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altRX vs Amazon One Medical

Our featured pick: altRX (affiliate partner). In our scoring, altRX scores 7.4 and Amazon One Medical 8.5 out of 10, and Amazon One Medical costs less for brand-name Wegovy / Ozempic (about $11,201 a year less; one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost).

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed

Key differences

Price
Amazon One Medical $199/mo vs altRX $1,149/mo for brand-name Wegovy / Ozempic (standing prices, no prepay or separate membership listed · about $11,201 a year less with Amazon One Medical · one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
Coverage
Amazon One Medical 50 states (altRX doesn't publish a state list)
Included
altRX: medication, clinician visits, shipping; Amazon One Medical: clinician visits, shipping (not included: medication, labs)
Safety
FDA warning letters on record: altRX 1, Amazon One Medical none

How we compare providers

altRX logo

altRX

Affiliate partner

Also prices compounded semaglutide and tirzepatide

semaglutide

$89/mo

Our score 7.4/10

Amazon One Medical logo

Amazon One Medical

Best for brand-name GLP-1s with published per-dose cash prices and Amazon Pharmacy delivery

Brand-name Wegovy / Ozempic

$199/mo

billed every 4 weeks

Our score 8.5/10

We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.

Costs & coverage

Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.

altRX

Amazon One Medical

Price

Brand Wegovy / Ozempic / month

$1,149/mo

Better on this row: $199/mo

billed every 4 weeks

Brand Wegovy / Ozempic / year (modeled)

$13,788

Better on this row: $2,587

13 charges

Brand Zepbound / Mounjaro / month

$1,249/mo

Better on this row: $299/mo

billed every 4 weeks

Brand Zepbound / Mounjaro / year (modeled)

$14,988

Better on this row: $3,887

13 charges

Semaglutide / month

$89/mo

Not listed

Tirzepatide / month

$149/mo

Not listed

Brand Wegovy pill / Rybelsus / month

Not listed

$149/mo

Brand Foundayo / month

Not listed

$149/mo

Coverage

State availability

List not published

50 states

Oral option listed

Not listed

Yes

Brand-name access listed

Wegovy / Ozempic, Zepbound / Mounjaro

Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo

Included in the price

Medication, clinician visits, shipping

Clinician visits, shipping

Not included: medication, labs

Terms & safety

Price shown

Before intake

Before intake

Lab work

Not disclosed

Required

Cancel anytime

Yes

Not disclosed

Minimum commitment

Single-month and multi-month plans; multi-month plans are a single, non-refundable purchase for the full term

Not disclosed

Refunds

Refund policy (Aug 25, 2026): 'ALL PAYMENTS FOR THE SUBSCRIPTION SERVICES ARE FINAL AND NON-REFUNDABLE AT THE TIME OF PURCHASE.' A medical disqualification refunds the unused portion minus consultations, provider review and other services already rendered.

Not disclosed

FDA warning letters

1 warning letter

Better on this row: None on record

Provider facts checked

October 2026

October 2026

Every dose and plan: altRX · Amazon One Medical

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Which fits your priorities?

Only the points where these two differ, from the table above and each provider’s record.

altRX logo

Choose altRX if…

  • Lists compounded semaglutide and compounded tirzepatide, which Amazon One Medical doesn't price
  • Price includes medication; Amazon One Medical's doesn't
  • Brand-name Zepbound, Wegovy and Ozempic available alongside compounded options

What to weigh up

  • 1 FDA warning letter on record
  • About $11,201 a year more than Amazon One Medical for brand-name Wegovy / Ozempic (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
Amazon One Medical logo

Choose Amazon One Medical if…

  • About $11,201 a year less than altRX for brand-name Wegovy / Ozempic at standing prices (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
  • Lists brand-name Wegovy pill / Rybelsus and brand-name Foundayo, which altRX doesn't price
  • Publishes its full state list (50 states)

What to weigh up

  • Price doesn't include medication
  • Online On-Demand Care is cash-only for medication; insurance needs scheduled visits near a One Medical office

Explore the scoring factors

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

altRX

7.4/10

Overall

Amazon One Medical

8.5/10

Value25%

7.5A
vs
B
8.5

Effectiveness25%

8.0A
vs
B
8.5

User Experience15%

7.0A
vs
B
8.0

Trust & Safety15%

6.8A
vs
B
8.8

Accessibility10%

7.0A
vs
B
9.5

Support10%

7.4A
vs
B
8.0

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7.6

SkinnyRx

Compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price

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From $149.25/mo

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8.3

Collective

The lowest flat medication price if you can absorb an annual membership fee

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From $59/mo + membership

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7.4

MadeMed

Compounded GLP-1 in both injection and oral forms

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From $219/mo

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altRX vs Amazon One Medical: FAQ

For brand-name Wegovy / Ozempic, Amazon One Medical costs less: about $11,201 less a year at the standing price, with no prepay or separate membership listed (not a first-month promo); one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost. See Costs & coverage above for each medication side by side.
Our featured pick is altRX, our affiliate partner. Partner status affects which provider we feature, never the scores: on our six-dimension score, altRX is 7.4/10 and Amazon One Medical 8.5/10, so check the key differences and the breakdown above before you choose.
altRX is an affiliate partner (we may earn a commission on sign-ups through our links); Amazon One Medical is not. Either way, we rank providers editorially with the same scoring framework and disclose every partnership — being a partner does not buy a higher score.
altRX: $1,149, about $13,788 a year. Amazon One Medical: $199 (billed every 4 weeks, 13 charges a year), about $2,587 a year. Amazon One Medical costs about $11,201 less a year at these prices.
altRX doesn't publish a state list. Amazon One Medical publishes 50 states. Where a list isn't published, confirm your state during sign-up before paying.
altRX: cancel anytime — yes; minimum commitment — Single-month and multi-month plans; multi-month plans are a single, non-refundable purchase for the full term; early-cancellation fee — not disclosed. Amazon One Medical doesn't state its cancellation terms. Check the provider's own terms before you buy.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring altRX and Amazon One Medical head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.