Clume Health Review
Semaglutide & tirzepatide GLP-1 weight-loss telehealth · Independently scored 7.1/10
Best for: readers who want a separately priced microdose track and named dispensing pharmacies
Clume Health scores highest on the strength of its clinical program — drug options and dosing support.
Semaglutide
Tirzepatide
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
No insurance needed · Vetted by our editors
Clume Health sells compounded semaglutide and tirzepatide in oral and injectable form across three tiers: a full-dose Signature program from $259/mo, a Microdose/Maintain program from $219/mo, and an NAD+ and sermorelin longevity track. Its terms name four dispensing pharmacies outright, which most compounded sellers will not do. Clinical care runs through OpenLoop, and cheaper per-month rates are available only by prepaying a 12- or 52-week term.
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
Vetted alternatives to Clume Health
Telos Rx
Best for: Needle-free, microdosed compounded GLP-1 with lab-monitored care
Editorial score · methodology
Editorial score · methodology
RNK Health
Best for: compounded GLP-1 alongside NAD+, peptide and longevity add-ons
Editorial score · methodology
Clume Health at a glance
- Type
- GLP-1 telehealth provider
- Medications
- Semaglutide, Tirzepatide
- Starting price
- $219/mo (The $200/mo figure requires a 12-week prepaid term.)
- What's included
- Medication · Consult · Shipping
- FDA status
- No FDA warning letter on record
How we scored Clume Health
Each dimension is scored algorithmically from Clume Health’s real pricing, drugs offered, verification status, and disclosed inclusions — using the same six-dimension framework we apply to every provider.
Value25%
6.3/10At $219/mo, Clume Health runs about 30% above the $169 median for GLP-1 providers.
Effectiveness25%
8.3/10Clume Health offers both semaglutide and tirzepatide — the two GLP-1 molecules with the strongest published weight-loss trial outcomes. An oral/needle-free option is offered for patients who avoid injections.
User Experience15%
7.2/10Online intake and platform experience — consult included in the price; 5 platform features disclosed.
Trust & Safety15%
7.4/10Core details confirmed by our editors; no FDA warning letters on file (last checked 2026-08-20).
Accessibility10%
6.2/10Clume Health's exact state footprint isn't published — confirm coverage in your state before signing up.
Support10%
6.0/10Clume Health provides standard clinician follow-up; no extended coaching or community program is disclosed.
Providers that don’t post pricing up front score lower on Value and carry a cost-transparency note in their review. Read the full methodology →
How we verified this Clume Health review
Last checked August 2026- Confirmed current pricing across 4 dose/plan tiers
- Confirmed what the monthly price does and doesn't include
- Checked the FDA warning-letter database for enforcement actions
- Walked the public intake/checkout flow on the provider's site
Pricing, availability, and compliance facts come from the provider's own site and primary regulatory records — see the sources below. Editorial confidence in this data: medium.
What to expect when you sign up with Clume Health
We walked Clume Health’s public signup flow in August 2026 to document the process — the steps, pricing transparency, and what’s required — before you commit. (We don’t create accounts, enter medical information, or check out; this is the observable funnel, not a prescribing outcome.)
- 1Start Your Program lists three tiers side by side with prices visible before any question is asked.
- 2Choosing Signature hands off to a separate host, intake.clumehealth.com, with a seven-step progress bar.
- 3Step one promises "a quick quiz about your medical history, then your personalized treatment options" and a free assessment.
- 4Step two asks for height and weight, then computes and displays a BMI immediately.
- 5Step three asks for a weight-loss goal and motivations, then runs an evaluation animation and projects a three-month weight target with a not-guaranteed disclaimer.
- 6Step four asks where to send the quiz results and requires agreeing to OpenLoop's Telehealth Consent, Terms of Use and Notice of Privacy Practices to continue.
- 7We stopped at that consent gate. Email is genuinely optional — the page offers "You can also proceed without email for now" — but the consent tick is not.
- The three program prices are public, which is better than the many sellers that reveal nothing before intake.
- But the homepage and the program page disagree: the homepage says "starting at *$199/month" for GLP-1 and microdose programs, while the cheapest such program is $259/mo month-to-month.
- The homepage's "*$159/month" for the longevity track is likewise below its real $216/mo price, and neither asterisk resolves to a footnote.
- Each tier advertises a second, lower monthly figure that is only available by prepaying a 12- or 52-week term.
- The weight projection carries an honest disclaimer: "Results are not guaranteed and may vary by individual."
- Marketing email consent is a separate, unticked box rather than being bundled into the required consent.
Clume Health customer support
GLP-1 medications Clume Health offers
Tap any medication to read our plain-English guide — how it works, dosing, side effects, and what the trials found.
Pricing
Prices re-verified
The $186/mo figure is a 52-week prepaid term, not an ongoing monthly rate.
