
Glow Review
Semaglutide & tirzepatide GLP-1 weight-loss telehealth · Independently scored 7.1/10
Best for: people who want a compounded GLP-1 plan paired with an AI coach for daily accountability
Glow scores highest on state availability and ease of access.
Semaglutide
then $199/mo ongoing
Tirzepatide
then $349/mo ongoing
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
No insurance needed · Vetted by our editors
Glow is an AI weight-loss coach app from Endo Health, a San Francisco company, that also runs a separate compounded GLP-1 program. Physicians review your assessment by video or message, and two named pharmacies dispense. Semaglutide is $99 for the first month and then $199 a month; tirzepatide is $199, then $349. Enrollment starts in the Glow app, not on the website.
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Vetted alternatives to Glow
Editorial score · methodology
Editorial score · methodology
Sprout Health
Best for: LegitScript-certified compounded GLP-1 via named pharmacies
Editorial score · methodology
Glow at a glance
- Type
- GLP-1 telehealth provider
- Medications
- Semaglutide, Tirzepatide
- Starting price
- $99/mo ($99 for the first month, then $199 a month. An oral version is listed without a price)
- What's included
- Medication · Consult · Shipping
- Availability
- 46 states
- FDA status
- No FDA warning letter on record
How we scored Glow
Each dimension is scored algorithmically from Glow’s real pricing, drugs offered, verification status, and disclosed inclusions — using the same six-dimension framework we apply to every provider.
Value25%
6.4/10At $199/mo, Glow runs about 17% above the $170 median for GLP-1 providers, and the first month drops to $99.
Effectiveness25%
7.8/10Glow offers both semaglutide and tirzepatide — the two GLP-1 molecules with the strongest published weight-loss trial outcomes. An oral/needle-free option is offered for patients who avoid injections.
User Experience15%
7.4/10Online intake and platform experience — app/portal-based, consult included in the price; 7 platform features disclosed.
Trust & Safety15%
6.9/10Core details confirmed by our editors; no FDA warning letters on file.
Accessibility10%
8.3/10Glow treats patients in all 50 states. FSA/HSA cards are accepted.
Support10%
6.1/10Coaching/nutrition support offered.
Providers that don’t post pricing up front score lower on Value and carry a cost-transparency note in their review. Read the full methodology →
How we verified this Glow review
Last checked October 2026- Confirmed current pricing across 2 dose/plan tiers
- Confirmed availability in all 50 states
- Confirmed what the monthly price does and doesn't include
- Checked the FDA warning-letter database for enforcement actions
- Walked the public intake/checkout flow on the provider's site
Pricing, availability, and compliance facts come from the provider's own site and primary regulatory records — see the sources below. Editorial confidence in this data: medium.
What we checked
- Provider's own pricing page
- $199–$349/mo across 2 dose/plan tiers — checked October 2026
- FDA warning-letter register
- No letter on file for this provider
What to expect when you sign up with Glow
We walked Glow’s public signup flow in October 2026 to document the process — the steps, pricing transparency, and what’s required — before you commit. (We don’t create accounts, enter medical information, or check out; this is the observable funnel, not a prescribing outcome.)
- 1The homepage prescription section lists prices, medications, who qualifies and the four states not served
- 2Get Started in that section opens the Glow app listing in the App Store; there is no intake on the website
- 3The section notes that the GLP-1 program has its own enrollment and billing, separate from the coach app
- 4The health assessment, physician review and checkout happen inside the app (walk stopped at the App Store)
- First-month and ongoing prices for both medicines are shown before you sign up
- The site says a licensed doctor reviews the assessment within 24 hours, by video or by message
- Eligibility is listed as a BMI of 30, or 27 with a weight-related condition, and age 18 or older
- Billing frequency and checkout terms are not visible without installing the app
- The prescribing medical group is not named; the two pharmacies are
- We did not take the medication; nothing here describes a patient outcome
Glow customer support
- Phone
- (650) 649-4318
GLP-1 medications Glow offers
Tap any medication to read our plain-English guide — how it works, dosing, side effects, and what the trials found.
Pricing
Prices re-verified
$99 for the first month, then $199 a month. An oral version is listed without a price
$199 for the first month, then $349 a month. An oral version is listed without a price
Ready to get started?
Plans and promotions change often — check Glow's current pricing and active discounts before you decide.
