MadeMed vs RxSpan MD
In our scoring, RxSpan MD edges ahead overall (8.1 vs 7.4 out of 10), and MadeMed costs less for compounded semaglutide (about $120 a year less).
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Key differences
- Price
- MadeMed $239/mo vs RxSpan MD $249/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $120 a year less with MadeMed)
- Coverage
- RxSpan MD 50 states (MadeMed doesn't publish a state list)
- Included
- MadeMed: not stated; RxSpan MD: medication, clinician visits, shipping, coaching
MadeMed
Affiliate partnerBest for compounded GLP-1 in both injection and oral forms
semaglutide
$239
Our score 7.4/10
RxSpan MD
Affiliate partnerBest for physician-led, pharmacy-transparent compounded GLP-1 with brand-name options
semaglutide
$249
Our score 8.1/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
MadeMed
RxSpan MD
Price
Semaglutide / month
Better on this row: $239/mo
$249/mo
Semaglutide / year (modeled)
Better on this row: $2,868
$2,988
Tirzepatide / month
$399/mo
Better on this row: $329/mo
Tirzepatide / year (modeled)
$4,788
Better on this row: $3,948
Oral semaglutide / month
Better on this row: $219/mo
$249/mo
Oral semaglutide / year (modeled)
Better on this row: $2,628
$2,988
Oral tirzepatide / month
Better on this row: $299/mo
$349/mo
Oral tirzepatide / year (modeled)
Better on this row: $3,588
$4,188
Brand Wegovy / Ozempic / month
Not listed
$1,299/mo
Brand Zepbound / Mounjaro / month
Not listed
$1,069/mo
Coverage
State availability
List not published
50 states
Oral option listed
Yes
Yes
Brand-name access listed
Not listed
Wegovy / Ozempic, Zepbound / Mounjaro
Included in the price
Not disclosed
Medication, clinician visits, shipping, coaching
Terms & safety
Price shown
Before intake
Before intake
Lab work
Not required
Not disclosed
Video visit
Not required
Not disclosed
Cancel anytime
Not disclosed
Yes
Minimum commitment
Not disclosed
None
Early-cancellation fee
Not disclosed
None
FDA warning letters
None on record
None on record
Provider facts checked
August 2026
August 2026
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose MadeMed if…
- About $120 a year less than RxSpan MD for compounded semaglutide at standing prices
- LegitScript certification badge on the homepage
- Customer phone support published (1-800-582-1428) — uncommon vs chat-only competitors
What to weigh up
- No published state list; confirm yours at signup
- Pricing not shown publicly — gated behind product pages or checkout
Choose RxSpan MD if…
- Lists brand-name Wegovy / Ozempic and brand-name Zepbound / Mounjaro, which MadeMed doesn't price
- Publishes its full state list (50 states)
- Physician-led — founded by Dr. John Diaz, a board-certified plastic surgeon with 20+ years' experience
What to weigh up
- About $120 a year more than MadeMed for compounded semaglutide
- Compounded pricing ($249 semaglutide / $329 tirzepatide) sits mid-to-high versus the cheapest telehealth options
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
MadeMed
7.4/10
RxSpan MD
8.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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From $219/mo
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Compounded GLP-1 with medication included from $169/mo cash, plus insurance help for brand GLP-1s
Read full review →From $169/mo
Get started →GobyMeds
No-membership, no-auto-renew compounded GLP-1 orders, from about $99/mo on a 3-month bundle
Read full review →From $169/mo
Get started →MadeMed vs RxSpan MD: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.