Brightmeds vs NewSelf
An in-depth comparison of two leading GLP-1 Providers
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Brightmeds
Best for: compounded or brand GLP-1 bundled with TRT and peptides for men
Visit Brightmeds →
NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →Brightmeds and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, both start around $100/mo, and Brightmeds is the option we'd start with for most patients. Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Brightmeds
'Starting at $189' is the only published sema price (1-month plan per on-page comparison chart); ongoing/renewal price NOT published anywhere on public pages as of 2026-07-14 — the '$333/mo therafter' card verified 2026-06-06 has been removed. 'Save $50 on our First Order' banner active.
'Starting at $289' shown on the sema lander card and in the tirz lander's pricing-comparison image ('Tirzepatide (1-Month) $289 — Best Price! 1-Month Plan'); the tirz lander TEXT now contains no dollar prices at all — both the old '$249/mo' hero and '$397/mo therafter' card are gone. Ongoing price quiz-gated = not published.
Unchanged — page title verbatim 'Brightmeds: Choose Your TRT Goal: $75 Per Week, Free Labs'. TRT side-effect disclosures now also cover Enclomiphene and Anastrozole (new adjunct meds).
/products verbatim: '$100 Brightmeds doctor consult fee — Prescription sent to LillyDirect® or your preferred local pharmacy — You'll pay the pharmacy directly (price may vary by pharmacy)'; vials 'Medication cost is billed separately by LillyDirect®'. Drug price not published by Brightmeds.
NewSelf
All dosages same price
All dosages same price
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What’s included
Brightmeds
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Included
Coaching
Not disclosed
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Brightmeds
7.4/10
NewSelf
8.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Brightmeds | NewSelf |
|---|---|---|
| Starting Price | $100/mo | $100/mo |
| Features | ✓8 features | 6 features |
| States Available | 47 | ✓49 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About Brightmeds
Brightmeds is a multi-vertical telehealth platform bundling GLP-1 weight loss, TRT for men, and longevity peptides (sermorelin, NAD+, glutathione) under one membership. It offers both compounded GLP-1s — including microdosing protocols — and brand-name Zepbound pens and vials, a rare dual-modality mix. Compounded semaglutide starts at $189/mo and tirzepatide at $289/mo, flat-priced across doses; ongoing renewal pricing isn’t published before the intake quiz. Available in 47 states.
Read our full Brightmeds review →About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →Pros & Cons
Brightmeds
What we like
- One login covers GLP-1, TRT, peptides, and longevity — convenient for men exploring weight loss and hormones
- Offers both compounded GLP-1s and brand-name FDA-approved Zepbound (pens and vials)
- Microdosing protocols available for compounded semaglutide and tirzepatide
- Publishes the FDA compounded-medication disclaimer with explicit 503A and 503B facility mention
- Dispensing pharmacies named in Terms (Beaker Pharmacy and Red Rock Pharmacy)
- Free baseline labs for TRT clients, and a money-back guarantee if not approved
- 47-state footprint (excludes AL, AR, MS) — broader than most TRT-focused platforms
- Tirzepatide is flat-priced across all doses (starting at $289/mo) — no extra cost as you titrate up
Watch-outs
- Pricing isn't itemized on the main pages — you must click through to landers or the application flow
- Brand-name Zepbound carries a separate $100 doctor consult fee on top of drug cost
- No LegitScript certification mentioned on the site
- Named medical director not disclosed
- Trustpilot rating not independently audited
- Multi-vertical bundling can distract patients who only want GLP-1
- Ongoing renewal pricing was removed from the landers — only 'starting at' $189 (sema) and $289 (tirz) first-month prices are published
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Our Verdict
Brightmeds is our recommended choice here, particularly for compounded or brand GLP-1 bundled with TRT and peptides for men. NewSelf is a solid alternative, especially if you want lowest-cost compounded GLP-1 with pharmacy quality transparency — compare the six-dimension breakdown and pricing below to weigh them for your situation.
Choose Brightmeds if…
You want compounded or brand GLP-1 bundled with TRT and peptides for men and a starting price around $100/mo.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
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Mainstream telehealth GLP-1 access
From $99/mo
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Broadest drug catalog in the Lion MD white-label cluster
From $199/mo
Get started →RxSpan MD
Shoppers wanting physician-led, pharmacy-transparent compounded GLP-1 with brand-name options
From $179/mo
Get started →Brightmeds vs NewSelf: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.