Midi Health vs RxSpan MD
In our scoring, RxSpan MD edges ahead overall (8.1 vs 7.0 out of 10), and Midi Health costs less for compounded semaglutide (about $831 a year less; one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost).
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Key differences
- Price
- Midi Health $165.90/mo vs RxSpan MD $249/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $831 a year less with Midi Health · one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- Coverage
- Both serve the same 50 states
- Included
- Midi Health: not stated; RxSpan MD: medication, clinician visits, shipping, coaching
Midi Health
Affiliate partnerBest for menopause-focused care with GLP-1 as a metabolic adjunct
semaglutide
$165.90
billed every 4 weeks
Our score 7.0/10

RxSpan MD
Affiliate partnerBest for physician-led, pharmacy-transparent compounded GLP-1 with brand-name options
semaglutide
$249
Our score 8.1/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Midi Health
RxSpan MD
Price
Semaglutide / month
Better on this row: $165.90/mo
billed every 4 weeks
$249/mo
Semaglutide / year (modeled)
Better on this row: $2,157
13 charges
$2,988
Tirzepatide / month
Better on this row: $210/mo
billed every 4 weeks
$329/mo
Tirzepatide / year (modeled)
Better on this row: $2,730
13 charges
$3,948
Oral semaglutide / month
Better on this row: $164/mo
billed every 4 weeks
$249/mo
Oral semaglutide / year (modeled)
Better on this row: $2,132
13 charges
$2,988
Oral tirzepatide / month
Better on this row: $209/mo
billed every 4 weeks
$349/mo
Oral tirzepatide / year (modeled)
Better on this row: $2,717
13 charges
$4,188
Brand Wegovy / Ozempic / month
Not listed
$1,299/mo
Brand Zepbound / Mounjaro / month
Not listed
$1,069/mo
Coverage
State availability
50 states
50 states
Oral option listed
Yes
Yes
Brand-name access listed
Not listed
Wegovy / Ozempic, Zepbound / Mounjaro
Included in the price
Not disclosed
Medication, clinician visits, shipping, coaching
Terms & safety
Price shown
Plan quoted after intake; a price is published
Before intake
Video visit
Required
Not disclosed
Cancel anytime
Not disclosed
Yes
Minimum commitment
Not disclosed
None
Early-cancellation fee
Not disclosed
None
FDA warning letters
None on record
None on record
Provider facts checked
August 2026
August 2026
Every dose and plan: Midi Health · RxSpan MD
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Midi Health if…
- About $831 a year less than RxSpan MD for compounded semaglutide at standing prices (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- Accepts commercial insurance — a differentiator vs cash-pay-only GLP-1 telehealth
- Menopause + metabolic-health focus suits women where GLP-1 efficacy and weight regulation overlap most
What to weigh up
- Does not accept Medicare, Medicaid, or Medi-Cal
- GLP-1 is prescribed at clinician discretion within a menopause plan, not guaranteed at intake

Choose RxSpan MD if…
- Lists brand-name Wegovy / Ozempic and brand-name Zepbound / Mounjaro, which Midi Health doesn't price
- Physician-led — founded by Dr. John Diaz, a board-certified plastic surgeon with 20+ years' experience
- Names its 503A pharmacy partners (Belmar, Strive, Epiq Scripts, Casa Pharma) and medical group
What to weigh up
- About $831 a year more than Midi Health for compounded semaglutide (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- Compounded pricing ($249 semaglutide / $329 tirzepatide) sits mid-to-high versus the cheapest telehealth options
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Midi Health
7.0/10
RxSpan MD
8.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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Get started →Midi Health vs RxSpan MD: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.