MEDVi vs NewSelf
An in-depth comparison of two leading GLP-1 Providers
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MEDVi
Best for: patients who want the option to switch between compounded and brand-name GLP-1 through one provider
Visit MEDVi →
NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →MEDVi and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $249/mo, and MEDVi is the option we'd start with for most patients. Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
MEDVi
$299 is the locked-in refill price; $179 first-month 'SUMMER Sale' on the main and affiliate-landing funnels; a $149 first-month variant runs on the ?page=multi3 funnel. Affiliate landing (?page=multi) shows $179.
Flat 'Starting at $249' — no intro discount shown.
$99 Membership + Medication Cost — medication cost not published (varies/insurance may reimburse). 'Availability is subject to change.'
$99 Membership + Medication Cost — medication cost not published. COMPOUNDED tirzepatide ($349 in our current entry) is no longer published anywhere on glp1.medvi.org, home.medvi.org, or the intake flow (0 mentions) — treat as discontinued/not published, do not carry the $349 row forward.
NewSelf
All dosages same price
All dosages same price
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What’s included
MEDVi
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Included
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
MEDVi
7.1/10
NewSelf
8.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | MEDVi | NewSelf |
|---|---|---|
| Starting Price | $249/mo | ✓$100/mo |
| Features | ✓7 features | 6 features |
| States Available | 48 | ✓49 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About MEDVi
MEDVi is a telehealth weight-loss platform offering compounded GLP-1 injections and tablets (semaglutide) as well as brand-name Wegovy and Zepbound through licensed US pharmacies. Medical treatment is delivered by OpenLoop Health clinicians and CareGLP Affiliated P.C.s.
Read our full MEDVi review →About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →Pros & Cons
MEDVi
What we like
- Both compounded and brand-name (Wegovy, Zepbound) GLP-1 options in one platform
- Oral tablet and injectable formats
- Named US pharmacy partners (Triad Rx, Precision Medicine, RedRock Pharmacy, Beaker Pharmacy & Compounding)
- Clinical oversight through OpenLoop Health provider network and CareGLP Affiliated P.C.s
- Direct-to-home shipping with 24/7 support
Watch-outs
- Refill price for compounded GLP-1 injection ($299) steps up significantly from $179 first-month offer
- Not available in Mississippi or North Dakota (telehealth regulation constraints)
- Alabama and California patients can only receive injectable formats, not tablets, per state law
- Kansas, Indiana, New Mexico, Oklahoma, and West Virginia require a synchronous provider visit before prescribing
- No LegitScript or PCAB certification disclosed on the site
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Our Verdict
MEDVi is our recommended choice here, particularly for patients who want the option to switch between compounded and brand-name GLP-1 through one provider. NewSelf is a solid alternative, especially if you want lowest-cost compounded GLP-1 with pharmacy quality transparency — compare the six-dimension breakdown and pricing below to weigh them for your situation.
Choose MEDVi if…
You want patients who want the option to switch between compounded and brand-name GLP-1 through one provider and a starting price around $249/mo.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
Ready to start? Vetted GLP-1 providers
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bmiMD
Mainstream telehealth GLP-1 access
From $99/mo
Get started →Synergy Rx
Broadest drug catalog in the Lion MD white-label cluster
From $199/mo
Get started →RxSpan MD
Shoppers wanting physician-led, pharmacy-transparent compounded GLP-1 with brand-name options
From $179/mo
Get started →MEDVi vs NewSelf: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.