Collective vs RxSpan MD
In our scoring, Collective edges ahead overall (8.3 vs 8.1 out of 10).
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Key differences
- Price
- Collective $59/mo plus a separate membership; RxSpan MD $249/mo no prepay listed (compounded semaglutide · not like-for-like, so neither is marked cheaper)
- Coverage
- Collective 44 states; RxSpan MD 50 states (only RxSpan MD: Alabama, California, Louisiana and 3 more)
- Included
- Collective: medication, clinician visits, shipping; RxSpan MD: medication, clinician visits, shipping, coaching

Collective
Affiliate partnerBest for the lowest flat medication price if you can absorb an annual membership fee
semaglutide
$59
+ separate membership
Our score 8.3/10

RxSpan MD
Affiliate partnerBest for physician-led, pharmacy-transparent compounded GLP-1 with brand-name options
semaglutide
$249
Our score 8.1/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Collective
RxSpan MD
Price
Semaglutide / month
$59/mo
+ separate membership
$249/mo
Semaglutide / year (modeled)
$708
excludes the membership
$2,988
Tirzepatide / month
$69/mo
+ separate membership
$329/mo
Tirzepatide / year (modeled)
$828
excludes the membership
$3,948
Oral semaglutide / month
Not listed
$249/mo
Oral tirzepatide / month
Not listed
$349/mo
Brand Wegovy / Ozempic / month
Not listed
$1,299/mo
Brand Zepbound / Mounjaro / month
Not listed
$1,069/mo
Separate membership required
Yes, not in the listed price
Not stated
Coverage
State availability
44 states
50 states
Oral option listed
Not listed
Yes
Brand-name access listed
Not listed
Wegovy / Ozempic, Zepbound / Mounjaro
Included in the price
Medication, clinician visits, shipping
Medication, clinician visits, shipping, coaching
Terms & safety
Price shown
Before intake
Before intake
Cancel anytime
Yes
Yes
Minimum commitment
Medication is month-to-month; the membership is billed annually
None
Refunds
'All membership fees are non-refundable, and partial-period refunds are not provided.'
Not disclosed
Early-cancellation fee
None
None
FDA warning letters
None on record
None on record
Provider facts checked
October 2026
August 2026
Show where they differ by stateHide state lists
Only RxSpan MD (6 states)
- Alabama
- California
- Louisiana
- Massachusetts
- Mississippi
- Washington
Every dose and plan: Collective · RxSpan MD
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.

Choose Collective if…
- Flat pricing at every dose, so titrating up does not raise the bill
- Unlimited doctor messaging, quarterly check-ins and registered-dietitian access are included rather than upsold
- An optional twice-a-week dosing schedule and anti-nausea prescriptions when needed, aimed at the side effects that make people quit
What to weigh up
- Listed compounded semaglutide price excludes a required membership
- Not available in 6 states that RxSpan MD serves

Choose RxSpan MD if…
- Lists oral compounded semaglutide, oral compounded tirzepatide and brand-name Wegovy / Ozempic, which Collective doesn't price
- Serves 6 states that Collective doesn't
- Physician-led: founded by Dr. John Diaz, a board-certified plastic surgeon with 20+ years' experience
What to weigh up
- Compounded pricing ($249 semaglutide / $329 tirzepatide) sits mid-to-high versus the cheapest telehealth options
- Brand-name GLP-1 is priced steeply (Wegovy $1,349, Ozempic $1,299, Zepbound $1,069)
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Collective
8.3/10
RxSpan MD
8.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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Gala
Compounded semaglutide or tirzepatide at one all-doses price on a yearly plan, with free shipping
Read full review →From $129/mo (starting dose)
Get started →Found
Medication-included compounded GLP-1 from $169/mo on a 12-month prepaid plan, plus brand insurance help
Read full review →From $169/mo (12-month plan rate)
Get started →Oak
Compounded semaglutide and tirzepatide at a low starting price, with a full price list before you sign up
Read full review →From $200/mo (starting dose)
Get started →Collective vs RxSpan MD: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking, or alternatives to Collective and RxSpan MD.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.