TMates vs TrimRx
In our scoring, TrimRx edges ahead overall (7.7 vs 6.9 out of 10), and TrimRx costs less for compounded semaglutide (about $840 a year less).
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Key differences
- Price
- TrimRx $179/mo vs TMates $249/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $840 a year less with TrimRx)
- Coverage
- TMates 50 states (TrimRx doesn't publish a state list)
- Included
- TMates: medication, clinician visits, shipping, coaching; TrimRx: medication, clinician visits, shipping
TMates
Affiliate partnerBest for nationwide compounded GLP-1 availability including Puerto Rico
semaglutide
$249
Our score 6.9/10
TrimRx
Affiliate partnerBest for best overall value
semaglutide
$179
$149 first month
Our score 7.7/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
TMates
TrimRx
Price
Semaglutide / month
$249/mo
Better on this row: $179/mo
$149 first month
Semaglutide / year (modeled)
$2,988
Better on this row: $2,148
Tirzepatide / month
$297/mo
Better on this row: $259/mo
Tirzepatide / year (modeled)
$3,564
Better on this row: $3,108
Brand Wegovy / Ozempic / month
Not listed
$1,579/mo
Brand Zepbound / Mounjaro / month
Not listed
$1,249/mo
Coverage
State availability
50 states
List not published
Brand-name access listed
Not listed
Wegovy / Ozempic, Zepbound / Mounjaro
Included in the price
Medication, clinician visits, shipping, coaching
Medication, clinician visits, shipping
Terms & safety
Price shown
Before intake
Before intake
Cancel anytime
Yes
Not disclosed
Minimum commitment
None
Not disclosed
FDA warning letters
None on record
None on record
Provider facts checked
August 2026
August 2026
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose TMates if…
- Publishes its full state list (50 states)
- All-inclusive monthly price covers medication, consults, nutrition coaching, and 24/7 support — no separate membership fee
- Fast stated turnaround — 2–3 days from intake to delivery
What to weigh up
- About $840 a year more than TrimRx for compounded semaglutide
- No third-party pharmacy accreditation (no LegitScript, PCAB, ACHC, or NABP)
Choose TrimRx if…
- About $840 a year less than TMates for compounded semaglutide at standing prices
- Lists brand-name Wegovy / Ozempic and brand-name Zepbound / Mounjaro, which TMates doesn't price
- Free shipping with medication delivered to your door monthly — can start as soon as the next day
What to weigh up
- No published state list; confirm yours at signup
- Async, questionnaire-based intake — no mandatory video visit with a clinician before prescribing
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
TMates
6.9/10
TrimRx
7.7/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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TMates vs TrimRx: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.