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Midi Health vs RxSpan MD

In our scoring, RxSpan MD edges ahead overall (8.1 vs 7.0 out of 10), and Midi Health costs less for compounded semaglutide (about $831 a year less; one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost).

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed

Key differences

Price
Midi Health $165.90/mo vs RxSpan MD $249/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $831 a year less with Midi Health · one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
Coverage
Both serve the same 50 states
Included
Midi Health: not stated; RxSpan MD: medication, clinician visits, shipping, coaching

How we compare providers

Midi Health logo

Midi Health

Affiliate partner

Best for menopause-focused care with GLP-1 as a metabolic adjunct

semaglutide

$165.90/mo

billed every 4 weeks

Our score 7.0/10

RxSpan MD logo

RxSpan MD

Affiliate partner

Best for physician-led, pharmacy-transparent compounded GLP-1 with brand-name options

semaglutide

$249/mo

Our score 8.1/10

We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.

Costs & coverage

Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.

Midi Health

RxSpan MD

Price

Semaglutide / month

Better on this row: $165.90/mo

billed every 4 weeks

$249/mo

Semaglutide / year (modeled)

Better on this row: $2,157

13 charges

$2,988

Tirzepatide / month

Better on this row: $210/mo

billed every 4 weeks

$329/mo

Tirzepatide / year (modeled)

Better on this row: $2,730

13 charges

$3,948

Oral semaglutide / month

Better on this row: $164/mo

billed every 4 weeks

$249/mo

Oral semaglutide / year (modeled)

Better on this row: $2,132

13 charges

$2,988

Oral tirzepatide / month

Better on this row: $209/mo

billed every 4 weeks

$349/mo

Oral tirzepatide / year (modeled)

Better on this row: $2,717

13 charges

$4,188

Brand Wegovy / Ozempic / month

Not listed

$1,299/mo

Brand Zepbound / Mounjaro / month

Not listed

$1,069/mo

Coverage

State availability

50 states

50 states

Oral option listed

Yes

Yes

Brand-name access listed

Not listed

Wegovy / Ozempic, Zepbound / Mounjaro

Included in the price

Not disclosed

Medication, clinician visits, shipping, coaching

Terms & safety

Price shown

Plan quoted after intake; a price is published

Before intake

Video visit

Required

Not disclosed

Cancel anytime

Not disclosed

Yes

Minimum commitment

Not disclosed

None

Early-cancellation fee

Not disclosed

None

FDA warning letters

None on record

None on record

Provider facts checked

August 2026

August 2026

Every dose and plan: Midi Health · RxSpan MD

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Which fits your priorities?

Only the points where these two differ, from the table above and each provider’s record.

Midi Health logo

Choose Midi Health if…

  • About $831 a year less than RxSpan MD for compounded semaglutide at standing prices (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
  • Accepts commercial insurance — a differentiator vs cash-pay-only GLP-1 telehealth
  • Menopause + metabolic-health focus suits women where GLP-1 efficacy and weight regulation overlap most

What to weigh up

  • Does not accept Medicare, Medicaid, or Medi-Cal
  • GLP-1 is prescribed at clinician discretion within a menopause plan, not guaranteed at intake
RxSpan MD logo

Choose RxSpan MD if…

  • Lists brand-name Wegovy / Ozempic and brand-name Zepbound / Mounjaro, which Midi Health doesn't price
  • Physician-led — founded by Dr. John Diaz, a board-certified plastic surgeon with 20+ years' experience
  • Names its 503A pharmacy partners (Belmar, Strive, Epiq Scripts, Casa Pharma) and medical group

What to weigh up

  • About $831 a year more than Midi Health for compounded semaglutide (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
  • Compounded pricing ($249 semaglutide / $329 tirzepatide) sits mid-to-high versus the cheapest telehealth options

Explore the scoring factors

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Midi Health

7.0/10

Overall

RxSpan MD

8.1/10

Value25%

7.0A
vs
B
7.0

Effectiveness25%

7.0A
vs
B
8.5

User Experience15%

7.0A
vs
B
7.5

Trust & Safety15%

7.3A
vs
B
9.3

Accessibility10%

6.5A
vs
B
8.5

Support10%

7.0A
vs
B
8.9

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7.9

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No-membership, no-auto-renew compounded GLP-1 orders, from about $99/mo on a 3-month bundle

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Midi Health vs RxSpan MD: FAQ

For compounded semaglutide, Midi Health costs less: about $831 less a year at the standing price, with no prepay or separate membership listed (not a first-month promo); one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost. See Costs & coverage above for each medication side by side.
RxSpan MD scores higher overall at 8.1/10 versus 7.0/10, and is particularly strong for physician-led, pharmacy-transparent compounded GLP-1 with brand-name options. That said, Midi Health is a better fit if you want menopause-focused care with GLP-1 as a metabolic adjunct.
Both Midi Health and RxSpan MD are affiliate partners, meaning we may earn a commission if you sign up through our links. Our scores are assigned editorially using the same six-dimension framework for every provider — partnership never changes a score. We disclose every commercial relationship.
Midi Health: $165.90 (billed every 4 weeks, 13 charges a year), about $2,157 a year. RxSpan MD: $249, about $2,988 a year. Midi Health costs about $831 less a year at these prices.
Both publish the same list (50 states), so where you live won't decide between them.
Midi Health doesn't state its cancellation terms. RxSpan MD: cancel anytime — yes; minimum commitment — None; early-cancellation fee — none. Check the provider's own terms before you buy.

Key terms, explained

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Continue exploring Midi Health and RxSpan MD head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.