NewSelf vs Sesame Care
Our featured pick: Sesame Care (affiliate partner). In our scoring, NewSelf scores 8.2 and Sesame Care 8.0 out of 10.
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Key differences
- Price
- NewSelf $100/mo for compounded semaglutide; Sesame Care $349/mo for brand-name Wegovy / Ozempic (different medications, so not compared on price)
- Coverage
- NewSelf 48 states + PR (Sesame Care doesn't publish a state list)
- Included
- NewSelf: medication, clinician visits, shipping; Sesame Care: not stated
- Safety
- FDA warning letters on record: NewSelf 1, Sesame Care none
NewSelf
Best for lowest-cost compounded GLP-1 at one price for every dose, if a 3-month commitment works for you
semaglutide
$100
on a 3-month prepaid plan
Our score 8.2/10
Sesame Care
Affiliate partnerBest for Brand-name GLP-1s at cash prices, no compounding
Brand-name Wegovy / Ozempic
$349
$199 first month
Our score 8.0/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
NewSelf
Sesame Care
Price
Semaglutide / month
$100/mo
on a 3-month prepaid plan
Not listed
Tirzepatide / month
$144/mo
on a 3-month prepaid plan
Not listed
Brand Wegovy / Ozempic / month
Not listed
$349/mo
$199 first month
Brand Zepbound / Mounjaro / month
Not listed
$299/mo
Brand Wegovy pill / Rybelsus / month
Not listed
$149/mo
Brand Foundayo / month
Not listed
$149/mo
Coverage
State availability
48 states + PR
List not published
Oral option listed
Not listed
Yes
Brand-name access listed
Not listed
Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo
Included in the price
Medication, clinician visits, shipping
Not disclosed
Terms & safety
Price shown
Before intake
Before intake
Video visit
Not disclosed
Required
Cancel anytime
No
Better on this row: Yes
Minimum commitment
3-month plan for the listed price
None
Refunds
No refunds after the doctor visit; full refund if the doctor declines; $99 fee if you cancel before the visit
Not disclosed
Early-cancellation fee
Yes
Better on this row: None
FDA warning letters
1 warning letter
Better on this row: None on record
Provider facts checked
October 2026
August 2026
Every dose and plan: NewSelf · Sesame Care
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose NewSelf if…
- Lists compounded semaglutide and compounded tirzepatide, which Sesame Care doesn't price
- Publishes its full state list (48 states + PR)
- Same price at every dose, so your bill doesn't rise as you titrate up
What to weigh up
- 1 FDA warning letter on record
- Its $100/mo compounded semaglutide price needs a 3-month prepaid plan
Choose Sesame Care if…
- Lists brand-name Wegovy / Ozempic, brand-name Zepbound / Mounjaro and brand-name Wegovy pill / Rybelsus, which NewSelf doesn't price
- Cancel anytime; No early-cancellation fee
- No FDA warning letters on record (NewSelf has 1)
What to weigh up
- No published state list; confirm yours at signup
- Marketplace model means clinician credentials and quality vary provider to provider
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
NewSelf
8.2/10
Sesame Care
8.0/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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From $299/mo
Get started →SkinnyRx
Compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price
Read full review →From $149.25/mo
Get started →Collective
The lowest flat medication price if you can absorb an annual membership fee
Read full review →From $59/mo + membership
Get started →NewSelf vs Sesame Care: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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- Sesame Care vs Amazon One Medical
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.