLP-1 Pricing Index 2026 (our independent dataset)— WeightLossRankings.org.
- 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
- 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
- 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
- 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
- 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
- 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 9.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
- 10.FDA — Zepbound (tirzepatide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 11.FDA — Mounjaro (tirzepatide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 12.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Garvey WT et al.)— New England Journal of Medicine.PMID: 40334173.
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Frequently Asked Questions
Glossary references
Key terms in this article, linked to their canonical definitions.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Ready to start with Lean Rx?
Starting at $266/month. See current pricing and start your free consultation.