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Midi Health vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Midi Health logo

Midi Health

7.0
★★★3.5/5

Best for: menopause-focused care with GLP-1 as a metabolic adjunct

Visit Midi Health
VS
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf

Midi Health and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $164/mo, and Midi Health is the option we'd start with for most patients. Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Midi Health

Self-pay initial visittelehealth visit
$250/mo

Per-visit self-pay fee, NOT a monthly medication price; GLP-1 medication billed separately or through insurance. UPDATED 2026-08-15: the earlier claim that no compounded medication price is published is NO LONGER TRUE — see the ladder rows below, from /glp1-pricing.

Self-pay continued care visittelehealth visit
$150/mo

Per-visit self-pay fee; medication not included. Under insurance you instead pay your standard copay + deductible.

GLP-1 injectable — starting doses (0.1–0.5 mg), 4-week supplyCompounded
$165.9/mo
semaglutide

From /glp1-pricing, headed 'No membership fees. No surprises.' ⚠ EVERY table is labelled '4-week supply', NOT a calendar month, so this is 13 cycles a year and must never be restated as '/mo'. Ladder runs $165.90 (0.1–0.5 mg) to $355.00 (2.5 mg).

Dual-action GLP-1/GIP injectable — starting doses (1.25–2.5 mg), 4-week supplyCompounded
$210/mo
tirzepatide

4-week supply, not a month. Ladder runs $210.00 (1.25–2.5 mg) to $434.00 (13.75–15 mg).

GLP-1 sublingual — starting dose (0.075 mg), 4-week supplyCompounded · oral
$164/mo
semaglutide

4-week supply, not a month. Ladder runs $164.00 (0.075 mg) to $275.00 (0.8 mg).

Dual-action GLP-1/GIP sublingual — starting dose (1 mg), 4-week supplyCompounded · oral
$209/mo
tirzepatide

4-week supply, not a month. Ladder runs $209.00 (1 mg) to $460.00 (7 mg).

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

Midi Health

Inclusions not disclosed.

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Midi Health

7.0/10

Overall

NewSelf

8.3/10

Value25%

7.0A
vs
B
9.0

Effectiveness25%

7.0A
vs
B
8.0

User Experience15%

7.0A
vs
B
8.0

Trust & Safety15%

7.3A
vs
B
8.3

Accessibility10%

6.5A
vs
B
8.5

Support10%

7.0A
vs
B
7.9

Features & Coverage

FeatureMidi HealthNewSelf
Starting Price$164/mo$100/mo
Features5 features6 features
States Available5049
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNone1 warning

About Midi Health

Midi Health is a nationwide 50-state menopause and perimenopause telehealth platform. GLP-1 prescribing is offered as a clinician-discretionary metabolic-health adjunct within the menopause care framework — not as a standalone weight-loss product. Accepts commercial insurance but does NOT accept Medicare, Medicaid, or Medi-Cal.

Read our full Midi Health review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

Midi Health

What we like

  • Available in all 50 states
  • Accepts commercial insurance — a differentiator vs cash-pay-only GLP-1 telehealth
  • Menopause + metabolic-health focus suits women where GLP-1 efficacy and weight regulation overlap most
  • Transparent self-pay visit fees ($250 initial, $150 follow-up); GLP-1 can also be billed through commercial insurance (copay + deductible)

Watch-outs

  • Does not accept Medicare, Medicaid, or Medi-Cal
  • GLP-1 is prescribed at clinician discretion within a menopause plan, not guaranteed at intake
  • Menopause-focused — not the right fit for men or younger women whose main goal is weight loss

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: Midi Health

Midi Health is our recommended choice here, particularly for menopause-focused care with GLP-1 as a metabolic adjunct. NewSelf is a solid alternative, especially if you want lowest-cost compounded GLP-1 with pharmacy quality transparency — compare the six-dimension breakdown and pricing below to weigh them for your situation.

Choose Midi Health if…

You want menopause-focused care with GLP-1 as a metabolic adjunct and a starting price around $164/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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7.1

MEDVi

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7.3

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6.9

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Midi Health vs NewSelf: FAQ

NewSelf is cheaper. Its lowest ongoing monthly cash price is $100/mo, compared with $164/mo for Midi Health. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
For most people we'd start with Midi Health, especially if you want menopause-focused care with GLP-1 as a metabolic adjunct. NewSelf is a strong alternative and may suit you better for lowest-cost compounded GLP-1 with pharmacy quality transparency — weigh the six-dimension breakdown above to decide which fits your priorities.
Midi Health covers more — 50 states versus 49.
Midi Health is an affiliate partner (we may earn a commission on sign-ups through our links); NewSelf is not. Either way, we rank providers editorially with the same scoring framework and disclose every partnership — being a partner does not buy a higher score.
For Semaglutide, NewSelf is cheaper at $100/mo versus $164/mo at Midi Health.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring Midi Health and NewSelf head-to-heads in the same category.

Or see the full category ranking.

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