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Ro vs RxSpan MD

In our scoring, RxSpan MD edges ahead overall (8.1 vs 7.7 out of 10).

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed

Key differences

Price
Ro $349/mo plus a separate membership; RxSpan MD $1,299/mo no prepay listed (brand-name Wegovy / Ozempic · not like-for-like, so neither is marked cheaper)
Coverage
RxSpan MD 50 states (Ro doesn't publish a state list)
Included
Ro: clinician visits, labs, coaching (not included: medication); RxSpan MD: medication, clinician visits, shipping, coaching

How we compare providers

Ro logo

Ro

Affiliate partner

Best for FDA-approved brand GLP-1s, including the Wegovy pill and Foundayo, with insurance help

Brand-name Wegovy / Ozempic

$349/mo

+ separate membership · $199 first month

Our score 7.7/10

RxSpan MD logo

RxSpan MD

Affiliate partner

Best for physician-led, pharmacy-transparent compounded GLP-1 with brand-name options

semaglutide

$249/mo

Our score 8.1/10

We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.

Costs & coverage

Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.

Ro

RxSpan MD

Price

Brand Wegovy / Ozempic / month

$349/mo

+ separate membership · $199 first month

$1,299/mo

Brand Wegovy / Ozempic / year (modeled)

$4,188

excludes the membership

$15,588

Brand Zepbound / Mounjaro / month

$299/mo

+ separate membership

$1,069/mo

Brand Zepbound / Mounjaro / year (modeled)

$3,588

excludes the membership

$12,828

Semaglutide / month

Not listed

$249/mo

Tirzepatide / month

Not listed

$329/mo

Oral semaglutide / month

Not listed

$249/mo

Oral tirzepatide / month

Not listed

$349/mo

Brand Wegovy pill / Rybelsus / month

$149/mo

+ separate membership · other plan terms available

Not listed

Brand Foundayo / month

$149/mo

+ separate membership

Not listed

Separate membership required

Yes — not in the listed price

Not stated

Coverage

State availability

List not published

50 states

Oral option listed

Yes

Yes

Brand-name access listed

Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo

Wegovy / Ozempic, Zepbound / Mounjaro

Included in the price

Clinician visits, labs, coaching

Not included: medication

Medication, clinician visits, shipping, coaching

Terms & safety

Price shown

Before intake

Before intake

Cancel anytime

Yes

Yes

Minimum commitment

None required; optional 3-, 6- and 12-month prepaid membership plans ('You'll pay upfront for your entire multi-month membership or medication plan').

None

Refunds

'Your previously incurred monthly fees are nonrefundable.' Prescription products: 'all sales are final.' The $39 first month 'will be refunded if you're not eligible for GLP-1s.'

Not disclosed

Early-cancellation fee

Not disclosed

None

FDA warning letters

None on record

None on record

Provider facts checked

October 2026

August 2026

Every dose and plan: Ro · RxSpan MD

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Which fits your priorities?

Only the points where these two differ, from the table above and each provider’s record.

Ro logo

Choose Ro if…

  • Lists brand-name Wegovy pill / Rybelsus and brand-name Foundayo, which RxSpan MD doesn't price
  • Broad FDA-approved menu: Wegovy pill and pen, Zepbound, Foundayo and Ozempic
  • Cash prices match LillyDirect, NovoCare and TrumpRx, with every dose price published

What to weigh up

  • Listed brand-name Wegovy / Ozempic price excludes a required membership
  • No published state list; confirm yours at signup
RxSpan MD logo

Choose RxSpan MD if…

  • Lists compounded semaglutide, compounded tirzepatide and oral compounded semaglutide, which Ro doesn't price
  • Publishes its full state list (50 states)
  • Price includes medication; Ro's doesn't

What to weigh up

  • Compounded pricing ($249 semaglutide / $329 tirzepatide) sits mid-to-high versus the cheapest telehealth options
  • Brand-name GLP-1 is priced steeply (Wegovy $1,349, Ozempic $1,299, Zepbound $1,069)

Explore the scoring factors

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Ro

7.7/10

Overall

RxSpan MD

8.1/10

Value25%

6.0A
vs
B
7.0

Effectiveness25%

9.0A
vs
B
8.5

User Experience15%

8.0A
vs
B
7.5

Trust & Safety15%

7.8A
vs
B
9.3

Accessibility10%

7.5A
vs
B
8.5

Support10%

8.5A
vs
B
8.9

Ready to start? Vetted GLP-1 providers

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8.3

Found

Compounded GLP-1 with medication included from $169/mo cash, plus insurance help for brand GLP-1s

Read full review →

From $169/mo

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7.9

GobyMeds

No-membership, no-auto-renew compounded GLP-1 orders, from about $99/mo on a 3-month bundle

Read full review →

From $169/mo

Get started →
7.7

Ivim Health

Compounded GLP-1 with weekly provider check-ins and health coaches, under a required monthly membership

Read full review →

From $65/mo + membership

Get started →

Ro vs RxSpan MD: FAQ

RxSpan MD scores higher overall at 8.1/10 versus 7.7/10, and is particularly strong for physician-led, pharmacy-transparent compounded GLP-1 with brand-name options. That said, Ro is a better fit if you want FDA-approved brand GLP-1s, including the Wegovy pill and Foundayo, with insurance help.
Both Ro and RxSpan MD are affiliate partners, meaning we may earn a commission if you sign up through our links. Our scores are assigned editorially using the same six-dimension framework for every provider — partnership never changes a score. We disclose every commercial relationship.
Ro: $349, medication only (a separate membership is required), about $4,188 a year; first month $199. RxSpan MD: $1,299, about $15,588 a year. Not like-for-like: one figure excludes a required membership.
Ro doesn't publish a state list. RxSpan MD publishes 50 states. Where a list isn't published, confirm your state during sign-up before paying.
Ro: cancel anytime — yes; minimum commitment — None required; optional 3-, 6- and 12-month prepaid membership plans ('You'll pay upfront for your entire multi-month membership or medication plan').; early-cancellation fee — not disclosed. RxSpan MD: cancel anytime — yes; minimum commitment — None; early-cancellation fee — none. Check the provider's own terms before you buy.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring Ro and RxSpan MD head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.