Medsol RX Review
Semaglutide & tirzepatide GLP-1 weight-loss telehealth · Independently scored 7.4/10
Best for: flexible, HSA/FSA-eligible compounded GLP-1 plans with a care coach
Medsol RX scores highest on state availability and ease of access.
Semaglutide
Tirzepatide
then $259/mo ongoing
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Included
No insurance needed · Vetted by our editors
Medsol RX is a GLP-1 weight-loss telehealth program with prescribing by OpenLoop clinicians. Month-to-month compounded semaglutide is $199/mo ($169 first month), tirzepatide is $259/mo ($239 first month), and oral semaglutide is $179/mo, with lower rates on 3-, 6- and 12-month plans; microdosing is $149/mo. Every plan includes a dedicated care coach, medical oversight and shipping, and it is HSA/FSA eligible with Klarna financing.
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Medsol RX at a glance
- Type
- GLP-1 telehealth provider
- Medications
- Semaglutide, Tirzepatide, Oral semaglutide
- Starting price
- $179/mo (see plan details)
- What's included
- Medication · Consult · Shipping · Coaching
- Availability
- All 50 states
- FDA status
- No FDA warning letter on record
How we scored Medsol RX
Each dimension is scored algorithmically from Medsol RX’s published pricing, drugs offered, verification status, and disclosed inclusions, using the same six-dimension framework we apply to every provider.
Value25%
7.0/10At $179/mo (see plan details), Medsol RX runs in line with the $179 median for GLP-1 providers (each program's lowest listed ongoing monthly price for compounded semaglutide).
Effectiveness25%
8.0/10Medsol RX offers both semaglutide and tirzepatide, the two GLP-1 molecules with the strongest published weight-loss trial outcomes. FDA-approved brand options are available alongside compounded versions. An oral/needle-free option is offered for patients who avoid injections.
User Experience15%
6.9/10Online intake and platform experience (consult included in the price); 8 platform features disclosed.
Trust & Safety15%
6.8/10Core details confirmed by our editors; no FDA warning letters on file.
Accessibility10%
8.2/10Medsol RX treats patients in all 50 states. FSA/HSA cards are accepted.
Support10%
7.3/10Coaching/dietitian access included.
Each checked against the provider’s own site.
Providers that don’t post pricing up front score lower on Value and carry a cost-transparency note in their review. Read the full methodology →
How we verified this Medsol RX review
Last checked October 2026- Confirmed current pricing across 7 dose/plan tiers
- Confirmed availability in all 50 states
- Confirmed what the monthly price does and doesn't include
- Checked the FDA warning-letter database for enforcement actions
- Walked the public intake/checkout flow on the provider's site
Pricing, availability, and compliance facts come from the provider's own site and primary regulatory records. See the sources below. Editorial confidence in this data: medium.
What we checked
- Provider's own pricing page
- $149–$1,399/mo across 7 dose/plan tiers (checked October 2026)
- FDA warning-letter register
- No letter on file for this provider
What to expect when you sign up with Medsol RX
We walked Medsol RX’s public signup flow in July 2026 to document the process (the steps, pricing transparency, and what’s required) before you commit. (We don’t create accounts, enter medical information, or check out; this is the observable funnel, not a prescribing outcome.)
- 1Take a free assessment that takes under 5 minutes.
- 2A licensed provider builds a custom treatment plan from your assessment.
- 3If prescribed, medication is shipped to your door.
- 4A personal care coach and 24/7 support are included.
- Prices are shown before intake: semaglutide $199/mo month to month ($169 first month), as low as $129/mo on a 12-month plan; tirzepatide $259/mo, or $199/mo on a 12-month plan.
- No insurance required and plans are HSA/FSA eligible.
- A free personal care coach and '24/7 Support & Guidance' are advertised.
- Medications are described as made in the USA.
- The site does not explicitly state whether labs or a video visit are required.
Medsol RX customer support
- Phone
- 252-419-4440
GLP-1 medications Medsol RX offers
Tap any medication to read our plain-English guide: how it works, dosing, side effects, and what the trials found.
Pricing
Prices re-verified
Month-to-month: $169 first month, then $199/mo. Longer plans: 3-mo $169/mo ($507), 6-mo $149/mo ($894), 12-mo $129/mo ($1,548).
Month-to-month $179/mo. Longer plans: 3-mo $159/mo ($477), 6-mo $139/mo ($834), 12-mo $119/mo ($1,428).
Every microdosing option is $149/mo, coaching included.
Month-to-month: $239 first month, then $259/mo. Longer plans: 3-mo $229/mo ($687), 6-mo $209/mo ($1,254), 12-mo $199/mo ($2,388).
Every microdosing option is $149/mo, coaching included.
$1,229/mo, same price every month, coaching included.
$1,399/mo, same price every month, coaching included.
Ready to get started?
