MEDVi vs RxSpan MD
In our scoring, RxSpan MD edges ahead overall (8.1 vs 7.1 out of 10), and RxSpan MD costs less for compounded semaglutide (about $600 a year less).
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Key differences
- Price
- RxSpan MD $249/mo vs MEDVi $299/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $600 a year less with RxSpan MD)
- Coverage
- MEDVi 48 states; RxSpan MD 50 states (only RxSpan MD: Mississippi and North Dakota)
- Included
- MEDVi: medication, clinician visits, shipping, coaching; RxSpan MD: medication, clinician visits, shipping, coaching
- Safety
- FDA warning letters on record: MEDVi 1, RxSpan MD none
MEDVi
Affiliate partnerBest for switching between compounded and brand-name GLP-1 through one provider
semaglutide
$299
$179 first month
Our score 7.1/10
RxSpan MD
Affiliate partnerBest for physician-led, pharmacy-transparent compounded GLP-1 with brand-name options
semaglutide
$249
Our score 8.1/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
MEDVi
RxSpan MD
Price
Semaglutide / month
$299/mo
$179 first month
Better on this row: $249/mo
Semaglutide / year (modeled)
$3,588
Better on this row: $2,988
Oral semaglutide / month
$249/mo
$249/mo
Oral semaglutide / year (modeled)
$2,988
$2,988
Tirzepatide / month
Not listed
$329/mo
Oral tirzepatide / month
Not listed
$349/mo
Brand Wegovy / Ozempic / month
Not listed
$1,299/mo
Brand Zepbound / Mounjaro / month
Not listed
$1,069/mo
Coverage
State availability
48 states
50 states
Oral option listed
Yes
Yes
Brand-name access listed
Not listed
Wegovy / Ozempic, Zepbound / Mounjaro
Included in the price
Medication, clinician visits, shipping, coaching
Medication, clinician visits, shipping, coaching
Terms & safety
Price shown
Before intake
Before intake
Lab work
Not required
Not disclosed
Video visit
Not required
Not disclosed
Cancel anytime
Not disclosed
Yes
Minimum commitment
Membership
None
Early-cancellation fee
Not disclosed
None
FDA warning letters
1 warning letter
Better on this row: None on record
Provider facts checked
August 2026
August 2026
Show where they differ by stateHide state lists
Only RxSpan MD (2 states)
- Mississippi
- North Dakota
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose MEDVi if…
- Both compounded and brand-name (Wegovy, Zepbound) GLP-1 options in one platform
- Oral tablet and injectable formats
- Named US pharmacy partners (Triad Rx, Precision Medicine, RedRock Pharmacy, Beaker Pharmacy & Compounding)
What to weigh up
- 1 FDA warning letter on record
- About $600 a year more than RxSpan MD for compounded semaglutide
Choose RxSpan MD if…
- About $600 a year less than MEDVi for compounded semaglutide at standing prices
- Lists compounded tirzepatide, oral compounded tirzepatide and brand-name Wegovy / Ozempic, which MEDVi doesn't price
- Serves Mississippi and North Dakota, where MEDVi doesn't
What to weigh up
- Compounded pricing ($249 semaglutide / $329 tirzepatide) sits mid-to-high versus the cheapest telehealth options
- Brand-name GLP-1 is priced steeply (Wegovy $1,349, Ozempic $1,299, Zepbound $1,069)
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
MEDVi
7.1/10
RxSpan MD
8.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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Collective
The lowest flat medication price if you can absorb an annual membership fee
Read full review →From $59/mo + membership
Get started →From $219/mo
Get started →Found
Compounded GLP-1 with medication included from $169/mo cash, plus insurance help for brand GLP-1s
Read full review →From $169/mo
Get started →MEDVi vs RxSpan MD: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.