RxSpan MD vs Wellorithm
In our scoring, RxSpan MD edges ahead overall (8.1 vs 6.2 out of 10).
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Key differences
- Price
- RxSpan MD $249/mo for compounded semaglutide; Wellorithm $247/mo for compounded semaglutide (pill or injection) (different medications, so not compared on price)
- Coverage
- RxSpan MD 50 states; Wellorithm 49 states (only RxSpan MD: Louisiana)
- Included
- RxSpan MD: medication, clinician visits, shipping, coaching; Wellorithm: not stated

RxSpan MD
Affiliate partnerBest for physician-led, pharmacy-transparent compounded GLP-1 with brand-name options
semaglutide
$249
Our score 8.1/10

Wellorithm
Affiliate partnerBest for compounded GLP-1 access with oral tablet options across 49 states
semaglutide (pill or injection)
$247
$147 first month
Our score 6.2/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
RxSpan MD
Wellorithm
Price
Semaglutide / month
$249/mo
Not listed
Tirzepatide / month
$329/mo
Not listed
Semaglutide (pill or injection) / month
Not listed
$247/mo
$147 first month
Tirzepatide (pill or injection) / month
Not listed
$347/mo
$247 first month
Oral semaglutide / month
$249/mo
Not listed
Oral tirzepatide / month
$349/mo
Not listed
Brand Wegovy / Ozempic / month
$1,299/mo
Not listed
Brand Zepbound / Mounjaro / month
$1,069/mo
Not listed
Coverage
State availability
50 states
49 states
Oral option listed
Yes
Not listed
Brand-name access listed
Wegovy / Ozempic, Zepbound / Mounjaro
Not listed
Included in the price
Medication, clinician visits, shipping, coaching
Not disclosed
Terms & safety
Price shown
Before intake
Plan quoted after intake; a price is published
Cancel anytime
Yes
Not disclosed
Minimum commitment
None
Not disclosed
Early-cancellation fee
None
Not disclosed
FDA warning letters
None on record
None on record
Provider facts checked
August 2026
August 2026
Show where they differ by stateHide state lists
Only RxSpan MD (1 state)
- Louisiana
Every dose and plan: RxSpan MD · Wellorithm
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.

Choose RxSpan MD if…
- Lists compounded semaglutide, compounded tirzepatide and oral compounded semaglutide, which Wellorithm doesn't price
- Serves Louisiana, where Wellorithm doesn't
- Physician-led — founded by Dr. John Diaz, a board-certified plastic surgeon with 20+ years' experience
What to weigh up
- Compounded pricing ($249 semaglutide / $329 tirzepatide) sits mid-to-high versus the cheapest telehealth options
- Brand-name GLP-1 is priced steeply (Wegovy $1,349, Ozempic $1,299, Zepbound $1,069)

Choose Wellorithm if…
- Lists compounded semaglutide (pill or injection) and compounded tirzepatide (pill or injection), which RxSpan MD doesn't price
- Four compounded GLP-1 formats: semaglutide and tirzepatide as injectables or oral dissolving tablets
- Available in 49 states — broader than most compounded GLP-1 providers
What to weigh up
- Not available in Louisiana
- Pricing not shown until you complete the intake quiz
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
RxSpan MD
8.1/10
Wellorithm
6.2/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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Found
Compounded GLP-1 with medication included from $169/mo cash, plus insurance help for brand GLP-1s
Read full review →From $169/mo
Get started →GobyMeds
No-membership, no-auto-renew compounded GLP-1 orders, from about $99/mo on a 3-month bundle
Read full review →From $169/mo
Get started →Ivim Health
Compounded GLP-1 with weekly provider check-ins and health coaches, under a required monthly membership
Read full review →From $65/mo + membership
Get started →RxSpan MD vs Wellorithm: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.