CoreAge Rx vs RxSpan MD
In our scoring, CoreAge Rx edges ahead overall (8.3 vs 8.1 out of 10), and CoreAge Rx costs less for compounded semaglutide (about $2,040 a year less).
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Key differences
- Price
- CoreAge Rx $79/mo vs RxSpan MD $249/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $2,040 a year less with CoreAge Rx)
- Coverage
- Both serve the same 50 states
- Included
- CoreAge Rx: medication, clinician visits, shipping; RxSpan MD: medication, clinician visits, shipping, coaching

CoreAge Rx
Affiliate partnerBest for lowest-price compounded semaglutide and tirzepatide with one flat price at every dose
semaglutide
$79
Our score 8.3/10

RxSpan MD
Affiliate partnerBest for physician-led, pharmacy-transparent compounded GLP-1 with brand-name options
semaglutide
$249
Our score 8.1/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
CoreAge Rx
RxSpan MD
Price
Semaglutide / month
Better on this row: $79/mo
$249/mo
Semaglutide / year (modeled)
Better on this row: $948
$2,988
Tirzepatide / month
Better on this row: $129/mo
$329/mo
Tirzepatide / year (modeled)
Better on this row: $1,548
$3,948
Oral semaglutide / month
Not listed
$249/mo
Oral tirzepatide / month
Not listed
$349/mo
Brand Wegovy / Ozempic / month
Not listed
$1,299/mo
Brand Zepbound / Mounjaro / month
Not listed
$1,069/mo
Coverage
State availability
50 states
50 states
Oral option listed
Not listed
Yes
Brand-name access listed
Not listed
Wegovy / Ozempic, Zepbound / Mounjaro
Included in the price
Medication, clinician visits, shipping
Medication, clinician visits, shipping, coaching
Terms & safety
Price shown
Before intake
Before intake
Cancel anytime
Yes
Yes
Minimum commitment
No long-term contracts; one-time purchases and auto-renewing subscriptions are both offered
None
Refunds
Full refund of the medication portion if a provider finds you ineligible, minus a non-refundable $50-$100 consultation fee; no refunds once approved or sent to the pharmacy, and all orders become non-refundable 30 days after purchase.
Not disclosed
Early-cancellation fee
Not disclosed
None
FDA warning letters
None on record
None on record
Provider facts checked
October 2026
August 2026
Every dose and plan: CoreAge Rx · RxSpan MD
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.

Choose CoreAge Rx if…
- About $2,040 a year less than RxSpan MD for compounded semaglutide at standing prices
- Same price at every dose, so your bill doesn't rise as your dose goes up
- No membership fee; medication and shipping are included in the price
What to weigh up
- Trustpilot has suspended its rating for a breach of guidelines after removing a number of fake reviews
- A 'Fall Sale' countdown timer showed nearly the same time left on two separate visits

Choose RxSpan MD if…
- Lists oral compounded semaglutide, oral compounded tirzepatide and brand-name Wegovy / Ozempic, which CoreAge Rx doesn't price
- Physician-led — founded by Dr. John Diaz, a board-certified plastic surgeon with 20+ years' experience
- Names its 503A pharmacy partners (Belmar, Strive, Epiq Scripts, Casa Pharma) and medical group
What to weigh up
- About $2,040 a year more than CoreAge Rx for compounded semaglutide
- Compounded pricing ($249 semaglutide / $329 tirzepatide) sits mid-to-high versus the cheapest telehealth options
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
CoreAge Rx
8.3/10
RxSpan MD
8.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Ready to start? Vetted GLP-1 providers
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Ivim Health
Compounded GLP-1 with weekly provider check-ins and health coaches, under a required monthly membership
Read full review →From $65/mo + membership
Get started →From $247/mo
Get started →From $139/mo
Get started →CoreAge Rx vs RxSpan MD: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.