Semaglutide in Missouri: Best Providers & Prices (2026)
Compare 50 Semaglutide telehealth providers available in Missouri, sorted by cheapest monthly price.
50 licensed telehealth providers ship compounded Semaglutide to Missouri addresses, with monthly prices averaging $199 — a roughly 85% discount to brand-name Wegovy at $1,349/month[3]. Missouri's adult obesity rate of 35% (#13 nationally) has driven the state into one of the country's most active cash-pay GLP-1 markets.
Missouri Medicaid & brand-name Wegovy: diabetes only[4]. Compounded semaglutide is typically cash-pay — it isn't covered by Medicaid, Medicare, or commercial insurance in most cases. Brand-name Wegovy is generally FSA/HSA eligible with a prescription, and many plan administrators also accept compounded GLP-1s as an FSA/HSA expense with a Letter of Medical Necessity[5]. At the median compounded price, switching from brand-name Wegovy would save roughly $13,800/year out of pocket, with providers shipping statewide from Kansas City to smaller towns.
Sources & methodology — as of May 2026
- 1.Weight Loss Rankings — GLP-1 Pricing Index 2026 (our independent dataset)— WeightLossRankings.org.
- 2.CDC BRFSS — Adult Obesity Prevalence Maps by State (Behavioral Risk Factor Surveillance System)— Centers for Disease Control and Prevention.
- 3.NovoCare — Wegovy cash-pay and savings program— Novo Nordisk (NovoCare).
- 4.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
- 5.IRS Publication 502 — Medical and Dental Expenses (HSA/FSA eligibility)— Internal Revenue Service.
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Semaglutide Providers Available in Missouri
Calibrate Health
Best for: patients with insurance coverage who want a year-long coaching-wrap around branded Wegovy / Zepbound / Foundayo
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Ondra Health
Best for: Cost-sensitive patients who want the lowest compounded-GLP-1 monthly cost and are willing to commit quarterly.
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Maves (Homera Health)
Best for: Performance-oriented buyers (men's health + body optimization framing) seeking aggressive first-month pricing ($99/mo semaglutide intro) with a verifiable LegitScript ID, all-50-state coverage, and brand-plus-parent corporate disclosure (Maves under Homera Health). Strong fit for buyers who prioritize transparency signals (verifiable LegitScript ID + verbatim FDA disclaimer) over named pharmacy partners.
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Vitara RX
Best for: Cost-sensitive patients seeking the lowest flat-rate compounded GLP-1 pricing from a LegitScript-certified marketplace with a named 503A pharmacy, who are comfortable with a marketplace model lacking a named medical director and a strict no-refunds policy.
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Elara Health and Wellness
Best for: Patients seeking a physician-guided bundled-care GLP-1 program (medication + quarterly labs + physician visits + coaching + 24/7 messaging at a single monthly price) with maximum pharmacy-partner transparency (four named 503A pharmacies disclosed) and clear corporate accountability (JTE Medical, LLC named parent). Strong fit for buyers who want more than transactional Rx access but don't need the unlimited-primary-care scope of true DPC models.
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Gimme Care
Best for: affordable compounded GLP-1 with nationwide coverage and microdose options
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Fresh Day Meds
Best for: Price-sensitive patients seeking the lowest-cost compounded semaglutide or tirzepatide from a LegitScript-certified, HIPAA-compliant multi-product telehealth platform with publicly disclosed Texas corporate headquarters, who don't require a named pharmacy partner or brand-name GLP-1 fallback.
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PeterMD
Best for: men seeking flat-priced compounded GLP-1 access alongside TRT or peptide therapy
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Curex
Best for: affordable compounded GLP-1 with strong corporate transparency and pharmacy testing
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Nalena
Best for: Women seeking transparent low-entry-price ($149/mo) compounded semaglutide or tirzepatide on a GLP-1-only platform with no membership fees, no hidden costs, money-back guarantee, and free 2-day shipping. Not recommended for patients who require brand-name FDA-approved GLP-1s — Nalena is compounded-only.
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PlushCare
Best for: readers who want a primary-care relationship with GLP-1 prescribing as one option, AND who read the class-action disclosure and verify the cancellation flow before subscribing
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Precision Telemed
Best for: transparent month-to-month compounded GLP-1 with pharmacy quality documentation
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Tyde Wellness
Best for: Cash-pay patients wanting transparent compounded-GLP-1 pricing with named, LegitScript-certified pharmacy fulfillment and the option to bundle menopause/HRT, hair loss, or longevity peptides through a single 50-state provider.
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Vytora Health
Best for: Patients seeking month-to-month or 3-month-bundle compounded semaglutide or tirzepatide with the option of brand-name Mounjaro/Zepbound on a single LegitScript-approved + HIPAA-compliant platform with named pharmacy partners and transparent operating-PC disclosure. Particularly suited for patients in KS, LA, MS, NM, WV where Vytora's audio-visit option satisfies state telehealth compliance.
