Silhouette MD Review
Best for: people who want hands-on concierge support alongside compounded GLP-1 treatment
Concierge-style GLP-1 telehealth offering compounded semaglutide and tirzepatide in both injectable and oral forms, with provider oversight and full-service support included on every plan. Prescriptions are issued and fulfilled by licensed clinical partner OpenLoop Health.
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Not disclosed
Lab work
Not disclosed
Coaching
Billed separately
No insurance needed · Vetted by our editors
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The Bottom Line
Silhouette MD is a solid telehealth option with balanced features and pricing.
Silhouette MD at a glance
- Type
- GLP-1 telehealth provider
- Medications
- Semaglutide, Tirzepatide
- Starting price
- $149/mo (Lowest advertised tier ('as low as').)
- What's included
- Medication · Consult
- FDA status
- No FDA warning letter on record
How we scored Silhouette MD
Each dimension is scored algorithmically from Silhouette MD’s real pricing, drugs offered, verification status, and disclosed inclusions — using the same six-dimension framework we apply to every provider.
Value25%
7.9/10At $149/mo, Silhouette MD runs about 12% below the $170 median for GLP-1 providers.
Effectiveness25%
8.0/10Silhouette MD offers both semaglutide and tirzepatide — the two GLP-1 molecules with the strongest published weight-loss trial outcomes. An oral/needle-free option is offered for patients who avoid injections.
User Experience15%
6.9/10Online intake and platform experience — consult included in the price; 5 platform features disclosed.
Trust & Safety15%
7.1/10Core details confirmed by our editors; no FDA warning letters on file (last checked 2026-06-30).
Accessibility10%
5.9/10Silhouette MD's exact state footprint isn't published — confirm coverage in your state before signing up.
Support10%
5.3/10Coaching not included in the base price.
How we verified this Silhouette MD review
Last checked 2026-06-30- Confirmed current pricing across 4 dose/plan tiers
- Confirmed what the monthly price does and doesn't include
- Checked the FDA warning-letter database for enforcement actions
- Walked the public intake/checkout flow on the provider's site
Pricing, availability, and compliance facts come from the provider's own site and primary regulatory records — see the sources below. Editorial confidence in this data: medium.
GLP-1 medications Silhouette MD offers
Tap any medication to read our plain-English guide — how it works, dosing, side effects, and what the trials found.
Pricing
Lowest advertised tier ('as low as').
Lowest advertised tier ('as low as').
Oral formulation; lowest advertised tier.
Oral formulation; lowest advertised tier.
Ready to get started?
Plans and promotions change often — check Silhouette MD's current pricing and active discounts before you decide.
What we like
- Compounded semaglutide and tirzepatide in both injectable and oral formulations
- Concierge-level support — monitoring, expert guidance, and check-ins included on every plan
- Transparent, published pricing starting at $149/mo for semaglutide injection
- Prescriptions issued and fulfilled by licensed clinical partner OpenLoop Health
Watch-outs
- Tirzepatide ($299/mo) and oral options ($263–$325/mo) priced above many compounded competitors
- State availability not published
- Newer brand with limited independent review history
- Medications are compounded, not FDA-approved brand-name
Is Silhouette MD worth it? Our verdict
Silhouette MD positions itself around one thing: people who want hands-on concierge support alongside compounded GLP-1 treatment. It runs $149/month — toward the affordable end of the market. Its standout is a needle-free oral option, which very few providers offer.
How much Silhouette MD actually costs
- Compounded semaglutide — $149/month
- Compounded tirzepatide — $299/month
- Compounded semaglutide — $263/month
- Compounded tirzepatide — $325/month
That puts Silhouette MD below the roughly $170 median ongoing price across the GLP-1 providers we track — a real cost advantage.
Medications: what Silhouette MD prescribes
Silhouette MD prescribes semaglutide (the active drug in Wegovy and Ozempic) and tirzepatide (the active drug in Zepbound and Mounjaro) — the two molecules with the strongest published weight-loss trial outcomes. These are dispensed as compounded formulations from a licensed pharmacy, which is how the price stays below brand-name pens. Compounded drugs aren't FDA-approved as finished products — the standard trade-off across the compounded-GLP-1 market.
Silhouette MD's needle-free oral option is a real draw if you've been avoiding a GLP-1 because of injections. Just set expectations on the science: oral and buccal delivery of these peptides is far less studied than the injectable versions the trials used, so treat it as a convenience option rather than a proven equal to the shot.
Who Silhouette MD is best for — and who should skip it
A good fit if you…
- are focused on the lowest ongoing monthly cost.
- are needle-averse and want a non-injectable option.
Look elsewhere if you…
- specifically want an FDA-approved brand-name pen.
- need to bill insurance — like most of this market, it's cash-pay.
Trust, safety, and medical oversight
We found no FDA warning letters on file for the provider. As with any compounded program, the most important step you can take is confirming which licensed pharmacy fills your prescription and what's in the formulation — we explain how in our scoring methodology.
Bottom line
Silhouette MD earns its place on the shortlist mainly on price: at $149/month it's one of the more affordable ways to stay on a GLP-1, without obvious corners cut on access or oversight.
Ready to start with Silhouette MD?
Starting at $149/month. See current pricing and start your free consultation.
Alternatives to Silhouette MD
Enhance MD
Best for: lab-monitored compounded GLP-1 with mandatory video visit
Editorial score · methodology
Editorial score · methodology
Editorial score · methodology
Frequently Asked Questions
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Sources
The primary regulatory filings and peer-reviewed studies cited throughout this Silhouette MD review:
Sources & methodology — as of June 2026
- 1.Weight Loss Rankings — GLP-1 Pricing Index 2026 (our independent dataset)— WeightLossRankings.org.
- 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
- 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
- 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
- 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
- 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
- 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 9.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
- 10.FDA — Zepbound (tirzepatide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 11.FDA — Mounjaro (tirzepatide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 12.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Garvey WT et al.)— New England Journal of Medicine.PMID: 40334173.
Ready to start with Silhouette MD?
Starting at $149/month. See current pricing and start your free consultation.