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altRX vs Amazon One Medical

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
altRX logo

altRX

7.3
★★★3.7/5

Best for: the only platform offering all four brand-name GLP-1s plus compounded

Visit altRX
VS
Amazon One Medical logo

Amazon One Medical

8.5
★★★★4.3/5

Best for: the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings

Visit Amazon One Medical

altRX and Amazon One Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, both start around $149/mo, and Amazon One Medical edges ahead overall (8.5 vs 7.3 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

altRX

Compounded GLP-1 (semaglutide) starting tierCompounded
$149/mo
semaglutide
Compounded GLP-1/GIP (tirzepatide) starting tierCompounded
$249/mo
tirzepatide
Brand-name Ozempic®Brand-name
$1149/mo
semaglutide
Brand-name Mounjaro®Brand-name
$1249/mo
tirzepatide
Brand-name Zepbound®Brand-name
$1249/mo
tirzepatide
Brand-name Wegovy®Brand-name
$1579/mo
semaglutide

Amazon One Medical

Foundayo (with insurance + Lilly Savings Card)Brand-name
$25/mo
orforglipron
Foundayo (cash pay)Brand-name
$149/mo
orforglipron

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What’s included

altRX

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Amazon One Medical

What the monthly price covers

Medication

Billed separately

Provider visits

Included

Shipping

Included

Lab work

Billed separately

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

altRX

7.3/10

Overall

Amazon One Medical

8.5/10

Value25%

7.0A
vs
B
8.5

Effectiveness25%

8.0A
vs
B
8.5

User Experience15%

7.0A
vs
B
8.0

Trust & Safety15%

7.3A
vs
B
8.8

Accessibility10%

7.0A
vs
B
9.5

Support10%

7.4A
vs
B
8.0

Features & Coverage

FeaturealtRXAmazon One Medical
Starting Price$149/mo$149/mo
Features8 features6 features
States AvailableNot disclosed50
Compounded✓ Yes
Brand Name✓ Yes✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About altRX

altRX is a dual-modality telehealth platform offering compounded GLP-1s plus all four brand-name FDA-approved options — Mounjaro, Ozempic, Wegovy, and Zepbound — the most comprehensive brand-name lineup in our directory. It's LegitScript-certified and publishes the FDA compounded-medication disclaimer. Compounded plans start at $149 (semaglutide) and $249 (tirzepatide); brand-name pricing runs $1,149–$1,579, all-inclusive of consult and shipping.

Read our full altRX review →

About Amazon One Medical

Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.

Read our full Amazon One Medical review →

Pros & Cons

altRX

What we like

  • Offers all four brand-name FDA-approved GLP-1s (Mounjaro, Ozempic, Wegovy, Zepbound) — the most comprehensive brand-name access we've reviewed
  • LegitScript Certified with a publicly verifiable seal
  • Publishes the FDA compounded-medication disclaimer
  • Transparent pricing across all six product tiers (compounded plus four brand-name)
  • All-inclusive pricing — consult, prescription, and shipping with no hidden fees
  • Corporate structure disclosed (CareGLP affiliated P.C.s plus CareValidate Health)
  • 1-day approval — faster than typical 24–72 hour competitors
  • Brand-name pricing competitive vs retail cash-pay

Watch-outs

  • States-served list not disclosed
  • 503A/503B pharmacy partner not named (only 'multiple USA-certified pharmacies')
  • 503A vs 503B designation not specified
  • No named medical director
  • Corporate physical address not disclosed
  • Governing law / arbitration venue not disclosed
  • Brand-name pricing is cash-pay only — patients with commercial coverage should price-check first
  • Affiliated-P.C. structure is unusual and may mean a state-by-state setup rather than one national entity

Amazon One Medical

What we like

  • As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
  • Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
  • In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
  • Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
  • Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
  • Delivering GLP-1 medications since 2021 — track record on cold-chain logistics

Watch-outs

  • Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
  • Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
  • Pricing is set by manufacturer savings programs and can change at any time
  • No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
  • Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
  • Copays and deductibles still apply to the clinical visit

Our Verdict

Winner: Amazon One Medical

Amazon One Medical edges out altRX with a higher overall score of 8.5/10 and is particularly strong for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings. altRX remains a solid alternative, especially if you're looking for the only platform offering all four brand-name GLP-1s plus compounded.

Choose altRX if…

You want the only platform offering all four brand-name GLP-1s plus compounded and a starting price around $149/mo.

Choose Amazon One Medical if…

You want the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings and a starting price around $149/mo.

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altRX vs Amazon One Medical: FAQ

Key terms, explained

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.