HealthRX vs RxSpan MD
In our scoring, RxSpan MD edges ahead overall (8.1 vs 7.3 out of 10), and HealthRX costs less for compounded semaglutide (about $1,008 a year less).
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Key differences
- Price
- HealthRX $165/mo vs RxSpan MD $249/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $1,008 a year less with HealthRX)
- Coverage
- RxSpan MD 50 states (HealthRX doesn't publish a state list)
- Included
- HealthRX: medication, clinician visits, shipping; RxSpan MD: medication, clinician visits, shipping, coaching
HealthRX
Affiliate partnerBest for flat-price compounded GLP-1, LegitScript-certified cash-pay program
semaglutide
$165
Our score 7.3/10
RxSpan MD
Affiliate partnerBest for physician-led, pharmacy-transparent compounded GLP-1 with brand-name options
semaglutide
$249
Our score 8.1/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
HealthRX
RxSpan MD
Price
Semaglutide / month
Better on this row: $165/mo
$249/mo
Semaglutide / year (modeled)
Better on this row: $1,980
$2,988
Tirzepatide / month
Better on this row: $214/mo
$329/mo
Tirzepatide / year (modeled)
Better on this row: $2,568
$3,948
Oral semaglutide / month
Not listed
$249/mo
Oral tirzepatide / month
Not listed
$349/mo
Brand Wegovy / Ozempic / month
Not listed
$1,299/mo
Brand Zepbound / Mounjaro / month
Not listed
$1,069/mo
Coverage
State availability
List not published
50 states
Oral option listed
Not listed
Yes
Brand-name access listed
Not listed
Wegovy / Ozempic, Zepbound / Mounjaro
Included in the price
Medication, clinician visits, shipping
Medication, clinician visits, shipping, coaching
FSA/HSA accepted
Yes
Not listed
Terms & safety
Price shown
Before intake
Before intake
Cancel anytime
Yes
Yes
Minimum commitment
None
None
Refunds
Refund if not approved; unshipped doses refunded
Not disclosed
Early-cancellation fee
None
None
FDA warning letters
None on record
None on record
Provider facts checked
August 2026
August 2026
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose HealthRX if…
- About $1,008 a year less than RxSpan MD for compounded semaglutide at standing prices
- Accepts FSA/HSA cards
- LegitScript-certified (certificate 50087439) and posts the FDA compounded disclaimer — real trust signals for a compounded-GLP-1 program
What to weigh up
- No published state list; confirm yours at signup
- Doesn't publicly name its 503A compounding pharmacy — you can't check that part of the supply chain yourself
Choose RxSpan MD if…
- Lists oral compounded semaglutide, oral compounded tirzepatide and brand-name Wegovy / Ozempic, which HealthRX doesn't price
- Publishes its full state list (50 states)
- Physician-led — founded by Dr. John Diaz, a board-certified plastic surgeon with 20+ years' experience
What to weigh up
- About $1,008 a year more than HealthRX for compounded semaglutide
- Compounded pricing ($249 semaglutide / $329 tirzepatide) sits mid-to-high versus the cheapest telehealth options
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
HealthRX
7.3/10
RxSpan MD
8.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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From $139/mo
Get started →From $299/mo
Get started →SkinnyRx
Compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price
Read full review →From $149.25/mo
Get started →HealthRX vs RxSpan MD: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.