Luvo Health vs RxSpan MD
In our scoring, RxSpan MD edges ahead overall (8.1 vs 7.5 out of 10), and Luvo Health costs less for compounded semaglutide (about $661 a year less; one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost).
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Key differences
- Price
- Luvo Health $179/mo vs RxSpan MD $249/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $661 a year less with Luvo Health · one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- Coverage
- RxSpan MD 50 states (Luvo Health doesn't publish a state list)
- Included
- Luvo Health: medication, clinician visits, shipping; RxSpan MD: medication, clinician visits, shipping, coaching

Luvo Health
Affiliate partnerBest for compounded and brand GLP-1s, oral tablets and microdosing on one public price list
semaglutide
$179
billed every 4 weeks · $99 first month
Our score 7.5/10

RxSpan MD
Affiliate partnerBest for physician-led, pharmacy-transparent compounded GLP-1 with brand-name options
semaglutide
$249
Our score 8.1/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Luvo Health
RxSpan MD
Price
Semaglutide / month
Better on this row: $179/mo
billed every 4 weeks · $99 first month
$249/mo
Semaglutide / year (modeled)
Better on this row: $2,327
13 charges
$2,988
Tirzepatide / month
Better on this row: $179/mo
billed every 4 weeks · $99 first month
$329/mo
Tirzepatide / year (modeled)
Better on this row: $2,327
13 charges
$3,948
Oral semaglutide / month
Better on this row: $179/mo
billed every 4 weeks · $99 first month
$249/mo
Oral semaglutide / year (modeled)
Better on this row: $2,327
13 charges
$2,988
Brand Wegovy / Ozempic / month
$1,299/mo
billed every 4 weeks
Better on this row: $1,299/mo
Brand Wegovy / Ozempic / year (modeled)
$16,887
13 charges
Better on this row: $15,588
Brand Zepbound / Mounjaro / month
$1,399/mo
billed every 4 weeks
Better on this row: $1,069/mo
Brand Zepbound / Mounjaro / year (modeled)
$18,187
13 charges
Better on this row: $12,828
Oral tirzepatide / month
Not listed
$349/mo
Coverage
State availability
List not published
50 states
Oral option listed
Yes
Yes
Brand-name access listed
Wegovy / Ozempic, Zepbound / Mounjaro
Wegovy / Ozempic, Zepbound / Mounjaro
Included in the price
Medication, clinician visits, shipping
Medication, clinician visits, shipping, coaching
Terms & safety
Price shown
Before intake
Before intake
Cancel anytime
Yes
Yes
Minimum commitment
None on the 4-week plan; the pricing page mentions plans up to 24 weeks but publishes only 4-week prices
None
Refunds
You may request or be issued a refund for your current billing cycle only if, at the time of the request or cancellation, your medication has not been ordered.
Not disclosed
Early-cancellation fee
None
None
FDA warning letters
None on record
None on record
Provider facts checked
October 2026
August 2026
Every dose and plan: Luvo Health · RxSpan MD
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.

Choose Luvo Health if…
- About $661 a year less than RxSpan MD for compounded semaglutide at standing prices (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- Every medication's 4-week price is published openly, with no intake or account needed
- Offers both compounded GLP-1s and brand-name Ozempic and Zepbound in one place
What to weigh up
- No published state list; confirm yours at signup
- Billed every 28 days, not per month, which is 13 charges a year rather than 12

Choose RxSpan MD if…
- Lists oral compounded tirzepatide, which Luvo Health doesn't price
- Publishes its full state list (50 states)
- Physician-led — founded by Dr. John Diaz, a board-certified plastic surgeon with 20+ years' experience
What to weigh up
- About $661 a year more than Luvo Health for compounded semaglutide (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- Compounded pricing ($249 semaglutide / $329 tirzepatide) sits mid-to-high versus the cheapest telehealth options
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Luvo Health
7.5/10
RxSpan MD
8.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Ready to start? Vetted GLP-1 providers
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Collective
The lowest flat medication price if you can absorb an annual membership fee
Read full review →From $59/mo + membership
Get started →From $219/mo
Get started →Found
Compounded GLP-1 with medication included from $169/mo cash, plus insurance help for brand GLP-1s
Read full review →From $169/mo
Get started →Luvo Health vs RxSpan MD: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.