Ro vs RxSpan MD
In our scoring, RxSpan MD edges ahead overall (8.1 vs 7.7 out of 10).
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Key differences
- Price
- Ro $349/mo plus a separate membership; RxSpan MD $1,299/mo no prepay listed (brand-name Wegovy / Ozempic · not like-for-like, so neither is marked cheaper)
- Coverage
- RxSpan MD 50 states (Ro doesn't publish a state list)
- Included
- Ro: clinician visits, labs, coaching (not included: medication); RxSpan MD: medication, clinician visits, shipping, coaching

Ro
Affiliate partnerBest for FDA-approved brand GLP-1s, including the Wegovy pill and Foundayo, with insurance help
Brand-name Wegovy / Ozempic
$349
+ separate membership · $199 first month
Our score 7.7/10

RxSpan MD
Affiliate partnerBest for physician-led, pharmacy-transparent compounded GLP-1 with brand-name options
semaglutide
$249
Our score 8.1/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Ro
RxSpan MD
Price
Brand Wegovy / Ozempic / month
$349/mo
+ separate membership · $199 first month
$1,299/mo
Brand Wegovy / Ozempic / year (modeled)
$4,188
excludes the membership
$15,588
Brand Zepbound / Mounjaro / month
$299/mo
+ separate membership
$1,069/mo
Brand Zepbound / Mounjaro / year (modeled)
$3,588
excludes the membership
$12,828
Semaglutide / month
Not listed
$249/mo
Tirzepatide / month
Not listed
$329/mo
Oral semaglutide / month
Not listed
$249/mo
Oral tirzepatide / month
Not listed
$349/mo
Brand Wegovy pill / Rybelsus / month
$149/mo
+ separate membership · other plan terms available
Not listed
Brand Foundayo / month
$149/mo
+ separate membership
Not listed
Separate membership required
Yes — not in the listed price
Not stated
Coverage
State availability
List not published
50 states
Oral option listed
Yes
Yes
Brand-name access listed
Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo
Wegovy / Ozempic, Zepbound / Mounjaro
Included in the price
Clinician visits, labs, coaching
Not included: medication
Medication, clinician visits, shipping, coaching
Terms & safety
Price shown
Before intake
Before intake
Cancel anytime
Yes
Yes
Minimum commitment
None required; optional 3-, 6- and 12-month prepaid membership plans ('You'll pay upfront for your entire multi-month membership or medication plan').
None
Refunds
'Your previously incurred monthly fees are nonrefundable.' Prescription products: 'all sales are final.' The $39 first month 'will be refunded if you're not eligible for GLP-1s.'
Not disclosed
Early-cancellation fee
Not disclosed
None
FDA warning letters
None on record
None on record
Provider facts checked
October 2026
August 2026
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.

Choose Ro if…
- Lists brand-name Wegovy pill / Rybelsus and brand-name Foundayo, which RxSpan MD doesn't price
- Broad FDA-approved menu: Wegovy pill and pen, Zepbound, Foundayo and Ozempic
- Cash prices match LillyDirect, NovoCare and TrumpRx, with every dose price published
What to weigh up
- Listed brand-name Wegovy / Ozempic price excludes a required membership
- No published state list; confirm yours at signup

Choose RxSpan MD if…
- Lists compounded semaglutide, compounded tirzepatide and oral compounded semaglutide, which Ro doesn't price
- Publishes its full state list (50 states)
- Price includes medication; Ro's doesn't
What to weigh up
- Compounded pricing ($249 semaglutide / $329 tirzepatide) sits mid-to-high versus the cheapest telehealth options
- Brand-name GLP-1 is priced steeply (Wegovy $1,349, Ozempic $1,299, Zepbound $1,069)
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Ro
7.7/10
RxSpan MD
8.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
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Found
Compounded GLP-1 with medication included from $169/mo cash, plus insurance help for brand GLP-1s
Read full review →From $169/mo
Get started →GobyMeds
No-membership, no-auto-renew compounded GLP-1 orders, from about $99/mo on a 3-month bundle
Read full review →From $169/mo
Get started →Ivim Health
Compounded GLP-1 with weekly provider check-ins and health coaches, under a required monthly membership
Read full review →From $65/mo + membership
Get started →Ro vs RxSpan MD: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.