Plans and promotions change often, so check Medsol RX's current pricing and active discounts before you decide.
What we like
- Month-to-month compounded semaglutide at $199/mo ($169 first month) with no long-term commitment required
- Clear plan tables with 3-, 6- and 12-month rates down to $129/mo (semaglutide) and $199/mo (tirzepatide)
- Every plan includes a dedicated care coach, custom treatment plan, medical oversight and shipping
- Oral semaglutide, $149/mo microdosing and brand-name Ozempic or Zepbound pens are also offered
- Names its partner pharmacies in its terms; HSA/FSA eligible with Klarna financing
Watch-outs
- Monthly charges are non-refundable once billed; cancel at least 72 hours before your next billing date
- Doesn't say which of its four partner pharmacies fills your prescription
- No legal entity name published on the site (only "Medsol RX", headquartered in Florida)
- Shows a "LegitScript Approved" label but no verifiable LegitScript seal
- The best per-month prices require paying 3, 6 or 12 months upfront
- Compounded GLP-1s are not FDA-approved (the site discloses this)
Is Medsol RX worth it?
Medsol RX built its program around one core idea: flexible, HSA/FSA-eligible compounded GLP-1 plans with a care coach. New patients start at $169/month for the first month, but the price steps up to $179/month (see plan details) once that window ends, so treat the headline number as an intro offer, not the standing rate. Its standout is a needle-free oral option, which very few providers offer.
Medsol RX offers a microdosing option. It also takes HSA/FSA payment and includes coaching or dietitian support.
How much Medsol RX costs
- Compounded semaglutide starts at $169 for the first month, then $199/month after that, at that tier.
- Compounded tirzepatide starts at $239 for the first month, then $259/month after that, for that option.
- Brand-name semaglutide runs $1229/month (see plan details), if you go that route.
- Brand-name tirzepatide runs $1399/month (see plan details), at that tier.
Because Medsol RX's headline figure is a see plan details, we don't set it against the roughly $179 market median for this category. That median is each program's lowest listed ongoing monthly price for compounded semaglutide, so compare Medsol RX with the month-to-month prices of the alternatives below instead.
MadeMed (about $179/month) is one of the closest alternatives to weigh Medsol RX against.
Medications: what Medsol RX prescribes
Medsol RX prescribes semaglutide (the active drug in Wegovy and Ozempic) and tirzepatide (the active drug in Zepbound and Mounjaro), the two most-studied weight-loss molecules on the market today. Pick the brand-name pen for the FDA-approved product, or the compounded version to cut the monthly cost, with the trade-off that a compounded drug isn't FDA-approved as a finished formulation.
Medsol RX's needle-free oral option appeals if you've been avoiding a GLP-1 because of injections. Just set expectations on the science: oral and buccal delivery of these peptides is far less studied than the injectable versions the trials used. Treat it as a convenience option, not a proven equal to the shot.
Who Medsol RX is best for, and who should skip it
A good fit if you…
- want the cheapest possible way to start a GLP-1 and see how you respond before committing.
- are needle-averse and want a non-injectable option, since the oral route skips the weekly injection most GLP-1 programs require.
- want coaching and follow-up built into the price already, instead of sold separately as an upsell.
- live anywhere in the US and want the certainty that your state is already covered.
Look elsewhere if you…
- need to bill insurance, since like most of this market it's cash-pay with no claims filed on your behalf.
Trust, safety, and medical oversight
Medsol RX treats patients in all 50 states, and we found no FDA warning letter on file for it. As with any compounded program, the most important step you can take is confirming which licensed pharmacy fills your prescription and what's in the formulation, and we explain how in our scoring methodology.
Bottom line
Medsol RX is one of the easiest ways to start a GLP-1 cheaply, as long as you go in knowing that the $169 intro price steps up to $179/month (see plan details) once the first month is behind you. Use that window to confirm the medication works for you, then re-check the ongoing math before you settle in.
The Bottom Line
Medsol RX scores highest on state availability and ease of access.
Ready to start with Medsol RX?
From $179/mo (see plan details). See current pricing and start your free consultation.
Head-to-head
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Medsol RX scores7.4/10
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Scores are our independent editorial ratings out of 10.
Frequently Asked Questions
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Sources
The primary regulatory filings and peer-reviewed studies cited throughout this Medsol RX review:
Sources & methodology (as of October 2026)
- 1.Weight Loss Rankings — GLP-1 Pricing Index 2026 (our independent dataset)— WeightLossRankings.org.
- 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
- 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
- 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
- 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
- 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
- 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 9.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
- 10.FDA — Zepbound (tirzepatide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 11.FDA — Mounjaro (tirzepatide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 12.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Garvey WT et al.)— New England Journal of Medicine.PMID: 40334173.
See Medsol RX's current pricing
Plans from $179/mo (see plan details). Start your free consultation to check eligibility and today's price.