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MadeMed vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
MadeMed logo

MadeMed

7.4
★★★3.7/5

Best for: compounded GLP-1 in both injection and oral forms

Visit MadeMed
VS
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf

MadeMed and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $219/mo, and MadeMed is the option we'd start with for most patients. Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

MadeMed

Injectable — Starting (billed quarterly, flat at every dose)Compounded
$239/mo
semaglutide

Quarterly plan $239/mo (billed $717/3mo); 6-month plan drops to $199/mo (the site's 'From $199/mo'). Includes L-Carnitine; 2-month supplies.

Injectable — Starting (billed quarterly, flat at every dose)Compounded
$399/mo
tirzepatide

Quarterly $399/mo (billed $1,197/3mo); 6-month $369/mo.

Sublingual tablet — Starting (billed quarterly)Compounded · oral
$219/mo
semaglutide

Quarterly $219/mo (billed $657/3mo); 6-month $179/mo. Includes B6.

Sublingual tablet — Starting (billed quarterly)Compounded · oral
$299/mo
tirzepatide

Quarterly $299/mo (billed $897/3mo); 6-month $279/mo.

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

MadeMed

Inclusions not disclosed.

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

MadeMed

7.4/10

Overall

NewSelf

8.3/10

Value25%

7.0A
vs
B
9.0

Effectiveness25%

8.0A
vs
B
8.0

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

7.3A
vs
B
8.3

Accessibility10%

6.0A
vs
B
8.5

Support10%

7.5A
vs
B
7.9

Features & Coverage

FeatureMadeMedNewSelf
Starting Price$219/mo$100/mo
Features6 features6 features
States AvailableNot disclosed49
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About MadeMed

MadeMed is a direct-to-consumer GLP-1 telehealth platform offering compounded semaglutide and tirzepatide in both injectable and oral forms — four distinct products, giving needle-averse patients more choice than most competitors. It displays a LegitScript certification badge and publishes a customer support line, uncommon among chat-only rivals. Pricing is gated behind the product or checkout flow rather than shown publicly.

Read our full MadeMed review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

MadeMed

What we like

  • Four products — injectable and oral semaglutide and tirzepatide — giving needle-averse patients more options
  • LegitScript certification badge on the homepage
  • Customer phone support published (1-800-582-1428) — uncommon vs chat-only competitors
  • Affiliate partnership available via the Katalys network

Watch-outs

  • Pricing not shown publicly — gated behind product pages or checkout
  • Pharmacy partner not named
  • States served not disclosed
  • No named medical director or clinical leadership
  • 503A vs 503B compounding designation not specified
  • Corporate legal entity not disclosed
  • FDA compounded-medication disclaimer not visible in the page HTML
  • Governing law and arbitration venue not disclosed

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: MadeMed

MadeMed is our recommended choice here, particularly for compounded GLP-1 in both injection and oral forms. NewSelf is a solid alternative, especially if you want lowest-cost compounded GLP-1 with pharmacy quality transparency — compare the six-dimension breakdown and pricing below to weigh them for your situation.

Choose MadeMed if…

You want compounded GLP-1 in both injection and oral forms and a starting price around $219/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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MadeMed vs NewSelf: FAQ

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