HealthRX vs NewSelf
An in-depth comparison of two leading GLP-1 Providers
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HealthRX
Best for: flat-price compounded semaglutide or tirzepatide from a LegitScript-certified cash-pay program
Visit HealthRX →
NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →HealthRX and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $133/mo, and HealthRX is the option we'd start with for most patients. Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
HealthRX
Flat rate, same price at every dose; 3-month plan from $133/mo, 12-month plan from $99/mo
Flat rate, same price at every dose; 3-month plan from $209/mo, 12-month plan from $179/mo
NewSelf
All dosages same price
All dosages same price
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What’s included
HealthRX
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
HealthRX
7.3/10
NewSelf
8.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | HealthRX | NewSelf |
|---|---|---|
| Starting Price | $133/mo | ✓$100/mo |
| Features | 6 features | 6 features |
| States Available | Not disclosed | 49 |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | ✓ Yes | — |
| FDA Warnings | None | None |
About HealthRX
HealthRX is a cash-pay telehealth program offering compounded GLP-1 injections — semaglutide and tirzepatide — at flat, dose-independent pricing with free overnight cold shipping and no insurance. A US-licensed clinician reviews a short online assessment within 24 hours and prescribes if appropriate; medication ships from a licensed 503A compounding pharmacy within 24-48 hours. HealthRX is LegitScript-certified (Cert. 50087439) and posts the FDA compounded disclaimer, but it doesn't publicly name its compounding pharmacy, list the states where it prescribes, or name a medical director.
Read our full HealthRX review →About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →Pros & Cons
HealthRX
What we like
- LegitScript-certified (Cert. 50087439) and posts the FDA compounded disclaimer — real trust signals for a compounded-GLP-1 program
- Flat, dose-independent pricing — the price doesn't rise as you titrate up; from $99/mo semaglutide and $179/mo tirzepatide on the 12-month plan
- Free overnight cold shipping, no insurance needed, HSA/FSA eligible, and a full refund if a clinician doesn't approve you
- One-click cancellation and a refund on any unshipped dose — no phone-call retention wall
Watch-outs
- Doesn't publicly name its 503A compounding pharmacy — you can't independently verify that part of the supply chain
- Doesn't list the states where it prescribes (only an 'all 50 states' shipping claim); you learn eligibility after the assessment
- No named medical director or clinical leadership; clinicians are independent contractors, not HealthRX staff
- Compounded semaglutide and tirzepatide only — no brand-name (Wegovy/Zepbound) or oral options
- Compounded GLP-1s are not FDA-reviewed or approved — a different evidence and regulatory tier than brand-name
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Our Verdict
HealthRX is our recommended choice here, particularly for flat-price compounded semaglutide or tirzepatide from a LegitScript-certified cash-pay program. NewSelf is a solid alternative, especially if you want lowest-cost compounded GLP-1 with pharmacy quality transparency — compare the six-dimension breakdown and pricing below to weigh them for your situation.
Choose HealthRX if…
You want flat-price compounded semaglutide or tirzepatide from a LegitScript-certified cash-pay program and a starting price around $133/mo.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
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Mainstream telehealth GLP-1 access
From $99/mo
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From $199/mo
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Mainstream telehealth GLP-1 access
From $149.25/mo
Get started →HealthRX vs NewSelf: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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