AgelessRx vs RxSpan MD
In our scoring, RxSpan MD edges ahead overall (8.1 vs 7.1 out of 10), and AgelessRx costs less for compounded semaglutide (about $1,080 a year less).
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Key differences
- Price
- AgelessRx $159/mo vs RxSpan MD $249/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $1,080 a year less with AgelessRx)
- Coverage
- RxSpan MD 50 states (AgelessRx doesn't publish a state list)
- Included
- AgelessRx: medication, clinician visits, shipping; RxSpan MD: medication, clinician visits, shipping, coaching
AgelessRx
Affiliate partnerBest for longevity-focused GLP-1 care with microdosing and brand-name options
semaglutide
$159
Our score 7.1/10
RxSpan MD
Affiliate partnerBest for physician-led, pharmacy-transparent compounded GLP-1 with brand-name options
semaglutide
$249
Our score 8.1/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
AgelessRx
RxSpan MD
Price
Semaglutide / month
Better on this row: $159/mo
$249/mo
Semaglutide / year (modeled)
Better on this row: $1,908
$2,988
Tirzepatide / month
Better on this row: $209/mo
$109 first month
$329/mo
Tirzepatide / year (modeled)
Better on this row: $2,508
$3,948
Brand Wegovy / Ozempic / month
Better on this row: $414/mo
$264 first month
$1,299/mo
Brand Wegovy / Ozempic / year (modeled)
Better on this row: $4,968
$15,588
Brand Zepbound / Mounjaro / month
Better on this row: $514/mo
$364 first month
$1,069/mo
Brand Zepbound / Mounjaro / year (modeled)
Better on this row: $6,168
$12,828
Oral semaglutide / month
Not listed
$249/mo
Oral tirzepatide / month
Not listed
$349/mo
Brand Wegovy pill / Rybelsus / month
$349/mo
$199 first month
Not listed
Coverage
State availability
List not published
50 states
Oral option listed
Yes
Yes
Brand-name access listed
Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus
Wegovy / Ozempic, Zepbound / Mounjaro
Included in the price
Medication, clinician visits, shipping
Medication, clinician visits, shipping, coaching
Terms & safety
Price shown
Before intake
Before intake
Cancel anytime
Yes
Yes
Minimum commitment
Monthly, 2-month and 4-month plans; the lowest advertised compounded prices require the 4-month plan billed in full
None
Refunds
FAQ: 'AgelessRx cannot guarantee refunds for any cancellation requests received after our pharmacy partner has received your order... does not accept returns nor can we offer any refunds for any prescription product once it has left our pharmacy partner.'
Not disclosed
Early-cancellation fee
Not disclosed
None
FDA warning letters
None on record
None on record
Provider facts checked
October 2026
August 2026
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose AgelessRx if…
- About $1,080 a year less than RxSpan MD for compounded semaglutide at standing prices
- Lists brand-name Wegovy pill / Rybelsus, which RxSpan MD doesn't price
- Named, in-house medical team led by a medical director, with care based in Ann Arbor, MI
What to weigh up
- No published state list; confirm yours at signup
- The lowest prices need a 4-month plan; microdose tirzepatide jumps from $109 to $209/mo after month one
Choose RxSpan MD if…
- Lists oral compounded semaglutide and oral compounded tirzepatide, which AgelessRx doesn't price
- Publishes its full state list (50 states)
- Physician-led — founded by Dr. John Diaz, a board-certified plastic surgeon with 20+ years' experience
What to weigh up
- About $1,080 a year more than AgelessRx for compounded semaglutide
- Compounded pricing ($249 semaglutide / $329 tirzepatide) sits mid-to-high versus the cheapest telehealth options
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
AgelessRx
7.1/10
RxSpan MD
8.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
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Found
Compounded GLP-1 with medication included from $169/mo cash, plus insurance help for brand GLP-1s
Read full review →From $169/mo
Get started →GobyMeds
No-membership, no-auto-renew compounded GLP-1 orders, from about $99/mo on a 3-month bundle
Read full review →From $169/mo
Get started →Ivim Health
Compounded GLP-1 with weekly provider check-ins and health coaches, under a required monthly membership
Read full review →From $65/mo + membership
Get started →AgelessRx vs RxSpan MD: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.