Actin Review
Best for: affordable compounded semaglutide with B12 enhancement
Actin offers compounded semaglutide with B12 for weight loss. Also provides hormone, sexual wellness, and hair health treatments. Transparent pricing starting from $133.
Medium confidence · Last verified 2026-04-10 via manual · How we verify provider data
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The Bottom Line
Actin is a solid telehealth option with balanced features and pricing.
Score Breakdown
Drugs Offered
Actin prescribes the following GLP-1 medications. Tap a drug to read our clinical guide with FDA label info, dosing schedules, side effects, and trial data.
Pricing
| Dose | Form | Price/mo |
|---|---|---|
| Compounded GLP-1 (semaglutide + B12) | compounded | $133 |
✓ Pros
- •Semaglutide + B12 combination for added energy support
- •Transparent pricing — exact cost shown upfront with no hidden fees
- •Competitive starting price from $133
✗ Cons
- •Semaglutide only — no tirzepatide or liraglutide
- •No visible LegitScript or PCAB accreditation
- •State availability not disclosed
- •Broader platform (hormones, sexual wellness, hair health)
Ready to start with Actin?
Starting at $133/month. See current pricing and start your free consultation.
Sources & methodology
Our Actin review applies the same 6-dimension scoring framework we use for every provider. Pricing, FDA approval status, compounding rules, and clinical-trial efficacy claims are sourced from the primary regulatory and peer-reviewed literature below.
Sources & methodology — as of May 2026
- 1.Weight Loss Rankings — GLP-1 Pricing Index 2026 (our independent dataset)— WeightLossRankings.org.
- 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
- 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
- 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
- 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
- 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
- 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
Alternatives to Actin
Belle Health
Best for: Cost-sensitive patients comfortable with the Feb-2026 FDA warning, wanting flat-rate pricing and dietitian-included support
Editorial score · methodology
Editorial score · methodology
Frequently Asked Questions
Glossary references
Key terms in this article, linked to their canonical definitions.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Ready to start with Actin?
Starting at $133/month. See current pricing and start your free consultation.