RxSpan MD vs Sprout Health
In our scoring, RxSpan MD edges ahead overall (8.1 vs 7.6 out of 10), and Sprout Health costs less for compounded semaglutide (about $1,200 a year less).
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Key differences
- Price
- Sprout Health $149/mo vs RxSpan MD $249/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $1,200 a year less with Sprout Health)
- Coverage
- RxSpan MD 50 states; Sprout Health 44 states (only RxSpan MD: Alabama, Arkansas, California and 3 more)
- Included
- RxSpan MD: medication, clinician visits, shipping, coaching; Sprout Health: medication
- Safety
- FDA warning letters on record: RxSpan MD none, Sprout Health 1
RxSpan MD
Affiliate partnerBest for physician-led, pharmacy-transparent compounded GLP-1 with brand-name options
semaglutide
$249
Our score 8.1/10
Sprout Health
Affiliate partnerBest for LegitScript-certified compounded GLP-1 via named pharmacies
semaglutide
$149
Our score 7.6/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
RxSpan MD
Sprout Health
Price
Semaglutide / month
$249/mo
Better on this row: $149/mo
Semaglutide / year (modeled)
$2,988
Better on this row: $1,788
Tirzepatide / month
$329/mo
Better on this row: $199/mo
Tirzepatide / year (modeled)
$3,948
Better on this row: $2,388
Brand Wegovy / Ozempic / month
Better on this row: $1,299/mo
$1,799/mo
Brand Wegovy / Ozempic / year (modeled)
Better on this row: $15,588
$21,588
Brand Zepbound / Mounjaro / month
Better on this row: $1,069/mo
$1,999/mo
Brand Zepbound / Mounjaro / year (modeled)
Better on this row: $12,828
$23,988
Oral semaglutide / month
$249/mo
Not listed
Oral tirzepatide / month
$349/mo
Not listed
Coverage
State availability
50 states
44 states
Oral option listed
Yes
Not listed
Brand-name access listed
Wegovy / Ozempic, Zepbound / Mounjaro
Wegovy / Ozempic, Zepbound / Mounjaro
Included in the price
Medication, clinician visits, shipping, coaching
Medication
Terms & safety
Price shown
Before intake
Before intake
Cancel anytime
Yes
Not disclosed
Minimum commitment
None
Not disclosed
Refunds
Not disclosed
Non-refundable unless disqualified
Early-cancellation fee
None
Not disclosed
FDA warning letters
Better on this row: None on record
1 warning letter
Provider facts checked
August 2026
August 2026
Show where they differ by stateHide state lists
Only RxSpan MD (6 states)
- Alabama
- Arkansas
- California
- Louisiana
- Mississippi
- North Dakota
Every dose and plan: RxSpan MD · Sprout Health
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose RxSpan MD if…
- Lists oral compounded semaglutide and oral compounded tirzepatide, which Sprout Health doesn't price
- Serves 6 states that Sprout Health doesn't
- No FDA warning letters on record (Sprout Health has 1)
What to weigh up
- About $1,200 a year more than Sprout Health for compounded semaglutide
- Compounded pricing ($249 semaglutide / $329 tirzepatide) sits mid-to-high versus the cheapest telehealth options
Choose Sprout Health if…
- About $1,200 a year less than RxSpan MD for compounded semaglutide at standing prices
- LegitScript certification confirmed
- 44-state coverage via a pre-qualification quiz and licensed clinician review
What to weigh up
- 1 FDA warning letter on record
- Not available in 6 states that RxSpan MD serves
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
RxSpan MD
8.1/10
Sprout Health
7.6/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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From $299/mo
Get started →SkinnyRx
Compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price
Read full review →From $149.25/mo
Get started →Collective
The lowest flat medication price if you can absorb an annual membership fee
Read full review →From $59/mo + membership
Get started →RxSpan MD vs Sprout Health: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.