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AgelessRx vs Amazon One Medical

Our featured pick: AgelessRx (affiliate partner). In our scoring, AgelessRx scores 7.1 and Amazon One Medical 8.5 out of 10, and Amazon One Medical costs less for brand-name Wegovy / Ozempic (about $2,381 a year less; one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost).

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed

Key differences

Price
Amazon One Medical $199/mo vs AgelessRx $414/mo for brand-name Wegovy / Ozempic (standing prices, no prepay or separate membership listed · about $2,381 a year less with Amazon One Medical · one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
Coverage
Amazon One Medical 50 states (AgelessRx doesn't publish a state list)
Included
AgelessRx: medication, clinician visits, shipping; Amazon One Medical: clinician visits, shipping (not included: medication, labs)

How we compare providers

AgelessRx logo

AgelessRx

Affiliate partner

Best for longevity-focused GLP-1 care with microdosing and brand-name options

semaglutide

$159/mo

Our score 7.1/10

Amazon One Medical logo

Amazon One Medical

Best for brand-name GLP-1s with published per-dose cash prices and Amazon Pharmacy delivery

Brand-name Wegovy / Ozempic

$199/mo

billed every 4 weeks

Our score 8.5/10

We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.

Costs & coverage

Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.

AgelessRx

Amazon One Medical

Price

Brand Wegovy / Ozempic / month

$414/mo

$264 first month

Better on this row: $199/mo

billed every 4 weeks

Brand Wegovy / Ozempic / year (modeled)

$4,968

Better on this row: $2,587

13 charges

Brand Zepbound / Mounjaro / month

$514/mo

$364 first month

Better on this row: $299/mo

billed every 4 weeks

Brand Zepbound / Mounjaro / year (modeled)

$6,168

Better on this row: $3,887

13 charges

Brand Wegovy pill / Rybelsus / month

$349/mo

$199 first month

Better on this row: $149/mo

Brand Wegovy pill / Rybelsus / year (modeled)

$4,188

Better on this row: $1,788

Semaglutide / month

$159/mo

Not listed

Tirzepatide / month

$209/mo

$109 first month

Not listed

Brand Foundayo / month

Not listed

$149/mo

Coverage

State availability

List not published

50 states

Oral option listed

Yes

Yes

Brand-name access listed

Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus

Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo

Included in the price

Medication, clinician visits, shipping

Clinician visits, shipping

Not included: medication, labs

Terms & safety

Price shown

Before intake

Before intake

Lab work

Not disclosed

Required

Cancel anytime

Yes

Not disclosed

Minimum commitment

Monthly, 2-month and 4-month plans; the lowest advertised compounded prices require the 4-month plan billed in full

Not disclosed

Refunds

FAQ: 'AgelessRx cannot guarantee refunds for any cancellation requests received after our pharmacy partner has received your order... does not accept returns nor can we offer any refunds for any prescription product once it has left our pharmacy partner.'

Not disclosed

FDA warning letters

None on record

None on record

Provider facts checked

October 2026

October 2026

Every dose and plan: AgelessRx · Amazon One Medical

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Which fits your priorities?

Only the points where these two differ, from the table above and each provider’s record.

AgelessRx logo

Choose AgelessRx if…

  • Lists compounded semaglutide and compounded tirzepatide, which Amazon One Medical doesn't price
  • Price includes medication; Amazon One Medical's doesn't
  • Named, in-house medical team led by a medical director, with care based in Ann Arbor, MI

What to weigh up

  • About $2,381 a year more than Amazon One Medical for brand-name Wegovy / Ozempic (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
  • No published state list; confirm yours at signup
Amazon One Medical logo

Choose Amazon One Medical if…

  • About $2,381 a year less than AgelessRx for brand-name Wegovy / Ozempic at standing prices (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
  • Lists brand-name Foundayo, which AgelessRx doesn't price
  • Publishes its full state list (50 states)

What to weigh up

  • Price doesn't include medication
  • Online On-Demand Care is cash-only for medication; insurance needs scheduled visits near a One Medical office

Explore the scoring factors

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

AgelessRx

7.1/10

Overall

Amazon One Medical

8.5/10

Value25%

7.0A
vs
B
8.5

Effectiveness25%

7.0A
vs
B
8.5

User Experience15%

7.0A
vs
B
8.0

Trust & Safety15%

7.3A
vs
B
8.8

Accessibility10%

7.5A
vs
B
9.5

Support10%

7.4A
vs
B
8.0

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AgelessRx vs Amazon One Medical: FAQ

For brand-name Wegovy / Ozempic, Amazon One Medical costs less: about $2,381 less a year at the standing price, with no prepay or separate membership listed (not a first-month promo); one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost. See Costs & coverage above for each medication side by side.
Our featured pick is AgelessRx, our affiliate partner. Partner status affects which provider we feature, never the scores: on our six-dimension score, AgelessRx is 7.1/10 and Amazon One Medical 8.5/10, so check the key differences and the breakdown above before you choose.
AgelessRx is an affiliate partner (we may earn a commission on sign-ups through our links); Amazon One Medical is not. Either way, we rank providers editorially with the same scoring framework and disclose every partnership — being a partner does not buy a higher score.
AgelessRx: $414, about $4,968 a year; first month $264. Amazon One Medical: $199 (billed every 4 weeks, 13 charges a year), about $2,587 a year. Amazon One Medical costs about $2,381 less a year at these prices.
AgelessRx doesn't publish a state list. Amazon One Medical publishes 50 states. Where a list isn't published, confirm your state during sign-up before paying.
AgelessRx: cancel anytime — yes; minimum commitment — Monthly, 2-month and 4-month plans; the lowest advertised compounded prices require the 4-month plan billed in full; early-cancellation fee — not disclosed. Amazon One Medical doesn't state its cancellation terms. Check the provider's own terms before you buy.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring AgelessRx and Amazon One Medical head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.