MangoRx vs RxSpan MD
In our scoring, RxSpan MD edges ahead overall (8.1 vs 5.5 out of 10), and RxSpan MD costs less for oral compounded semaglutide (about $600 a year less).
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Key differences
- Price
- RxSpan MD $249/mo vs MangoRx $299/mo for oral compounded semaglutide (standing prices, no prepay or separate membership listed · about $600 a year less with RxSpan MD)
- Coverage
- RxSpan MD 50 states (MangoRx doesn't publish a state list)
- Included
- MangoRx: medication, clinician visits; RxSpan MD: medication, clinician visits, shipping, coaching
MangoRx
Affiliate partnerBest for men's-health shoppers who want oral compounded semaglutide at one flat price across doses
Oral compounded semaglutide
$299
$269.10 first month
Our score 5.5/10
RxSpan MD
Affiliate partnerBest for physician-led, pharmacy-transparent compounded GLP-1 with brand-name options
semaglutide
$249
Our score 8.1/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
MangoRx
RxSpan MD
Price
Oral semaglutide / month
$299/mo
$269.10 first month
Better on this row: $249/mo
Oral semaglutide / year (modeled)
$3,588
Better on this row: $2,988
Semaglutide / month
Not listed
$249/mo
Tirzepatide / month
Not listed
$329/mo
Oral tirzepatide / month
Not listed
$349/mo
Brand Wegovy / Ozempic / month
Not listed
$1,299/mo
Brand Zepbound / Mounjaro / month
Not listed
$1,069/mo
Coverage
State availability
List not published
50 states
Oral option listed
Yes
Yes
Brand-name access listed
Not listed
Wegovy / Ozempic, Zepbound / Mounjaro
Included in the price
Medication, clinician visits
Medication, clinician visits, shipping, coaching
Terms & safety
Price shown
Plan quoted after intake; a price is published
Before intake
Cancel anytime
Not disclosed
Yes
Minimum commitment
None
None
Refunds
Full refund if declined, else all sales final
Not disclosed
Early-cancellation fee
Not disclosed
None
FDA warning letters
None on record
None on record
Provider facts checked
August 2026
August 2026
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose MangoRx if…
- Men's-health telehealth that bundles GLP-1, TRT, ED, and hair care under one provider
What to weigh up
- About $600 a year more than RxSpan MD for oral compounded semaglutide
- No published state list; confirm yours at signup
Choose RxSpan MD if…
- About $600 a year less than MangoRx for oral compounded semaglutide at standing prices
- Lists compounded semaglutide, compounded tirzepatide and oral compounded tirzepatide, which MangoRx doesn't price
- Publishes its full state list (50 states)
What to weigh up
- Compounded pricing ($249 semaglutide / $329 tirzepatide) sits mid-to-high versus the cheapest telehealth options
- Brand-name GLP-1 is priced steeply (Wegovy $1,349, Ozempic $1,299, Zepbound $1,069)
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
MangoRx
5.5/10
RxSpan MD
8.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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Compounded GLP-1 with medication included from $169/mo cash, plus insurance help for brand GLP-1s
Read full review →From $169/mo
Get started →GobyMeds
No-membership, no-auto-renew compounded GLP-1 orders, from about $99/mo on a 3-month bundle
Read full review →From $169/mo
Get started →MangoRx vs RxSpan MD: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.