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Live Vital vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Live Vital logo

Live Vital

7.7
★★★3.9/5

Best for: shoppers who want low-cost, physician-led compounded GLP-1 with peptide and hormone options

Visit Live Vital
VS
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf

Live Vital and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Live Vital starts lower at $99/mo versus $100/mo, and Live Vital is the option we'd start with for most patients. Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Live Vital

Compounded SemaglutideCompounded
$99/mo
semaglutide

3 month program ($299 total); page live at direct URL but DE-LISTED from the public /treatments catalog, nav, footer, and sitemap

Compounded TirzepatideCompounded
$183/mo
tirzepatide

3 month program ($549 total); page live at direct URL but DE-LISTED from the public /treatments catalog, nav, footer, and sitemap

Retatrutide (triple agonist)Compounded
$299/mo
retatrutide

NEW since our last check; 'Exclusive', prescribed off-label; 'not FDA-approved for weight management and remains in Phase 3 clinical trials'; listed on robots-disallowed /partner-treatments and direct URL only

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

Live Vital

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Live Vital

7.7/10

Overall

NewSelf

8.3/10

Value25%

8.5A
vs
B
9.0

Effectiveness25%

7.5A
vs
B
8.0

User Experience15%

6.5A
vs
B
8.0

Trust & Safety15%

7.3A
vs
B
8.3

Accessibility10%

8.5A
vs
B
8.5

Support10%

8.0A
vs
B
7.9

Features & Coverage

FeatureLive VitalNewSelf
Starting Price$99/mo$100/mo
Features7 features6 features
States Available5049
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About Live Vital

Live Vital is a physician-led telehealth practice founded by Dr. Patrick Taylor, MD, offering compounded GLP-1 weight loss — semaglutide from $99/mo and tirzepatide from $183/mo, billed as 3-month programs — alongside peptide and hormone therapy. Every plan is doctor-prescribed, filled by a licensed US pharmacy, and shipped to your door, with unlimited care-team messaging and no lock-in. Fully telehealth in all 50 states.

Read our full Live Vital review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

Live Vital

What we like

  • Physician-led — founded by Dr. Patrick Taylor, MD; all treatments doctor-prescribed via the clinical team
  • Transparent published pricing: semaglutide from $99/mo, tirzepatide from $183/mo (billed as 3-month programs)
  • Every plan includes doctor prescribing, licensed-pharmacy medication, and direct-to-door shipping
  • Unlimited messaging with the care team; cancel or pause anytime with no lock-in
  • Fully telehealth in all 50 states

Watch-outs

  • Sold as 3-month programs (semaglutide $299 / tirzepatide $549 per quarter); 'starting at' rates can rise with dose
  • Doesn't accept insurance (HSA/FSA funds only)
  • Compounding pharmacy isn't named (only 'a licensed US pharmacy')
  • Also a peptide/longevity practice; those peptides are not FDA-approved (the site discloses this)

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: Live Vital

Live Vital is our recommended choice here, particularly for shoppers who want low-cost, physician-led compounded GLP-1 with peptide and hormone options. NewSelf is a solid alternative, especially if you want lowest-cost compounded GLP-1 with pharmacy quality transparency — compare the six-dimension breakdown and pricing below to weigh them for your situation.

Choose Live Vital if…

You want shoppers who want low-cost, physician-led compounded GLP-1 with peptide and hormone options and a starting price around $99/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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Live Vital vs NewSelf: FAQ

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