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CoreAge Rx vs RxSpan MD

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
CoreAge Rx logo

CoreAge Rx

8.3
★★★★4.2/5

Best for: best overall value

Visit CoreAge Rx
VS
RxSpan MD logo

RxSpan MD

8.1
★★★★4.1/5

Best for: shoppers wanting physician-led, pharmacy-transparent compounded GLP-1 with brand-name options

Visit RxSpan MD

CoreAge Rx and RxSpan MD are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, CoreAge Rx starts lower at $149/mo versus $249/mo, and RxSpan MD is the option we'd start with for most patients. Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

CoreAge Rx

0.25mgCompounded
$149/mo
semaglutide
0.5mgCompounded
$199/mo
semaglutide
1mgCompounded
$249/mo
semaglutide
1.7mgCompounded
$299/mo
semaglutide
2.5mgCompounded
$349/mo
tirzepatide

RxSpan MD

Semaglutide InjectionCompounded
$249$194/mo
Save 22% right now
semaglutide

Plan ladder: Monthly $249/mo, 3-mo $219/mo, 6-mo $199/mo, 12-mo $194/mo. Card labeled '(For the first month)'; plan picker shows flat recurring rates (Total if prescribed $657 on 3-mo).

Semaglutide CapsulesCompounded
$249$179/mo
Save 28% right now
semaglutide

Plan ladder: Monthly $249/mo, 3-mo $219/mo, 6-mo $199/mo, 12-mo $179/mo.

Tirzepatide InjectionCompounded
$329$269/mo
Save 18% right now
tirzepatide

Plan ladder: Monthly $329/mo, 3-mo $309/mo, 6-mo $289/mo, 12-mo $269/mo (Total if prescribed $927 on 3-mo).

Tirzepatide CapsulesCompounded
$349$269/mo
Save 23% right now
tirzepatide

Plan ladder: Monthly $349/mo, 3-mo $299/mo, 6-mo $289/mo, 12-mo $269/mo (Total if prescribed $897 on 3-mo).

ZepboundBrand-name
$1069/mo
tirzepatide

Monthly plan only ($1,069/mo).

OzempicBrand-name
$1299/mo
semaglutide

Monthly plan only ($1,299/mo).

WegovyBrand-name
$1349/mo
semaglutide

Monthly plan only ($1,349/mo).

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What’s included

CoreAge Rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

RxSpan MD

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Included

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

CoreAge Rx

8.3/10

Overall

RxSpan MD

8.1/10

Value25%

8.5A
vs
B
7.0

Effectiveness25%

8.5A
vs
B
8.5

User Experience15%

8.5A
vs
B
7.5

Trust & Safety15%

7.8A
vs
B
9.3

Accessibility10%

8.0A
vs
B
8.5

Support10%

8.4A
vs
B
8.9

Features & Coverage

FeatureCoreAge RxRxSpan MD
Starting Price$149/mo$249/mo
Features6 features7 features
States Available5050
Compounded✓ Yes✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About CoreAge Rx

CoreAge Rx offers LegitScript-verified compounded semaglutide and tirzepatide with free 2-day shipping to all 50 states. Backed by licensed physicians and 24/7 support, it delivers the most competitive pricing in the compounded GLP-1 space.

Read our full CoreAge Rx review →

About RxSpan MD

RxSpan MD is a physician-led telehealth practice founded by Dr. John Diaz, a board-certified plastic surgeon, offering compounded GLP-1 weight loss — semaglutide and tirzepatide from $249/mo, as injections or oral capsules — plus brand-name Wegovy, Zepbound and Ozempic. It's unusually transparent: it names its 503A pharmacy partners (Belmar, Strive, Epiq Scripts, Casa Pharma) and medical group, ships free, and includes unlimited 24/7 support. Available in all 50 states.

Read our full RxSpan MD review →

Pros & Cons

CoreAge Rx

What we like

  • LegitScript certified — rigorous pharmacy standards
  • Free 2-day shipping nationwide
  • Both semaglutide and tirzepatide available
  • Lowest per-month pricing in the compounded segment
  • 24/7 support team
  • All 50 states covered

Watch-outs

  • Compounded only — no brand-name Ozempic or Wegovy
  • Newer brand with fewer independent reviews than legacy players

RxSpan MD

What we like

  • Physician-led — founded by Dr. John Diaz, a board-certified plastic surgeon with 20+ years' experience
  • Compounded semaglutide and tirzepatide from $249/mo (injection or oral capsules), plus brand-name Wegovy, Zepbound and Ozempic
  • Names its 503A pharmacy partners (Belmar, Strive, Epiq Scripts, Casa Pharma) and medical group
  • LegitScript-certified (#50405601); free expedited shipping and unlimited 24/7 support included
  • Available in all 50 states via a 2-minute assessment

Watch-outs

  • Compounded pricing ($249 semaglutide / $329 tirzepatide) sits mid-to-high versus the cheapest telehealth options
  • Brand-name GLP-1 is priced steeply (Wegovy $1,349, Ozempic $1,299, Zepbound $1,069)
  • Multi-vertical practice (also hair, sexual health, longevity), not weight-loss-only
  • Legal entity name isn't published on the site

Our Verdict

Winner: RxSpan MD

RxSpan MD is our recommended choice here, particularly for shoppers wanting physician-led, pharmacy-transparent compounded GLP-1 with brand-name options. CoreAge Rx is a solid alternative, especially if you want best overall value — compare the six-dimension breakdown and pricing below to weigh them for your situation.

Choose CoreAge Rx if…

You want best overall value and a starting price around $149/mo.

Choose RxSpan MD if…

You want shoppers wanting physician-led, pharmacy-transparent compounded GLP-1 with brand-name options and a starting price around $249/mo.

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CoreAge Rx vs RxSpan MD: FAQ

Key terms, explained

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.