RxSpan MD vs Sesame Care
In our scoring, RxSpan MD edges ahead overall (8.1 vs 8.0 out of 10), and Sesame Care costs less for brand-name Wegovy / Ozempic (about $11,400 a year less).
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Key differences
- Price
- Sesame Care $349/mo vs RxSpan MD $1,299/mo for brand-name Wegovy / Ozempic (standing prices, no prepay or separate membership listed · about $11,400 a year less with Sesame Care)
- Coverage
- RxSpan MD 50 states (Sesame Care doesn't publish a state list)
- Included
- RxSpan MD: medication, clinician visits, shipping, coaching; Sesame Care: not stated
RxSpan MD
Affiliate partnerBest for physician-led, pharmacy-transparent compounded GLP-1 with brand-name options
semaglutide
$249
Our score 8.1/10
Sesame Care
Affiliate partnerBest for Brand-name GLP-1s at cash prices, no compounding
Brand-name Wegovy / Ozempic
$349
$199 first month
Our score 8.0/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
RxSpan MD
Sesame Care
Price
Brand Wegovy / Ozempic / month
$1,299/mo
Better on this row: $349/mo
$199 first month
Brand Wegovy / Ozempic / year (modeled)
$15,588
Better on this row: $4,188
Brand Zepbound / Mounjaro / month
$1,069/mo
Better on this row: $299/mo
Brand Zepbound / Mounjaro / year (modeled)
$12,828
Better on this row: $3,588
Semaglutide / month
$249/mo
Not listed
Tirzepatide / month
$329/mo
Not listed
Oral semaglutide / month
$249/mo
Not listed
Oral tirzepatide / month
$349/mo
Not listed
Brand Wegovy pill / Rybelsus / month
Not listed
$149/mo
Brand Foundayo / month
Not listed
$149/mo
Coverage
State availability
50 states
List not published
Oral option listed
Yes
Yes
Brand-name access listed
Wegovy / Ozempic, Zepbound / Mounjaro
Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo
Included in the price
Medication, clinician visits, shipping, coaching
Not disclosed
Terms & safety
Price shown
Before intake
Before intake
Video visit
Not disclosed
Required
Cancel anytime
Yes
Yes
Minimum commitment
None
None
Early-cancellation fee
None
None
FDA warning letters
None on record
None on record
Provider facts checked
August 2026
August 2026
Every dose and plan: RxSpan MD · Sesame Care
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose RxSpan MD if…
- Lists compounded semaglutide, compounded tirzepatide and oral compounded semaglutide, which Sesame Care doesn't price
- Publishes its full state list (50 states)
- Physician-led — founded by Dr. John Diaz, a board-certified plastic surgeon with 20+ years' experience
What to weigh up
- About $11,400 a year more than Sesame Care for brand-name Wegovy / Ozempic
- Compounded pricing ($249 semaglutide / $329 tirzepatide) sits mid-to-high versus the cheapest telehealth options
Choose Sesame Care if…
- About $11,400 a year less than RxSpan MD for brand-name Wegovy / Ozempic at standing prices
- Lists brand-name Wegovy pill / Rybelsus and brand-name Foundayo, which RxSpan MD doesn't price
- Marketplace transparency — pick a named provider with a displayed price before booking, unlike most opaque telehealth intake
What to weigh up
- No published state list; confirm yours at signup
- Marketplace model means clinician credentials and quality vary provider to provider
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
RxSpan MD
8.1/10
Sesame Care
8.0/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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SkinnyRx
Compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price
Read full review →From $149.25/mo
Get started →Collective
The lowest flat medication price if you can absorb an annual membership fee
Read full review →From $59/mo + membership
Get started →From $219/mo
Get started →RxSpan MD vs Sesame Care: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.