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MangoRx vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
MangoRx logo

MangoRx

5.5
★★☆☆2.8/5

Best for: pending product verification

Visit MangoRx
VS
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf

MangoRx and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $269.1/mo, and MangoRx is the option we'd start with for most patients. Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

MangoRx

1–6 mg, single flat price across doses ('Your Price is Locked In')Compounded · oral
$299$269.1/mo
Save 10% right now
semaglutide

Slim = oral semaglutide + Vitamin B6, 30-day supply of daily mint-flavored ODTs. Subscribe & Save: 10% off initial and all auto-refill orders + free UPS Ground shipping; auto-refills every 25 days. Provider visit and shipping advertised as free on all orders. No injectable option, no tirzepatide product page. Insurance not accepted.

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

MangoRx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Not disclosed

Lab work

Not disclosed

Coaching

Not disclosed

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

MangoRx

5.5/10

Overall

NewSelf

8.3/10

Value25%

4.0A
vs
B
9.0

Effectiveness25%

5.5A
vs
B
8.0

User Experience15%

7.5A
vs
B
8.0

Trust & Safety15%

6.0A
vs
B
8.3

Accessibility10%

5.0A
vs
B
8.5

Support10%

6.0A
vs
B
7.9

Features & Coverage

FeatureMangoRxNewSelf
Starting Price$269.1/mo$100/mo
Features3 features6 features
States AvailableNot disclosed49
Compounded✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About MangoRx

MangoRx (Mangoceuticals) is a men's health telehealth platform offering compounded GLP-1 weight management alongside testosterone replacement therapy, ED treatment, and hair loss programs. Stub entry pending YMYL verification of the GLP-1-specific offering — pricing, states, pharmacy partners, and clinical workflow.

Read our full MangoRx review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

MangoRx

What we like

  • Men's-health telehealth that bundles GLP-1, TRT, ED, and hair care under one provider

Watch-outs

  • GLP-1 formulary, pricing tiers, states served, and pharmacy partners not yet confirmed
  • Cross-sells TRT alongside GLP-1s — weight-loss shoppers may get funneled into a broader men's-hormone program

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: MangoRx

MangoRx is our recommended choice here, particularly for pending product verification. NewSelf is a solid alternative, especially if you want lowest-cost compounded GLP-1 with pharmacy quality transparency — compare the six-dimension breakdown and pricing below to weigh them for your situation.

Choose MangoRx if…

You want pending product verification and a starting price around $269.1/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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MangoRx vs NewSelf: FAQ

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