altRX vs RxSpan MD
In our scoring, RxSpan MD edges ahead overall (8.1 vs 7.4 out of 10), and altRX costs less for compounded semaglutide (about $1,920 a year less).
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Key differences
- Price
- altRX $89/mo vs RxSpan MD $249/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $1,920 a year less with altRX)
- Coverage
- RxSpan MD 50 states (altRX doesn't publish a state list)
- Included
- altRX: medication, clinician visits, shipping; RxSpan MD: medication, clinician visits, shipping, coaching
- Safety
- FDA warning letters on record: altRX 1, RxSpan MD none
altRX
Affiliate partnerBest for low-cost compounded GLP-1s with brand-name Zepbound, Wegovy and Ozempic as options
semaglutide
$89
Our score 7.4/10
RxSpan MD
Affiliate partnerBest for physician-led, pharmacy-transparent compounded GLP-1 with brand-name options
semaglutide
$249
Our score 8.1/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
altRX
RxSpan MD
Price
Semaglutide / month
Better on this row: $89/mo
$249/mo
Semaglutide / year (modeled)
Better on this row: $1,068
$2,988
Tirzepatide / month
Better on this row: $149/mo
$329/mo
Tirzepatide / year (modeled)
Better on this row: $1,788
$3,948
Brand Wegovy / Ozempic / month
Better on this row: $1,149/mo
$1,299/mo
Brand Wegovy / Ozempic / year (modeled)
Better on this row: $13,788
$15,588
Brand Zepbound / Mounjaro / month
$1,249/mo
Better on this row: $1,069/mo
Brand Zepbound / Mounjaro / year (modeled)
$14,988
Better on this row: $12,828
Oral semaglutide / month
Not listed
$249/mo
Oral tirzepatide / month
Not listed
$349/mo
Coverage
State availability
List not published
50 states
Oral option listed
Not listed
Yes
Brand-name access listed
Wegovy / Ozempic, Zepbound / Mounjaro
Wegovy / Ozempic, Zepbound / Mounjaro
Included in the price
Medication, clinician visits, shipping
Medication, clinician visits, shipping, coaching
Terms & safety
Price shown
Before intake
Before intake
Cancel anytime
Yes
Yes
Minimum commitment
Single-month and multi-month plans; multi-month plans are a single, non-refundable purchase for the full term
None
Refunds
Refund policy (Aug 25, 2026): 'ALL PAYMENTS FOR THE SUBSCRIPTION SERVICES ARE FINAL AND NON-REFUNDABLE AT THE TIME OF PURCHASE.' A medical disqualification refunds the unused portion minus consultations, provider review and other services already rendered.
Not disclosed
Early-cancellation fee
Not disclosed
None
FDA warning letters
1 warning letter
Better on this row: None on record
Provider facts checked
October 2026
August 2026
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose altRX if…
- About $1,920 a year less than RxSpan MD for compounded semaglutide at standing prices
- Brand-name Zepbound, Wegovy and Ozempic available alongside compounded options
- Names its four partner compounding pharmacies, with addresses and phone numbers
What to weigh up
- 1 FDA warning letter on record
- No published state list; confirm yours at signup
Choose RxSpan MD if…
- Lists oral compounded semaglutide and oral compounded tirzepatide, which altRX doesn't price
- Publishes its full state list (50 states)
- No FDA warning letters on record (altRX has 1)
What to weigh up
- About $1,920 a year more than altRX for compounded semaglutide
- Compounded pricing ($249 semaglutide / $329 tirzepatide) sits mid-to-high versus the cheapest telehealth options
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
altRX
7.4/10
RxSpan MD
8.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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altRX vs RxSpan MD: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.