NewSelf vs TrimRx
An in-depth comparison of two leading GLP-1 Providers
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NewSelf
Best for lowest-cost compounded GLP-1 with pharmacy quality transparencyStarting at $100/mo
TrimRx
Best for best overall valueStarting at $199/mo
Side-by-Side Comparison
| Feature | NewSelf | TrimRx |
|---|---|---|
| Overall Score | 7.8/10 | ✓9.0/10 |
| Starting Price | ✓$100/mo | $199/mo |
| Editorial Rating | 3.9 ★ /5 | ✓4.5 ★ /5 |
| Features | ✓5 features | 3 features |
| States Available | ✓49 | 0 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
NewSelf
Pros
- ✓Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- ✓All dosages at the same price — no price escalation as dose increases
- ✓LegitScript certified with 503A licensed pharmacies
- ✓Third-party potency, sterility, and endotoxicity testing
- ✓48 states + Puerto Rico coverage
- ✓B12/B6 + Glycine enhanced formulations
- ✓No membership fees
Cons
- ✗Not available in Mississippi and Louisiana
- ✗Compounded only — no brand-name options
- ✗Site also promotes AI health optimization and longevity (broader platform)
TrimRx
Pros
- ✓Both semaglutide and tirzepatide available
- ✓Compounded GLP-1 access
Cons
- ✗Limited public information on program details
Our Verdict
TrimRx edges out NewSelf with a higher overall score of 9.0/10 and is particularly strong for best overall value. NewSelf remains a solid alternative, especially if you're looking for lowest-cost compounded GLP-1 with pharmacy quality transparency.
Glossary references
Key terms in this article, linked to their canonical definitions.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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- NewSelf vs NovoCare Pharmacy
- TrimRx vs Vytora Health
- TrimRx vs Enhance MD
- TrimRx vs Noom Med
Or see the full category ranking.
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