Actin Review

Best for: affordable compounded semaglutide with B12 enhancement

Actin offers compounded semaglutide with B12 for weight loss. Also provides hormone, sexual wellness, and hair health treatments. Transparent pricing starting from $133.

By Eli Marsden · Founding Editor
Editorially reviewed (not clinically reviewed) · How we verify contentLast reviewed

Medium confidence · Last verified 2026-04-10 via manual · How we verify provider data

7.0
★★★★☆3.5
Compounded SemaglutideB12 Enhanced
$133/mo
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The Bottom Line

Actin is a solid telehealth option with balanced features and pricing.

Score: 7/10Best for: affordable compounded semaglutide with B12 enhancementFrom: $133/mo

Score Breakdown

Value
7
Effectiveness
7
User Experience
7
Trust & Safety
7
Accessibility
7
Support
7

Pricing

DoseFormPrice/mo
Compounded GLP-1 (semaglutide + B12)compounded$133

✓ Pros

  • •Semaglutide + B12 combination for added energy support
  • •Transparent pricing — exact cost shown upfront with no hidden fees
  • •Competitive starting price from $133

✗ Cons

  • •Semaglutide only — no tirzepatide or liraglutide
  • •No visible LegitScript or PCAB accreditation
  • •State availability not disclosed
  • •Broader platform (hormones, sexual wellness, hair health)

Ready to start with Actin?

Starting at $133/month. See current pricing and start your free consultation.

Visit Actin →

Sources & methodology

Our Actin review applies the same 6-dimension scoring framework we use for every provider. Pricing, FDA approval status, compounding rules, and clinical-trial efficacy claims are sourced from the primary regulatory and peer-reviewed literature below.

Sources & methodology — as of April 2026
  1. 1.Weight Loss Rankings — GLP-1 Pricing Index 2026 (our independent dataset)— WeightLossRankings.org.
  2. 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
  3. 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
  4. 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
  5. 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
  6. 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
  7. 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
  8. 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.

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Alan Meds

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Alloy

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Editorial score · methodology

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Frequently Asked Questions

Ready to start with Actin?

Starting at $133/month. See current pricing and start your free consultation.

Visit Actin →