Live Vital vs RxSpan MD
In our scoring, RxSpan MD edges ahead overall (8.1 vs 7.7 out of 10), and Live Vital costs less for compounded semaglutide (about $1,428 a year less).
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
Key differences
- Price
- Live Vital $130/mo vs RxSpan MD $249/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $1,428 a year less with Live Vital)
- Coverage
- Both serve the same 50 states
- Included
- Live Vital: medication, clinician visits, shipping; RxSpan MD: medication, clinician visits, shipping, coaching
Live Vital
Affiliate partnerBest for low-cost, physician-led compounded GLP-1 with peptide and hormone options
semaglutide
$130
$99 first month
Our score 7.7/10
RxSpan MD
Affiliate partnerBest for physician-led, pharmacy-transparent compounded GLP-1 with brand-name options
semaglutide
$249
Our score 8.1/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Live Vital
RxSpan MD
Price
Semaglutide / month
Better on this row: $130/mo
$99 first month
$249/mo
Semaglutide / year (modeled)
Better on this row: $1,560
$2,988
Tirzepatide / month
Better on this row: $239/mo
$183 first month
$329/mo
Tirzepatide / year (modeled)
Better on this row: $2,868
$3,948
Oral semaglutide / month
Not listed
$249/mo
Oral tirzepatide / month
Not listed
$349/mo
Brand Wegovy / Ozempic / month
Not listed
$1,299/mo
Brand Zepbound / Mounjaro / month
Not listed
$1,069/mo
Coverage
State availability
50 states
50 states
Oral option listed
Not listed
Yes
Brand-name access listed
Not listed
Wegovy / Ozempic, Zepbound / Mounjaro
Included in the price
Medication, clinician visits, shipping
Medication, clinician visits, shipping, coaching
Terms & safety
Price shown
Before intake
Before intake
Lab work
Not required
Not disclosed
Video visit
Not required
Not disclosed
Cancel anytime
Yes
Yes
Minimum commitment
Sold as 10-week protocols
None
Refunds
Terms section 7: 'You may cancel at any time. Cancellation will be effective at the end of your current billing period. Refunds for consultations are provided at our discretion. Medications and lab work are generally non-refundable once ordered or dispensed.'
Not disclosed
Early-cancellation fee
Not disclosed
None
FDA warning letters
None on record
None on record
Provider facts checked
August 2026
August 2026
Every dose and plan: Live Vital · RxSpan MD
Get alerted when GLP-1 prices drop
Join the GLP-1 price-watch list — we re-verify 540+ providers' prices on their own sites and email you when tracked prices move.
Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Live Vital if…
- About $1,428 a year less than RxSpan MD for compounded semaglutide at standing prices
- Physician-led — founded by Dr. Patrick Taylor, MD; all treatments doctor-prescribed via the clinical team
- Every plan includes doctor prescribing, licensed-pharmacy medication, and direct-to-door shipping
What to weigh up
- The advertised '/mo' rate divides a 10-week protocol by three, so a calendar month really costs about $130 or $239
- Doesn't accept insurance (HSA/FSA funds only)
Choose RxSpan MD if…
- Lists oral compounded semaglutide, oral compounded tirzepatide and brand-name Wegovy / Ozempic, which Live Vital doesn't price
- Physician-led — founded by Dr. John Diaz, a board-certified plastic surgeon with 20+ years' experience
- Names its 503A pharmacy partners (Belmar, Strive, Epiq Scripts, Casa Pharma) and medical group
What to weigh up
- About $1,428 a year more than Live Vital for compounded semaglutide
- Compounded pricing ($249 semaglutide / $329 tirzepatide) sits mid-to-high versus the cheapest telehealth options
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Live Vital
7.7/10
RxSpan MD
8.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
From $299/mo
Get started →SkinnyRx
Compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price
Read full review →From $149.25/mo
Get started →Collective
The lowest flat medication price if you can absorb an annual membership fee
Read full review →From $59/mo + membership
Get started →Live Vital vs RxSpan MD: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring Live Vital and RxSpan MD head-to-heads in the same category.
- Live Vital vs Amazon One Medical
- Live Vital vs Vytora Health
- Live Vital vs CoreAge Rx
- RxSpan MD vs Amazon One Medical
- RxSpan MD vs Vytora Health
- RxSpan MD vs CoreAge Rx
Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.