NewSelf vs ShedRx
An in-depth comparison of two leading GLP-1 Providers
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NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →
NewSelf and ShedRx are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $169/mo, and ShedRx is the option we'd start with for most patients. Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
NewSelf
All dosages same price
All dosages same price
ShedRx
$199 1-month / $179 6-month / $159 12-month plan; promo_price = 12-month commitment rate, not a temporary promo
Starting at $229/month; 'Medication and supplies included | Member support | Free shipping' (up from $199 in our record)
Starting at $199/month, month-to-month; free shipping stated (replaces our obsolete 'Oral $349' row)
$299 1-month / $269 6-month / $239 12-month plan; promo_price = 12-month commitment rate
NEW product. $149/mo medication (cash pay, paid to dispensing pharmacy) + $125/mo Shed membership and provider fee
Page shows BOTH: FAQ 'starts at $149 (pill) and $199 (pen)... new patients using cash pay' + '$99 Shed membership', while hero states '$349-499 for the medication' + '$125/month Shed Membership'. Medication purchased directly via NovoCare; membership fee inconsistency ($99 vs $125) on same page
FAQ: 'starts at $349 per month for new patients using cash pay' + $99 membership per FAQ ($125/mo per hero); medication purchased directly via LillyDirect
Starting at $169/month; 'Includes 2 Health Coaching sessions per month'
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What’s included
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
ShedRx
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Not disclosed
Lab work
Not disclosed
Coaching
Included
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
NewSelf
8.3/10
ShedRx
8.0/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | NewSelf | ShedRx |
|---|---|---|
| Starting Price | ✓$100/mo | $169/mo |
| Features | ✓6 features | 4 features |
| States Available | 49 | Not disclosed |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →About ShedRx
Telehealth provider offering compounded GLP-1 medications in injectable, lozenge, and drop formats.
Read our full ShedRx review →Pros & Cons
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
ShedRx
What we like
- Both semaglutide and tirzepatide available
- Compounded GLP-1 access
- Multiple administration formats
Watch-outs
- Limited public information on program details
Our Verdict
ShedRx is our recommended choice here, particularly for mainstream telehealth GLP-1 access. NewSelf is a solid alternative, especially if you want lowest-cost compounded GLP-1 with pharmacy quality transparency — compare the six-dimension breakdown and pricing below to weigh them for your situation.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
Choose ShedRx if…
You want mainstream telehealth GLP-1 access and a starting price around $169/mo.
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DudeMeds
Men seeking no-fee GLP-1 access with oral and injectable options
From $175/mo
Get started →Yucca Health
Mainstream telehealth GLP-1 access
From $146/mo
Get started →TrimRx
Best overall value
From $135/mo
Get started →NewSelf vs ShedRx: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
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