The $186/mo figure is a 52-week prepaid term, not an ongoing monthly rate.
The $200/mo figure requires a 12-week prepaid term.
The $200/mo figure requires a 12-week prepaid term.
Ready to get started?
Plans and promotions change often — check Clume Health's current pricing and active discounts before you decide.
What we like
- Names four dispensing pharmacies in its terms, a level of disclosure most compounded sellers avoid.
- Offers both full-dose and microdose tracks, so maintenance has its own priced program.
- Sells semaglutide and tirzepatide in oral as well as injectable form.
- Lists what the monthly price covers, including consultation, medication and at-home delivery.
- Cancellation is allowed at any time by email or through the patient portal.
Watch-outs
- The homepage advertises "starting at *$199/month" and "*$159/month", but no program is priced at either figure.
- Those asterisks lead to no footnote anywhere on the page.
- The cheapest advertised rates require prepaying a full term — $186/mo means a 52-week commitment.
- Canceling needs 72 hours' notice before the next billing date or you are charged for that cycle.
- No refund is issued for the month in which you cancel, or for any prior month.
- Personalized options appear only after you accept OpenLoop's telehealth consent.
- No LegitScript seal or other verified trust badge appears anywhere on the site.
- Support is email only; no phone number or published hours.
Is Clume Health worth it? Our verdict
Clume Health positions itself around one thing: readers who want a separately priced microdose track and named dispensing pharmacies. It runs $219/month — a premium to the category, so the extras need to justify it. Its standout is a needle-free oral option, which very few providers offer.
Clume Health rounds out its offering with Microdosing and Oral or injectable.
How much Clume Health actually costs
- Compounded semaglutide — $259/month
- Compounded tirzepatide — $259/month
- Compounded semaglutide — $219/month
- Compounded tirzepatide — $219/month
For context, the typical ongoing price across the GLP-1 providers we track is around $169/month, so Clume Health's standing rate sits at the premium end.
For a direct comparison, PeterMD runs semaglutide and tirzepatide from $215.67/month — worth pricing against Clume Health before you commit.
Medications: what Clume Health prescribes
Clume Health prescribes semaglutide (the active drug in Wegovy and Ozempic) and tirzepatide (the active drug in Zepbound and Mounjaro) — the two most-studied weight-loss molecules on the market today. The medication is compounded at a licensed pharmacy rather than sold as a brand pen, which is what keeps the price down. The trade-off is the one every compounded provider shares: compounded drugs aren't FDA-approved as finished products.
Clume Health's needle-free oral option is a real draw if you've been avoiding a GLP-1 because of injections. Just set expectations on the science: oral and buccal delivery of these peptides is far less studied than the injectable versions the trials used, so treat it as a convenience option rather than a proven equal to the shot.
Who Clume Health is best for — and who should skip it
A good fit if you…
- are needle-averse and want a non-injectable option.
Look elsewhere if you…
- want the lowest total cost over 6–12 months — a flat-rate provider like Sunlight will likely beat the ongoing price.
- specifically want an FDA-approved brand-name pen.
- need to bill insurance — like most of this market, it's cash-pay.
Trust, safety, and medical oversight
We found no FDA warning letters on file for the provider. As with any compounded program, the most important step you can take is confirming which licensed pharmacy fills your prescription and what's in the formulation — we explain how in our scoring methodology.
Bottom line
Clume Health costs more than the budget end of the market, so it makes the most sense if its specific extras — the oral option especially matter to you. If they don't, you can likely get the same medication for less elsewhere. If you're comparison-shopping, MadeMed is one of the closest alternatives we track — worth a look before deciding.
The Bottom Line
Clume Health scores highest on the strength of its clinical program — drug options and dosing support.
Ready to start with Clume Health?
Starting at $219/month. See current pricing and start your free consultation.
Clume Health might not be your best fit if…
We rank editorially, so here’s where a different provider we track may serve you better.
- If you want brand-name Ozempic, Wegovy, Mounjaro or Zepbound, consider GobyMeds.
- If the lowest possible monthly price is your top priority, consider Sunlight (from $88/mo).
- If you want built-in coaching and behavior-change support, consider RNK Health.
Frequently Asked Questions
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Sources
The primary regulatory filings and peer-reviewed studies cited throughout this Clume Health review:
Sources & methodology — as of August 2026
- 1.Weight Loss Rankings — GLP-1 Pricing Index 2026 (our independent dataset)— WeightLossRankings.org.
- 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
- 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
- 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
- 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
- 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
- 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 9.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
- 10.FDA — Zepbound (tirzepatide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 11.FDA — Mounjaro (tirzepatide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 12.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Garvey WT et al.)— New England Journal of Medicine.PMID: 40334173.
See Clume Health's current pricing
Plans start at $219/month. Start your free consultation to check eligibility and today's price.