Medsol RX Review
Semaglutide & tirzepatide GLP-1 weight-loss telehealth · Independently scored 7.3/10
Best for: shoppers who want flexible, HSA/FSA-eligible compounded GLP-1 plans with a care coach
Medsol RX scores highest on state availability and ease of access.
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Included
No insurance needed · Vetted by our editors
Medsol RX is a GLP-1 weight-loss telehealth program offering compounded semaglutide (from $209/mo) and tirzepatide, prescribed by board-certified clinicians via OpenLoop and shipped nationwide. Plans bundle the medication with a dedicated care coach, custom treatment plan, and medical oversight; it's HSA/FSA eligible with Klarna financing and offers month-to-month or 3/6/12-month options, plus microdosing and wellness add-ons.
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Medsol RX at a glance
- Type
- GLP-1 telehealth provider
- Medications
- Semaglutide, Tirzepatide
- Starting price
- $209/mo (12-mo plan; $229 (6-mo), $249 (3-mo), or $199 first month then $279 month-to-month)
- What's included
- Medication · Consult · Shipping · Coaching
- Availability
- All 50 states
- FDA status
- No FDA warning letter on record
How we scored Medsol RX
Each dimension is scored algorithmically from Medsol RX’s real pricing, drugs offered, verification status, and disclosed inclusions — using the same six-dimension framework we apply to every provider.
Value25%
6.5/10At $209/mo, Medsol RX runs about 24% above the $169 median for GLP-1 providers.
Effectiveness25%
7.8/10Medsol RX offers both semaglutide and tirzepatide — the two GLP-1 molecules with the strongest published weight-loss trial outcomes.
User Experience15%
7.1/10Online intake and platform experience — consult included in the price; 7 platform features disclosed.
Trust & Safety15%
7.0/10Core details confirmed by our editors; no FDA warning letters on file (last checked 2026-08-02).
Accessibility10%
8.4/10Medsol RX treats patients in all 50 states. FSA/HSA cards are accepted.
Support10%
7.5/10Coaching/dietitian access included.
Providers that don’t post pricing up front score lower on Value and carry a cost-transparency note in their review. Read the full methodology →
How we verified this Medsol RX review
Last checked August 2026- Confirmed current pricing across 2 dose/plan tiers
- Confirmed availability in all 50 states
- Confirmed what the monthly price does and doesn't include
- Checked the FDA warning-letter database for enforcement actions
- Walked the public intake/checkout flow on the provider's site
Pricing, availability, and compliance facts come from the provider's own site and primary regulatory records — see the sources below. Editorial confidence in this data: medium.
What to expect when you sign up with Medsol RX
We walked Medsol RX’s public signup flow in July 2026 to document the process — the steps, pricing transparency, and what’s required — before you commit. (We don’t create accounts, enter medical information, or check out; this is the observable funnel, not a prescribing outcome.)
- 1Take a free assessment that takes under 5 minutes.
- 2A licensed provider builds a custom treatment plan from your assessment.
- 3If prescribed, medication is shipped to your door.
- 4A personal care coach and 24/7 support are included.
- Monthly prices are shown before intake: Semaglutide from $169/mo, Tirzepatide from $239/mo, with bundle discounts ($249/$229/$209 for 3/6/12-month plans).
- No insurance required and plans are HSA/FSA eligible.
- A free personal care coach and '24/7 Support & Guidance' are advertised.
- Medications are described as made in the USA.
- The site does not explicitly state whether labs or a video visit are required.
Medsol RX customer support
- Phone
- 252-419-4440
GLP-1 medications Medsol RX offers
Tap any medication to read our plain-English guide — how it works, dosing, side effects, and what the trials found.
Pricing
Prices re-verified
12-mo plan; $229 (6-mo), $249 (3-mo), or $199 first month then $279 month-to-month
From ~$250/mo compounded; varies by dose
Ready to get started?
Plans and promotions change often — check Medsol RX's current pricing and active discounts before you decide.
