Belle Health vs RxSpan MD
In our scoring, RxSpan MD edges ahead overall (8.1 vs 7.6 out of 10), and Belle Health costs less for compounded semaglutide (about $600 a year less).
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Key differences
- Price
- Belle Health $199/mo vs RxSpan MD $249/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $600 a year less with Belle Health)
- Coverage
- Both serve the same 50 states
- Included
- Belle Health: medication, clinician visits, shipping, coaching; RxSpan MD: medication, clinician visits, shipping, coaching
- Safety
- FDA warning letters on record: Belle Health 1, RxSpan MD none
Belle Health
Affiliate partnerBest for flat-rate compounded GLP-1 with weekly dietitian check-ins and long-plan discounts
semaglutide
$199
Our score 7.6/10

RxSpan MD
Affiliate partnerBest for physician-led, pharmacy-transparent compounded GLP-1 with brand-name options
semaglutide
$249
Our score 8.1/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Belle Health
RxSpan MD
Price
Semaglutide / month
Better on this row: $199/mo
$249/mo
Semaglutide / year (modeled)
Better on this row: $2,388
$2,988
Tirzepatide / month
Better on this row: $249/mo
$329/mo
Tirzepatide / year (modeled)
Better on this row: $2,988
$3,948
Oral semaglutide / month
Not listed
$249/mo
Oral tirzepatide / month
Not listed
$349/mo
Brand Wegovy / Ozempic / month
Not listed
$1,299/mo
Brand Zepbound / Mounjaro / month
Not listed
$1,069/mo
Coverage
State availability
50 states
50 states
Oral option listed
Not listed
Yes
Brand-name access listed
Not listed
Wegovy / Ozempic, Zepbound / Mounjaro
Included in the price
Medication, clinician visits, shipping, coaching
Medication, clinician visits, shipping, coaching
Terms & safety
Price shown
Before intake
Before intake
Cancel anytime
Yes
Yes
Minimum commitment
Plans come in 1-, 2-, 6- and 12-month lengths, and 'Every plan is billed monthly.' The FAQ says 'Pause, skip a shipment, or cancel from the patient portal anytime. No contracts, no cancellation fees, no charges for months you skip.' The site doesn't say whether leaving a longer plan early changes your rate
None
Refunds
'Federal health and safety regulations don't allow returns or refunds on prescription medications or compounded products once they've shipped.' Wrong or damaged shipments must be reported within 7 days of delivery
Not disclosed
Early-cancellation fee
None
None
FDA warning letters
1 warning letter
Better on this row: None on record
Provider facts checked
October 2026
August 2026
Every dose and plan: Belle Health · RxSpan MD
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Belle Health if…
- About $600 a year less than RxSpan MD for compounded semaglutide at standing prices
- Flat pricing that doesn't rise as your dose goes up, with no membership or consultation fee
- Weekly check-ins with a registered dietitian are included in weight-loss plans
What to weigh up
- 1 FDA warning letter on record
- FDA Warning Letter (Feb 2026) for misbranding compounded GLP-1 products

Choose RxSpan MD if…
- Lists oral compounded semaglutide, oral compounded tirzepatide and brand-name Wegovy / Ozempic, which Belle Health doesn't price
- No FDA warning letters on record (Belle Health has 1)
- Physician-led — founded by Dr. John Diaz, a board-certified plastic surgeon with 20+ years' experience
What to weigh up
- About $600 a year more than Belle Health for compounded semaglutide
- Compounded pricing ($249 semaglutide / $329 tirzepatide) sits mid-to-high versus the cheapest telehealth options
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Belle Health
7.6/10
RxSpan MD
8.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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From $299/mo
Get started →SkinnyRx
Compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price
Read full review →From $149.25/mo
Get started →Collective
The lowest flat medication price if you can absorb an annual membership fee
Read full review →From $59/mo + membership
Get started →Belle Health vs RxSpan MD: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.