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TrimRx vs ShedRx

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
TrimRx logo

TrimRx

7.7
★★★3.9/5

Best for: best overall value

Visit TrimRx
VS
ShedRx logo

ShedRx

8.0
★★★★4/5

Best for: mainstream telehealth GLP-1 access

Visit ShedRx

TrimRx and ShedRx are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, ShedRx starts lower at $169/mo versus $179/mo, and ShedRx edges ahead overall (8.0 vs 7.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

TrimRx

Starting (flat across doses)Compounded
$179$135/mo
Save 25% right now
semaglutide

Homepage tier 'GLP-1 Starting at $179'; hero checkout mockup shows $299.00 list struck to $179.00/1st mo; email-capture popup offers '$120 OFF for your first order — GET YOUR FIRST MONTH AS LOW AS $135'. Multi-month bundle prices ($209/$191/$174 recorded 2026-07-10) are NO LONGER published — old public checkout 404s, plans now quiz-gated.

Starting (flat across doses)Compounded
$259/mo
tirzepatide

Homepage tier 'GLP-1 + GIP Starting at $259' (hero mockup: 'GLP-1 + GIP Medication Contains Tirzepatide') — DOWN from the $279 checkout limited offer we recorded 2026-07-10; bundle prices ($316/$299/$283) no longer published (quiz-gated).

StartingBrand-name
$1249/mo
tirzepatide (mounjaro)

'Mounjaro® Starting at $1249' homepage tile; same branded-fulfillment caveat.

StartingBrand-name
$1249/mo
tirzepatide (zepbound)

'Zepbound® Starting at $1249' homepage tile; same branded-fulfillment caveat.

StartingBrand-name
$1579/mo
semaglutide (wegovy)

'Wegovy® Starting at $1579' homepage tile; same branded-fulfillment caveat.

ShedRx

InjectableCompounded
$199$159/mo
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semaglutide

$199 1-month / $179 6-month / $159 12-month plan; promo_price = 12-month commitment rate, not a temporary promo

DropsCompounded
$229/mo
semaglutide

Starting at $229/month; 'Medication and supplies included | Member support | Free shipping' (up from $199 in our record)

LozengesCompounded
$199/mo
semaglutide

Starting at $199/month, month-to-month; free shipping stated (replaces our obsolete 'Oral $349' row)

InjectableCompounded
$299$239/mo
Save 20% right now
tirzepatide

$299 1-month / $269 6-month / $239 12-month plan; promo_price = 12-month commitment rate

Daily pillCompounded · oral
$149/mo
orforglipron

NEW product. $149/mo medication (cash pay, paid to dispensing pharmacy) + $125/mo Shed membership and provider fee

Pen weekly / pill dailyCompounded
$149/mo
semaglutide

Page shows BOTH: FAQ 'starts at $149 (pill) and $199 (pen)... new patients using cash pay' + '$99 Shed membership', while hero states '$349-499 for the medication' + '$125/month Shed Membership'. Medication purchased directly via NovoCare; membership fee inconsistency ($99 vs $125) on same page

VialCompounded
$349/mo
tirzepatide

FAQ: 'starts at $349 per month for new patients using cash pay' + $99 membership per FAQ ($125/mo per hero); medication purchased directly via LillyDirect

DailyCompounded · oral
$169/mo
metformin + naltrexone + topiramate

Starting at $169/month; 'Includes 2 Health Coaching sessions per month'

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What’s included

TrimRx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

ShedRx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Not disclosed

Lab work

Not disclosed

Coaching

Included

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

TrimRx

7.7/10

Overall

ShedRx

8.0/10

Value25%

8.0A
vs
B
7.5

Effectiveness25%

8.5A
vs
B
9.0

User Experience15%

7.5A
vs
B
8.0

Trust & Safety15%

6.8A
vs
B
7.3

Accessibility10%

7.0A
vs
B
7.5

Support10%

7.5A
vs
B
8.0

Features & Coverage

FeatureTrimRxShedRx
Starting Price$179/mo$169/mo
Features8 features4 features
States AvailableNot disclosedNot disclosed
Compounded✓ Yes✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About TrimRx

TrimRx is a telehealth weight-loss program offering compounded semaglutide and tirzepatide prescribed by licensed US medical providers after an online medical-history review, with medication shipped monthly and free shipping. It leans on price stability and dose continuity — "switch and keep your current dose, no price hikes" — and needs no insurance (cash-pay, tiered monthly pricing plus multi-month bundles). Compounded GLP-1s are not FDA-approved. The compounding pharmacy and state list are not published, specifics are gated behind the intake quiz, and no LegitScript certification is shown.

Read our full TrimRx review →

About ShedRx

Telehealth provider offering compounded GLP-1 medications in injectable, lozenge, and drop formats.

Read our full ShedRx review →

Pros & Cons

TrimRx

What we like

  • Compounded semaglutide and tirzepatide, both prescribed by licensed US medical providers after an online medical-history review
  • Free shipping with medication delivered to your door monthly — can start as soon as the next day
  • Price-stability positioning: "switch and keep your current dose," with no advertised mid-program price hikes
  • Tiered monthly pricing from ~$179/mo plus discounted multi-month bundles; no insurance required (cash-pay)
  • 24/7 patient portal for support; publishes HIPAA, privacy, SMS, and terms policies

Watch-outs

  • Async, questionnaire-based intake — no mandatory video visit with a clinician before prescribing
  • Compounded semaglutide is not FDA-approved (the site discloses this) — it is not brand Wegovy or Ozempic
  • Injectable-only — compounded semaglutide and tirzepatide are advertised, no oral form; program specifics are gated behind the intake quiz
  • Compounding pharmacy partner is not named, and the state-availability list is not published
  • Pricing tiers and program details are gated behind the intake quiz; no LegitScript certification displayed

ShedRx

What we like

  • Both semaglutide and tirzepatide available
  • Compounded GLP-1 access
  • Multiple administration formats

Watch-outs

  • Limited public information on program details

Our Verdict

Winner: ShedRx

ShedRx edges out TrimRx with a higher overall score of 8.0/10 and is particularly strong for mainstream telehealth GLP-1 access. TrimRx remains a solid alternative, especially if you're looking for best overall value.

Choose TrimRx if…

You want best overall value and a starting price around $179/mo.

Choose ShedRx if…

You want mainstream telehealth GLP-1 access and a starting price around $169/mo.

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8.0

ShedRx

Mainstream telehealth GLP-1 access

8.1

bmiMD

Mainstream telehealth GLP-1 access

7.6

RNK Health

Compounded GLP-1 alongside NAD+, peptide and longevity add-ons

TrimRx vs ShedRx: FAQ

Key terms, explained

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Continue exploring TrimRx and ShedRx head-to-heads in the same category.

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.