What we like
- Compounded semaglutide from $209/mo (12-mo plan) and tirzepatide from ~$250/mo; HSA/FSA eligible with Klarna financing
- Every plan bundles the medication, a dedicated care coach, custom treatment plan, medical oversight, and free shipping
- Board-certified clinicians via OpenLoop; same-day approvals; ships nationwide
- Month-to-month option ($199 first month) with no long-term commitment, plus microdosing and wellness add-ons
Watch-outs
- Doesn't name its compounding pharmacy (generic 'certified U.S. pharmacies')
- No legal entity name published on the site
- Tirzepatide pricing is given as a range ($250-$1,400/mo), not a fixed rate
- Compounded GLP-1s are not FDA-approved (the site discloses this)
Is Medsol RX worth it? Our verdict
Medsol RX positions itself around one thing: shoppers who want flexible, HSA/FSA-eligible compounded GLP-1 plans with a care coach. It runs $209/month — a premium to the category, so the extras need to justify it. Coaching and follow-up are part of the package, not an upsell.
On top of the prescription itself, Medsol RX points to Microdosing, HSA/FSA eligible, and Ships nationwide.
How much Medsol RX actually costs
- Compounded semaglutide — $209/month
- Compounded tirzepatide — $250/month
For context, the typical ongoing price across the GLP-1 providers we track is around $169/month, so Medsol RX's standing rate sits at the premium end.
For a direct comparison, Maximus runs semaglutide and tirzepatide from $199.99/month — worth pricing against Medsol RX before you commit.
Medications: what Medsol RX prescribes
Medsol RX prescribes semaglutide (the active drug in Wegovy and Ozempic) and tirzepatide (the active drug in Zepbound and Mounjaro) — the two most-studied weight-loss molecules on the market today. The medication is compounded at a licensed pharmacy rather than sold as a brand pen, which is what keeps the price down. The trade-off is the one every compounded provider shares: compounded drugs aren't FDA-approved as finished products.
Who Medsol RX is best for — and who should skip it
A good fit if you…
- want coaching and follow-up included, not sold separately.
- live anywhere in the US and want guaranteed access.
Look elsewhere if you…
- want the lowest total cost over 6–12 months — a flat-rate provider like bmiMD will likely beat the ongoing price.
- specifically want an FDA-approved brand-name pen.
- need to bill insurance — like most of this market, it's cash-pay.
Trust, safety, and medical oversight
Medsol RX treats patients in all 50 states. We found no FDA warning letters on file for the provider. As with any compounded program, the most important step you can take is confirming which licensed pharmacy fills your prescription and what's in the formulation — we explain how in our scoring methodology.
Bottom line
Medsol RX costs more than the budget end of the market, so it makes the most sense if its specific extras matter to you. If they don't, you can likely get the same medication for less elsewhere.
The Bottom Line
Medsol RX scores highest on state availability and ease of access.
Ready to start with Medsol RX?
Starting at $209/month. See current pricing and start your free consultation.
Medsol RX might not be your best fit if…
We rank editorially, so here’s where a different provider we track may serve you better.
- If you want brand-name Ozempic, Wegovy, Mounjaro or Zepbound, consider GobyMeds.
- If the lowest possible monthly price is your top priority, consider Sesame Care (from $59/mo).
Frequently Asked Questions
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Sources
The primary regulatory filings and peer-reviewed studies cited throughout this Medsol RX review:
Sources & methodology — as of August 2026
- 1.Weight Loss Rankings — GLP-1 Pricing Index 2026 (our independent dataset)— WeightLossRankings.org.
- 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
- 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
- 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
- 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
- 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
- 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 9.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
- 10.FDA — Zepbound (tirzepatide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 11.FDA — Mounjaro (tirzepatide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 12.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Garvey WT et al.)— New England Journal of Medicine.PMID: 40334173.
See Medsol RX's current pricing
Plans start at $209/month. Start your free consultation to check eligibility and today's price.