NewSelf vs TrimRx
Our featured pick: TrimRx (affiliate partner). In our scoring, NewSelf scores 8.2 and TrimRx 7.7 out of 10.
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Key differences
- Price
- NewSelf $100/mo on a 3-month prepaid plan; TrimRx $179/mo no prepay listed (compounded semaglutide · not like-for-like, so neither is marked cheaper)
- Coverage
- NewSelf 48 states + PR (TrimRx doesn't publish a state list)
- Included
- NewSelf: medication, clinician visits, shipping; TrimRx: medication, clinician visits, shipping
- Safety
- FDA warning letters on record: NewSelf 1, TrimRx none
NewSelf
Best for lowest-cost compounded GLP-1 at one price for every dose, if a 3-month commitment works for you
semaglutide
$100
on a 3-month prepaid plan
Our score 8.2/10
TrimRx
Affiliate partnerBest for best overall value
semaglutide
$179
$149 first month
Our score 7.7/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
NewSelf
TrimRx
Price
Semaglutide / month
$100/mo
on a 3-month prepaid plan
$179/mo
$149 first month
Semaglutide / year (modeled)
$1,200
$2,148
Tirzepatide / month
$144/mo
on a 3-month prepaid plan
$259/mo
Tirzepatide / year (modeled)
$1,728
$3,108
Brand Wegovy / Ozempic / month
Not listed
$1,579/mo
Brand Zepbound / Mounjaro / month
Not listed
$1,249/mo
Coverage
State availability
48 states + PR
List not published
Brand-name access listed
Not listed
Wegovy / Ozempic, Zepbound / Mounjaro
Included in the price
Medication, clinician visits, shipping
Medication, clinician visits, shipping
Terms & safety
Price shown
Before intake
Before intake
Cancel anytime
No
Not disclosed
Minimum commitment
3-month plan for the listed price
Not disclosed
Refunds
No refunds after the doctor visit; full refund if the doctor declines; $99 fee if you cancel before the visit
Not disclosed
Early-cancellation fee
Yes
Not disclosed
FDA warning letters
1 warning letter
Better on this row: None on record
Provider facts checked
October 2026
August 2026
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose NewSelf if…
- Publishes its full state list (48 states + PR)
- Same price at every dose, so your bill doesn't rise as you titrate up
- No membership fee; the visit, medication and shipping are bundled
What to weigh up
- 1 FDA warning letter on record
- Its $100/mo compounded semaglutide price needs a 3-month prepaid plan
Choose TrimRx if…
- Its $179/mo compounded semaglutide price needs no prepay; NewSelf's $100 needs a 3-month prepay
- Lists brand-name Wegovy / Ozempic and brand-name Zepbound / Mounjaro, which NewSelf doesn't price
- No FDA warning letters on record (NewSelf has 1)
What to weigh up
- No published state list; confirm yours at signup
- Async, questionnaire-based intake — no mandatory video visit with a clinician before prescribing
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
NewSelf
8.2/10
TrimRx
7.7/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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NewSelf vs TrimRx: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.