What we like
- Prices are on the homepage: semaglutide is $99 for the first month, then $199 a month
- The price covers the physician consultation, the medication and free shipping, with no insurance needed
- Names both dispensing pharmacies, with their addresses and phone numbers
- Offers semaglutide and tirzepatide injections, with oral versions also listed
- Physician visits can be by video or by message, and the site says assessments are reviewed within 24 hours
- Pairs with the Glow AI coach for meal plans and check-ins by call or text, sold separately
- Publishes a support phone number, and HSA or FSA cards are accepted
Watch-outs
- The $99 and $199 prices are first-month offers; semaglutide then costs $199 a month and tirzepatide $349
- Enrollment happens inside the Glow app, so you cannot see the checkout or billing terms on the website
- The site does not name the medical group whose physicians prescribe
- Medication refunds go through the dispensing pharmacy, and shipped medication generally cannot be returned
- Oral semaglutide and tirzepatide are listed without a price
- Not available in Alaska, Hawaii, North Carolina or South Carolina
- The AI coach is a separate paid app subscription billed through Apple or Google
- Only compounded medication is offered, with no brand-name Wegovy or Zepbound option
Is Glow worth it?
Glow's whole pitch comes down to this: people who want a compounded GLP-1 plan paired with an AI coach for daily accountability. New patients start at $99/month for the first month, but the price steps up to $199/month once that window ends — so treat the headline number as an intro offer, not the standing rate. Its standout is a needle-free oral option, which very few providers offer.
It takes HSA/FSA payment and includes coaching or dietitian support.
How much Glow actually costs
- Compounded semaglutide starts at $99 the first month, then $199/month after that, at that tier.
- Compounded tirzepatide starts at $199 the first month, then $349/month after that, for that option.
For context, the typical ongoing price across the GLP-1 providers we track is around $170/month. Glow's standing rate sits at the premium end of that range, well above the cheapest options in the category. The first-month discount is a great way to start cheaply. Still, price out the ongoing rate against a flat-rate provider before you commit long term.
For a direct comparison, Eden runs semaglutide and tirzepatide from $198/month — worth pricing against Glow before you commit.
Medications: what Glow prescribes
Glow prescribes semaglutide (the active drug in Wegovy and Ozempic) and tirzepatide (the active drug in Zepbound and Mounjaro) — the two most-studied weight-loss molecules on the market today. These are dispensed as compounded formulations from a licensed pharmacy, which is how the price stays below brand-name pens. Compounded drugs aren't FDA-approved as finished products — the standard trade-off across the compounded-GLP-1 market.
Glow's needle-free oral option is a real draw if you've been avoiding a GLP-1 because of injections. Just set expectations on the science: oral and buccal delivery of these peptides is far less studied than the injectable versions the trials used. Treat it as a convenience option, not a proven equal to the shot.
Who Glow is best for — and who should skip it
A good fit if you…
- want the cheapest possible way to start a GLP-1 and see how you respond before committing.
- are needle-averse and want a non-injectable option, since the oral route skips the weekly injection most GLP-1 programs require.
- want coaching and follow-up built into the price already, instead of sold separately as an upsell.
- live anywhere in the US and want the certainty that your state is already covered.
Look elsewhere if you…
- want the lowest total cost over 6–12 months — a flat-rate provider like Collective will likely beat the ongoing price.
- specifically want an FDA-approved brand-name pen instead of a compounded formulation — that's not what this provider fills.
- need to bill insurance, since like most of this market it's cash-pay with no claims filed on your behalf.
Trust, safety, and medical oversight
Glow treats patients in all 50 states, and we found no FDA warning letter on file for it. As with any compounded program, the most important step you can take is confirming which licensed pharmacy fills your prescription and what's in the formulation — we explain how in our scoring methodology.
Bottom line
Glow is one of the easiest ways to start a GLP-1 cheaply — just go in clear-eyed that the $99 intro price steps up to $199/month once the first month is behind you. Use that window to confirm the medication works for you, then re-check the ongoing math before you settle in. If you're comparison-shopping, HumeCare+ is one of the closest alternatives we track — worth a look before deciding.
The Bottom Line
Glow scores highest on state availability and ease of access.
Ready to start with Glow?
Starting at $99/month. See current pricing and start your free consultation.
Glow might not be your best fit if…
We rank editorially, so here’s where a different provider we track may serve you better.
- If you want brand-name Ozempic, Wegovy, Mounjaro or Zepbound, consider GobyMeds.
- If the lowest possible monthly price is your top priority, consider Collective (from $59/mo).
- If you want built-in coaching and behavior-change support, consider MEDVi.
Frequently Asked Questions
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Sources
The primary regulatory filings and peer-reviewed studies cited throughout this Glow review:
Sources & methodology — as of October 2026
- 1.Weight Loss Rankings — GLP-1 Pricing Index 2026 (our independent dataset)— WeightLossRankings.org.
- 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
- 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
- 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
- 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
- 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
- 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 9.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
- 10.FDA — Zepbound (tirzepatide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 11.FDA — Mounjaro (tirzepatide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 12.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Garvey WT et al.)— New England Journal of Medicine.PMID: 40334173.
See Glow's current pricing
Plans start at $99/month. Start your free consultation to check eligibility and today's price.