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MEDVi
Best for: patients who want the option to switch between compounded and brand-name GLP-1 through one provider
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BetterMe Rx
Best for: patients who value pharmacy transparency — six named compounding partners
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InstaRX
Best for: Patients in any of the 50 states or DC seeking a multi-product compounded-medication telehealth platform (GLP-1 + peptides + sexual health) where they prefer to complete an intake to see pricing rather than comparing public per-dose tiers. NOT recommended for patients who require transparent upfront pricing, named pharmacy-partner disclosure, or visible LegitScript/HIPAA accreditation before committing to an intake.
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NiceRx
Best for: patients seeking batch-tested compounded GLP-1 with transparent entity disclosure
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Zealthy
Best for: not currently recommended — listed for transparency and reader awareness only
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Semaglutide Cost Breakdown in Missouri
Brand-name Wegovy retails for about $1349/mo without insurance. Here's how much each Semaglutide provider charges in Missouri, and how much you save vs the brand cash price.
| Provider | Min/mo | Max/mo | Savings vs Wegovy |
|---|---|---|---|
| Calibrate Health | $25 | $199 | Save $1324/mo |
| FitRx | $25 | $151 | Save $1324/mo |
| Maximus | $80 | $99 | Save $1269/mo |
| Ondra Health | $93 | $149 | Save $1256/mo |
| Lavender Sky Health | $95 | $95 | Save $1254/mo |
| Alan Meds | $99 | $158 | Save $1250/mo |
| Maves (Homera Health) | $99 | $124 | Save $1250/mo |
| Strut Health | $99 | $149 | Save $1250/mo |
| Trimi Health | $99 | $99 | Save $1250/mo |
| Vitara RX | $99 | $99 | Save $1250/mo |
| AmberHealth | $100 | $100 | Save $1249/mo |
| NewSelf | $100 | $135 | Save $1249/mo |
| Queen RX | $100 | $100 | Save $1249/mo |
| Elara Health and Wellness | $117 | $183 | Save $1232/mo |
| Found | $129 | $129 | Save $1220/mo |
| Peak Wellness | $129 | $249 | Save $1220/mo |
| Gimme Care | $130 | $160 | Save $1219/mo |
| Fresh Day Meds | $133 | $160 | Save $1216/mo |
| PeterMD | $135 | $165 | Save $1214/mo |
| Piper | $135 | $135 | Save $1214/mo |
| Ivologist | $145 | $159 | Save $1204/mo |
| Yucca Health | $146 | $146 | Save $1203/mo |
| CoreAge Rx | $149 | $299 | Save $1200/mo |
| Curex | $149 | $149 | Save $1200/mo |
| Nalena | $149 | $149 | Save $1200/mo |
| PlushCare | $149 | $149 | Save $1200/mo |
| Precision Telemed | $149 | $149 | Save $1200/mo |
| Tyde Wellness | $149 | $149 | Save $1200/mo |
| Vytora Health | $150 | $180 | Save $1199/mo |
| Effecty | $160 | $1600 | Save $1189/mo |
| Fella Health | $165 | $299 | Save $1184/mo |
| Ivy Rx | $175 | $175 | Save $1174/mo |
| Amble | $179 | $179 | Save $1170/mo |
| MEDVi | $179 | $299 | Save $1170/mo |
| Vaylen | $179 | $1350 | Save $1170/mo |
| Eden | $189 | $239 | Save $1160/mo |
| BetterMe Rx | $199 | $199 | Save $1150/mo |
| Hers | $199 | $199 | Save $1150/mo |
| Hims | $199 | $199 | Save $1150/mo |
| InstaRX | $199 | $199 | Save $1150/mo |
| NiceRx | $199 | $199 | Save $1150/mo |
| NovoCare Pharmacy | $199 | $399 | Save $1150/mo |
| Fitish | $219 | $219 | Save $1130/mo |
| Independent Wellness | $249 | $249 | Save $1100/mo |
| Sprout Health | $249 | $249 | Save $1100/mo |
| Cost Plus Drugs | $279 | $279 | Save $1070/mo |
| Zealthy | $286 | $286 | Save $1063/mo |
| Lemonaid Health | $348 | $348 | Save $1001/mo |
| Navio MD | $1199 | $1199 | Save $150/mo |
| Form Health | $1350 | $1350 | — |
Missouri Coverage & Regulations
Missouri permits telehealth GLP-1 prescribing. MO HealthNet Medicaid covers GLP-1s only for type 2 diabetes.
Frequently Asked Questions
Glossary references
Key terms in this article, linked to their canonical definitions.
- Wegovy · Drugs and brands
- Ozempic · Drugs and brands
- Rybelsus · Drugs and brands
- GLP-1 receptor · Mechanism
- STEP-1 · Major trials
- SELECT · Major trials
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
Related Pages
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