DudeMeds vs RxSpan MD
In our scoring, RxSpan MD edges ahead overall (8.1 vs 6.9 out of 10), and DudeMeds costs less for compounded semaglutide (about $600 a year less).
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Key differences
- Price
- DudeMeds $199/mo vs RxSpan MD $249/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $600 a year less with DudeMeds)
- Coverage
- RxSpan MD 50 states (DudeMeds doesn't publish a state list)
- Included
- DudeMeds: medication, clinician visits, shipping; RxSpan MD: medication, clinician visits, shipping, coaching
DudeMeds
Affiliate partnerBest for men seeking no-fee compounded or brand-name GLP-1 injections
semaglutide
$199
Our score 6.9/10
RxSpan MD
Affiliate partnerBest for physician-led, pharmacy-transparent compounded GLP-1 with brand-name options
semaglutide
$249
Our score 8.1/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
DudeMeds
RxSpan MD
Price
Semaglutide / month
Better on this row: $199/mo
$249/mo
Semaglutide / year (modeled)
Better on this row: $2,388
$2,988
Tirzepatide / month
Better on this row: $233/mo
$329/mo
Tirzepatide / year (modeled)
Better on this row: $2,796
$3,948
Brand Wegovy / Ozempic / month
$1,585/mo
on a 3-month prepaid plan
$1,299/mo
Brand Wegovy / Ozempic / year (modeled)
$19,020
$15,588
Brand Zepbound / Mounjaro / month
$1,350/mo
on a 3-month prepaid plan
$1,069/mo
Brand Zepbound / Mounjaro / year (modeled)
$16,200
$12,828
Oral semaglutide / month
Not listed
$249/mo
Oral tirzepatide / month
Not listed
$349/mo
Coverage
State availability
List not published
50 states
Oral option listed
Not listed
Yes
Brand-name access listed
Wegovy / Ozempic, Zepbound / Mounjaro
Wegovy / Ozempic, Zepbound / Mounjaro
Included in the price
Medication, clinician visits, shipping
Medication, clinician visits, shipping, coaching
FSA/HSA accepted
Yes
Not listed
Terms & safety
Price shown
Before intake
Before intake
Video visit
Not required
Not disclosed
Cancel anytime
No
Better on this row: Yes
Minimum commitment
3-month minimum
None
Refunds
No refunds once shipped; damaged, wrong or late-dispatched items only
Not disclosed
Early-cancellation fee
Yes
Better on this row: None
FDA warning letters
None on record
None on record
Provider facts checked
October 2026
August 2026
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose DudeMeds if…
- About $600 a year less than RxSpan MD for compounded semaglutide at standing prices
- Accepts FSA/HSA cards
- Compounded semaglutide and tirzepatide plus brand-name Ozempic, Wegovy, Mounjaro and Zepbound
What to weigh up
- No published state list; confirm yours at signup
- Not cancel-anytime; Early-cancellation fee applies
Choose RxSpan MD if…
- Its $1,299/mo brand-name Wegovy / Ozempic price needs no prepay; DudeMeds' $1,585 needs a 3-month prepay
- Lists oral compounded semaglutide and oral compounded tirzepatide, which DudeMeds doesn't price
- Publishes its full state list (50 states)
What to weigh up
- About $600 a year more than DudeMeds for compounded semaglutide
- Compounded pricing ($249 semaglutide / $329 tirzepatide) sits mid-to-high versus the cheapest telehealth options
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
DudeMeds
6.9/10
RxSpan MD
8.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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DudeMeds vs RxSpan MD: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.